A kind of traditional Chinese medicine composition and its preparation, preparation method and application

A composition and technology of traditional Chinese medicine, applied in the field of preparation of traditional Chinese medicine composition and its preparation for the treatment of hyperuricemia, can solve the problems of low solubility, high price, limited effect, etc., to reduce the concentration of uric acid, ensure curative effect, auricle The effect of swelling suppression

Active Publication Date: 2021-12-07
SHANGHAI UNIV OF T C M
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

However, when the reabsorption process of uric acid is inhibited, a large amount of uric acid will enter the kidney, and weakly acidic uric acid will have lower solubility in urine with a lower pH, and it is easier to precipitate crystals in the kidney, causing kidney damage
Uracase representative drug is expensive and limited

Method used

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  • A kind of traditional Chinese medicine composition and its preparation, preparation method and application
  • A kind of traditional Chinese medicine composition and its preparation, preparation method and application
  • A kind of traditional Chinese medicine composition and its preparation, preparation method and application

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0031] Weigh the following raw materials by weight: 15 g of Coix root, 10 g of fenugreek, 5 g of Wang Bu Liuxing, 6 g of Wei Lingxian, and 5 g of loofah. After weighing the raw materials, add water, soak, and extract with water for 3 times, 1 hour each time, combine the decoctions, filter, and concentrate the filtrate under reduced pressure to an extract with a density of 1.10-1.15 (60°C), and dry under reduced pressure. Pulverize, sieve, add appropriate amount of dextrin, use ethanol solution as wetting agent, make soft material, granulate, dry, and granulate.

Embodiment 2

[0033] Weigh the following raw materials by weight: 20 g of coix root, 12 g of powdered coix seed, 6 g of Wang Bu Liuxing, 9 g of Wei Lingxian, and 9 g of loofah. After weighing the raw materials, add water, soak, and extract with water for 3 times, 1 hour each time, combine the decoctions, filter, and concentrate the filtrate under reduced pressure to an extract with a density of 1.10-1.15 (60°C), and dry under reduced pressure. Pulverize, sieve, add appropriate amount of dextrin, use ethanol solution as wetting agent, make soft material, granulate, dry, and granulate.

Embodiment 3

[0035] Weigh the following raw materials by weight: 30 g of coix root, 15 g of powdered birch, 10 g of Wang Bu Liuxing, 10 g of Wei Lingxian, and 12 g of loofah. After weighing the raw materials, add water, soak, and extract with water for 3 times, 1 hour each time, combine the decoctions, filter, and concentrate the filtrate under reduced pressure to an extract with a density of 1.10-1.15 (60°C), and dry under reduced pressure. Pulverize, sieve, add appropriate amount of dextrin, use ethanol solution as wetting agent, make soft material, granulate, dry, and granulate.

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Abstract

The invention relates to the field of traditional Chinese medicines, in particular to a traditional Chinese medicine composition for treating hyperuricemia, which consists of 15-30g coix root, 10-15g fennel, 5-10g wangbuliixing, 6-10g clematis, and loofah 5‑12g made. The invention also provides a traditional Chinese medicine compound preparation for treating hyperuricemia, its preparation method and application. The traditional Chinese medicine composition and its preparation of the present invention treat hyperuricemia by reducing uric acid, and treat a series of diseases caused by high uric acid, such as gouty arthritis, uric acid nephropathy and the like.

Description

technical field [0001] The invention belongs to the technical field of traditional Chinese medicine, and in particular relates to a traditional Chinese medicine composition for treating hyperuricemia and its preparation, preparation method and application. Background technique [0002] Hyperuricemia (HUA) refers to the state of adult plasma uric acid concentration ≥ 7 mg / dL (male) or 5.6 mg / dL (female), mainly due to the disorder of purine metabolism in the human body that leads to excessive production of uric acid and / or Metabolic diseases caused by decreased uric acid excretion. [0003] Gout is an inflammatory reaction caused by the precipitation of monosodium urate crystals in the joint cavity, cartilage and kidney, etc. It is directly related to hyperuricemia caused by disturbance of purine metabolism and / or reduced excretion of uric acid. High uric acid levels act on vascular tissue, pancreatic islets and insulin targets, resulting in high expression of ROS, activatio...

Claims

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Application Information

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Patent Type & Authority Patents(China)
IPC IPC(8): A61K36/8994A61P19/06A61P13/12A61P19/02
CPCA61K36/36A61K36/42A61K36/716A61K36/8945A61K36/8994A61K2236/331A61P13/12A61P19/02A61P19/06A61K2300/00
Inventor 张磊魏莉张瑾王健英
Owner SHANGHAI UNIV OF T C M
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