Magnesium-copper coating for bone implant and preparation method thereof

Abstract

In order to solve the osseointegration and infection problems of implant materials, the invention provides a magnesium-copper coating for bone implantation and a preparation method thereof. Chemical vapor deposition technology and vapor plating technology are employed to prepare a metal magnesium-copper coating on titanium and titanium alloy, cobalt based alloy, stainless steel, polymer material or reticulated vitreous carbon, the thickness of the coating is 0.1-200 micrometers, and the mass ratio of copper element in the coating is greater than 0% and smaller than or equal to 10%. The coating and the method provided by the invention can solve the problems of bone compatibility and infection in existing implant materials, and a permanent implant material prepared by the method is suitable for the mechanical property requirements of various implantation positions, has excellent biocompatibility, and also has sterilization function.

Description

technical field

[0001] The invention belongs to the field of medical materials, in particular to dental implants, joint replacements and filling materials for human tissue defects and the field of implant material antibacterial technology; specifically, the magnesium-copper coating material on the surface of implants and its preparation method . Background technique

[0002] Implants such as artificial joints only have a lifespan of 10-15 years due to adverse cell reactions caused by implant loosening and abrasion, which cannot meet the long-term use requirements. Meanwhile, infection remains one of the disastrous postoperative complications of orthopedic implants. Metallic foreign bodies implanted in the body are risk factors for such infections, and a series of in vivo reactions, including the weakening of macrophage function and the passivation of the local immune system, create favorable conditions for the proliferation of pathogens. In addition, the proteins adsorbed ...

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