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Chinese herbal medicine compound preparation for treating primary osteoporosis and preparation method thereof

A technology for osteoporosis and compound preparations, which is used in pharmaceutical formulations, medical preparations containing active ingredients, bone diseases, etc., and can solve the problems of patients with mildew and deterioration and inconvenience.

Inactive Publication Date: 2017-09-22
LONGHUA HOSPITAL SHANGHAI UNIV OF TRADITIONAL CHINESE MEDICINE
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

The representative prescription of "seeking yang in yin" is Yougui Pill, which has a large number of clinical reports. The treatment of osteoporosis with Yougui Pill has achieved good curative effect, but there are still the following deficiencies in medical practice: the curative effect needs to be consolidated, To reduce recurrence as much as possible, Chinese medicine decoction needs to be decocted temporarily before taking it, and it is prone to mildew and deterioration after long-term storage, which will cause inconvenience to patients, etc.

Method used

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  • Chinese herbal medicine compound preparation for treating primary osteoporosis and preparation method thereof
  • Chinese herbal medicine compound preparation for treating primary osteoporosis and preparation method thereof
  • Chinese herbal medicine compound preparation for treating primary osteoporosis and preparation method thereof

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0047] The proportion of raw materials by weight: Epimedium 30g, Rhizoma Drynariae 30g, Ligustrum lucidum 30g, Achyranthes Bidentata 30g, and Lihuo 25g.

Embodiment 2

[0049] The proportion of raw materials by weight: Epimedium 25g, Rhizoma Drynariae 25g, Ligustrum lucidum 25g, Achyranthes bidentata 25g, and Alcohol 20g.

Embodiment 3

[0051] The proportion of raw materials in parts by weight: Epimedium 20g, Rhizoma Drynariae 20g, Ligustrum lucidum 20g, Achyranthes Bidentata 20g, and Alone 15g.

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Abstract

The invention discloses a Chinese herbal medicine compound preparation for treating primary osteoporosis. The preparation is prepared from a kidney tonifying Chinese herbal medicine and medical adjuvant. The kidney tonifying Chinese herbal medicine is prepared from, by weight, 30-9 parts of Herba epimedii, 30-9 parts of Rhizoma Drynariae, 30-9 parts of glossy privet fruit, 30-9 parts of Achyranthes bidentata and 25-6 parts of Angelica pubescens. According to the preparation, the treating rule of kidney warming and reinforcing is followed. Animal experiments show that high-level bone resorption and bone formation caused by ovariectomization can be reduced, so that a balanced state that bone formation is higher than bone resorption is recovered, and the bone mass is increased; osteocalcin secretion is promoted, and the osteogenic differentiation capacity is improved. By means of the preparation, symptoms of primary osteoporosis can be relieved, recurrence is reduced, and the therapeutic effect is consolidated; the problems of temporary decoction before taking Chinese herbal decoction, molding and deterioration due to placement for a long time and inconvenience brought to a patient can be avoided.

Description

Technical field [0001] The invention relates to a traditional Chinese medicine compound preparation for treating primary osteoporosis. In addition, the invention also relates to a preparation method of the Chinese medicine compound preparation. Background technique [0002] Osteoporosis is the most common metabolic bone disease in humans. The clinical manifestations are bone pain, low back pain, hunchback, and increased bone fragility, which can cause fractures under slight external force. Approximately 200 million people worldwide suffer from osteoporosis. Approximately 75 million people are affected in the United States, Europe, and Japan, including one-third of postmenopausal women. [0003] my country has entered an aging society. By 2015, the total number of elderly people will reach 221 million, accounting for 16% of the total population. The incidence of primary osteoporosis is also increasing (53.8% for women aged 60-64, 70% for 65-69 years old), and the incidence of acc...

Claims

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Application Information

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IPC IPC(8): A61K36/638A61P19/10
CPCA61K36/126A61K36/21A61K36/232A61K36/296A61K36/638A61K2236/331A61K2236/39A61K2236/53A61K2300/00
Inventor 王拥军唐德志张宁舒冰李晨光赵永见笪巍伟李强王强赵东峰王晶刘书芬杨铸卞琴杨锋施杞
Owner LONGHUA HOSPITAL SHANGHAI UNIV OF TRADITIONAL CHINESE MEDICINE
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