25 results about "Coix lacryma" patented technology

The application discloses a mulberry leaf astringency removing treatment process and super-micro powder thereof. The process mainly uses a fermented coix as an astringency removing agent to remove the astringency of frost mulberry leaves in combination with three steaming and hot air drying methods. The application solves the problems of astringency and green smell of the mulberry leaves by using a relatively simple process, retains the unique taste and fragrance of the mulberry leaves, and adds unique alcohol and ester fragrance, so that the taste and smell of the mulberry leaves are rich in layers. The prepared astringency removed mulberry leaf super-micro powder has high retention rate of main nutritional components, has obvious inhibition effect on alpha-glucosidase and pancreatic lipase, and can be used as a food base to develop health food for reducing blood sugar and blood fat.

The invention belongs to the field of traditional Chinese medicine, and particularly relates to a traditional Chinese medicine composition and a preparation and application thereof. A compatibility system of monarch, minister, assistant and guide is adopted, rhizoma atractylodis, semen coicis and cortex phellodendri are taken as monarch drugs, polygonum cuspidatum, centella asiatica and fructus kochiae are taken as minister drugs, prepared rheum officinale, radix achyranthis bidentatae and caulis spatholobi are taken as guide drugs, gynostemma pentaphyllum, radix paeoniae alba and rhizoma polygonati are taken as adjuvant drugs, the medicinal materials are compounded according to a specific mass ratio, and the mass ratio of the monarch drugs to the minister drugs to the adjuvant drugs to the guide drugs is (50-80): (50-80): (30-55): (35-70). The traditional Chinese medicine composition provided by the invention can remarkably reduce the levels of blood uric acid, serum creatinine and urea nitrogen, reduce urine protein excretion and improve inflammation, a hypercoagulation state and lipid metabolism disorder, the total effective rate reaches 90%, the adverse reaction is slight, and the recurrence rate is low.

The invention relates to the technical field of traditional Chinese medicine compositions, in particular to a novel astragalus membranaceus and poria cocos pill composition and a production process thereof. The raw materials comprise the following components: astragalus membranaceus, codonopsis pilosula, poria cocos, radix angelicae, platycodon grandiflorum, liquorice, red dates, coix seeds, grape seeds, black sesame and spina date seeds. The traditional Chinese medicine composition comprises the following raw material components in parts by mass: 10-20 parts of astragalus membranaceus, 8-15 parts of codonopsis pilosula, 10-18 parts of poria cocos, 5-12 parts of radix angelicae, 6-14 parts of platycodon grandiflorum, 3-8 parts of liquorice, 8-16 parts of red dates, 10-20 parts of coix seeds, 5-10 parts of grape seeds, 8-15 parts of black sesame and 6-12 parts of spina date seeds. The invention has the following beneficial effects: shape optimization: 3-5mm pills are prepared, the pill is convenient to take, the dosage is easy to control, and compared with decoction and powder, the pill is more convenient to store and carry; the production process is simple, parameters of each step are clear, large-scale production can be realized by adopting conventional traditional Chinese medicine processing equipment, and the production cost is relatively low; and the quality is stable: by strictly controlling raw material moisture, crushing granularity, mixing uniformity and finished product drying parameters, the finished product is stable in quality and long in validity period.

This invention discloses a spleen-strengthening and stomach-nourishing health tea and its preparation method, relating to the field of health tea. By weight, it is composed of the following raw materials: 12-18 parts of Euryale ferox, 10-15 parts of lotus seeds, 15-20 parts of Dioscorea opposita, 8-12 parts of Poria cocos, 3-5 parts of mulberry leaves, 2-3 parts of Coix lacryma-jobi, 2-4 parts of mulberry fruit, 1-2 parts of Cassia tora, 4-7 parts of Phyllanthus emblica, and 0.5-1.0% of roasted glutinous rice flour and 1.0-2.0% of ultrafine Poria cocos powder, accounting for 1.0-2.0% of the total weight of the above raw materials. This invention incorporates mulberry leaves, coix seeds, mulberries, cassia seeds, and amla seeds, and through a sophisticated combination of principal, assistant, and adjuvant herbs, leverages the clearing and unblocking properties of mulberry leaves and the spleen-strengthening and dampness-removing properties of coix seeds to create a significant synergistic effect with the ingredients of the Four Gods Decoction, greatly enhancing the core effects of strengthening the spleen and stomach, and solidifying the intestines to stop diarrhea. At the same time, mulberries and cassia seeds make the tea's effects mild, suitable for people with spleen and stomach deficiency and cold, as well as those with weak spleen and stomach accompanied by mild yin deficiency or damp heat, for long-term consumption.

The invention provides an edible and medicinal dual-purpose traditional Chinese medicine composition for delaying the pulmonary fibrosis process as well as a preparation method and application thereof, and relates to the technical field of traditional Chinese medicines. The traditional Chinese medicine composition provided by the invention is prepared from the following raw materials in parts by weight: 1-3 parts of platycodon grandiflorum and 3-8 parts of coix seeds. The food therapy method is used for treating the pulmonary fibrosis, the pulmonary fibrosis can be effectively cured, and the food therapy method is safe and non-toxic. In addition, the traditional Chinese medicine composition has few medicines, is convenient to obtain, has a better curative effect than any single medicine in the composition, and is clear in treatment mechanism. Experiments prove that treatment is carried out from mechanisms of different stages of pulmonary fibrosis, and the effect of staged intervention is achieved.

This invention relates to ClDGAT2, a gene related to oil synthesis in Job's tears, and its applications, belonging to the field of molecular biology. On one hand, this invention provides ClDGAT2, a gene related to oil synthesis in Job's tears, and its point-to-point mutant gene ClDGAT2T; on the other hand, it provides the application of the above genes in regulating plant oil accumulation. This invention is the first to transiently express ClDGAT2 and ClDGAT2T in tobacco leaves, finding that ClDGAT2T resulted in greater total oil production in tobacco leaves than ClDGAT2, indicating that in plants, mutating alanine (A) at amino acid position 204 of ClDGAT2 to serine (S) can enhance its oil synthesis capacity.

The invention discloses a traditional Chinese medicine composition for conditioning consumptive disease syndrome and application of the traditional Chinese medicine composition. The traditional Chinese medicine composition is prepared from 15-20 parts of astragalus membranaceus, 12-15 parts of radix pseudostellariae, 10-15 parts of poria cocos, 10-20 parts of Chinese yam, 10-20 parts of gordon euryale seeds, 5-15 parts of coix seeds, 5-15 parts of black sesame seeds and 10-15 parts of lotus seeds. The traditional Chinese medicine composition is reasonable in compatibility aiming at the core pathogenesis of the consumptive disease syndrome, radix astragali and radix pseudostellariae are taken as monarch drugs, Chinese yam, gordon euryale seed, lotus seed and black sesame are taken as ministerial drugs, poria cocos and coix seed are taken as adjuvant drugs, all the drugs have a synergistic effect, and the traditional Chinese medicine composition has the main effect of strengthening body resistance and the auxiliary effect of eliminating evil, tonifies qi and nourishes yin, and harmonizes upper jiao, middle jiao and lower jiao together (radix astragali and radix pseudostellariae regulate upper jiao, poria cocos, Chinese yam and lotus seed regulate middle jiao and lower jiao); gordon euryale seed and black sesame can regulate lower jiao, repair viscera functions, strengthen spleen and clear damp, prevent stagnation of nourishing, solve the contradiction of'stagnation of tonifying medicine to spleen ', regulate medicine properties, balance dryness of warm tonifying medicine through rhizoma nardostachyos and dryness moistening products, and avoid'attacking and hurting body resistance'.

This invention discloses a traditional Chinese medicine composition for regulating sub-health conditions and its preparation method, belonging to the technical field of traditional Chinese medicine compositions. This composition is made from a specific weight ratio of raw materials including Asparagus cochinchinensis, Lilium brownii, Poria cocos, Triticum aestivum, Polygonatum sibiricum, Morus alba, Black sesame, Walnut, Ginseng, Lycium barbarum, Angelica dahurica, Rose, Jujube, Honey, Citrus medica, Tangerine peel, Lotus seed, Prunus persica, Amomum villosum, Chrysanthemum morifolium, Hawthorn, Dioscorea opposita, Pueraria lobata, and Coix lacryma-jobi, with optional addition of natural Vitamin C. Based on the principles of traditional Chinese medicine (TCM) theory of monarch, minister, assistant, and guide herbs, this invention has the effects of invigorating Qi and nourishing Yin, strengthening the spleen and removing dampness, soothing the liver and regulating Qi, nourishing blood and calming the mind, and moisturizing the skin and beautifying the complexion. It effectively improves sub-health symptoms such as insomnia, fatigue, loss of appetite, and excessive dampness. This invention is suitable for people with difficulty swallowing and those requiring rapid onset of action. All dosage forms maintain the characteristics of mild medicinal properties, safety without side effects, simple preparation, and convenient administration, making it suitable for long-term daily conditioning and showing good application prospects.

This invention relates to a traditional Chinese medicine composition for treating chronic cervicitis complicated with HPV infection. The composition is made from the following raw materials in parts by weight: 26-34 parts raw Astragalus membranaceus, 26-34 parts Smilax glabra, 11-19 parts Toona sinensis root bark, and 26-34 parts raw Coix lacryma-jobi. This invention also provides the uses of the traditional Chinese medicine composition. In this invention, raw Astragalus membranaceus is the principal ingredient, tonifying Qi and strengthening the body's resistance; Smilax glabra and Toona sinensis root bark clear heat and dry dampness; and raw Coix lacryma-jobi dispels dampness and promotes tissue regeneration, serving as assistant ingredients; the entire formula works synergistically to strengthen the body's resistance, eliminate pathogenic factors, and promote tissue regeneration.

The invention belongs to the technical field of traditional Chinese medicine, and particularly relates to paste for benefiting qi and nourishing blood and a preparation method and application thereof. The qi-tonifying and blood-nourishing paste is prepared from a preparation A and a preparation B, namely donkey-hide gelatin and deer-horn glue, the preparation A comprises the following raw materials: radix hedysari, roasted rhizoma atractylodis macrocephalae, poria cocos, ligusticum wallichii, angelica sinensis, radix rehmanniae, radix rehmanniae preparata, spina date peel, bran-fried pericarpium citri reticulatae, semen boitae, fructus lycii and honey-fried licorice root; and the preparation B comprises the following raw materials: fried coix seeds, codonopsis pilosula, radix paeoniae alba, raw Chinese yams, light wheat, salvia miltiorrhiza, dendrobe and achyranthes bidentata. The invention discloses a traditional Chinese medicine ointment for reinforcing qi, nourishing blood and nourishing liver and kidney. The traditional Chinese medicine ointment overcomes the problems that in the prior art, a traditional Chinese medicine prescription for treating various diseases caused by qi-blood deficiency and liver and kidney deficiency is poor in taste, inconvenient to take and unstable in effective component absorption. Secondly, the traditional decoction is improved into the ointment, so that the traditional Chinese medicine has the advantages of being good in taste and convenient to carry and take, and the synergistic curative effects of reinforcing qi, nourishing blood and nourishing liver and kidney are remarkably enhanced.

The application discloses a traditional Chinese medicine composition and a preparation method and application thereof. The traditional Chinese medicine composition is composed of the following raw materials in a weight ratio: Houttuynia cordata: Coix seed: Ardisia japonica: Cycas leaf = 10:10:10:3. The preparation method comprises the following steps: accurately weighing Houttuynia cordata 30g, Coix seed 30g, Ardisia japonica 30g and Cycas leaf 9g according to a proportion of 10:10:10:3, mixing the Coix seed, the Ardisia japonica and the Cycas leaf in 2000ml of water to decoct, putting the Houttuynia cordata into the water to be boiled on a strong fire and then to be decocted on a weak fire for 1000ml, filtering out medicinal dregs, and preparing Houttuynia cordata-Coix seed soup with a mother liquor concentration of 9.9% and low-temperature freezing preservation. The application determines specific formula and proportion, deeply studies the action mechanism of the four raw medicinal materials of Houttuynia cordata, Coix seed, Ardisia japonica and Cycas leaf in the treatment of LUAD, and provides a new treatment idea and direction for the traditional Chinese medicine treatment of LUAD.

This invention belongs to the field of traditional Chinese medicine, specifically relating to a traditional Chinese medicine composition for treating low anterior rectal resection syndrome and its uses. By weight, the traditional Chinese medicine composition consists of 18-30 parts of Atractylodes macrocephala, 12-18 parts of Atractylodes lancea, 12-18 parts of Coix lacryma-jobi, 18-30 parts of Poria cocos, 12-20 parts of Galla chinensis, 12-16 parts of Scutellaria baicalensis, 20-30 parts of Paeonia lactiflora, 9-12 parts of Mentha haplocalyx, 9-18 parts of Astragalus membranaceus, 12-18 parts of Pulsatilla chinensis, 12-18 parts of Prunus mume, 12-18 parts of Cimicifuga foetida, 10-15 parts of Phellodendron chinense, and 10-16 parts of Paeonia lactiflora. These fourteen herbs work together to tonify the spleen and stomach, clear damp-heat, and astringe the intestines, and can be used to prepare a medicine for treating low anterior rectal resection syndrome.

This invention belongs to the field of traditional Chinese medicine technology, specifically relating to a pharmaceutical composition for treating simple obesity of spleen deficiency and dampness retention type and its application. This pharmaceutical composition is prepared based on seven traditional Chinese medicines listed in the Food and Drug Catalogue: Codonopsis pilosula, Poria cocos, Coix lacryma-jobi, Dioscorea opposita, Nelumbo nucifera, Lilium brownii, and Ziziphus jujuba. The pharmaceutical composition provided by this invention improves the condition of swollen, pale, and white-coated tongue in rats with simple obesity of spleen deficiency and dampness retention type, and improves abnormal lipid metabolism; it can effectively regulate abnormalities in serum BUN, UA, MTL, VIP, and other indicators in rats with simple obesity of spleen deficiency and dampness retention type, improve gastrointestinal emptying, enhance gastrointestinal motility, and increase the calcium content of myocardial cell membranes. 2+ -ATPase, Na + -K + - It increases ATPase activity, improves cellular energy metabolism, and reduces the risk of cardiovascular disease caused by obesity; it inhibits the expression levels of BUN and UA, which can treat obesity-induced hyperuricemia and improve renal metabolism. It also exerts a therapeutic effect on simple obese rats with spleen deficiency and dampness retention.

The invention discloses a preparation method of coix lacryma-jobi grain stillage protein peptide-chitosan composite hemostatic gel. The preparation method comprises the following steps: modifying and extracting coix lacryma-jobi grain stillage protein peptide, preparing a composite base material dispersion liquid, constructing a cross-linking system, performing CBD-thrombin non-covalent anchoring, and performing gel forming to finally obtain the composite hemostatic gel. Rapid hemostasis is achieved through double mechanisms of physical capture and chemical activation, the method is suitable for high-pressure and irregular wounds, and the defect that pure chitosan is prone to collapsing is overcome; the biocompatibility is good, the anti-inflammatory function and the repair promoting function are achieved, and hemostasis and repair integration is achieved.

Baikal skullcap root, white paeony root and sophora flower are supplemented in a formula of coix lacryma-jobi radix aconiti carmichaeli patrinia powder in a pharmacopoeia, the proportion of the formula is optimized, the yang warming and body resistance strengthening effects of radix aconiti carmichaeli are reserved, and meanwhile the relative proportion of radix aconiti carmichaeli in the total formula is reduced through compatibility optimization; radix scutellariae, radix paeoniae alba and flos sophorae which have the effects of clearing away heat and toxic materials and relieving spasm and pain are used for enhancing anti-inflammatory and colon repairing effects. Aiming at the inflammatory bowel disease, the equivalent or better curative effect of the high-dose pharmacopoeia coix lacryma-jobi radix aconiti carmichaeli patrinia powder is achieved under the condition of lower crude drug administration dosage, the potential safety risk is reduced, and the composition is more suitable for long-term maintenance treatment and relapse prevention.

The present application relates to the technical field of functional food preparation and development of resources of medicinal and edible origin, and specifically relates to a compound lipid-lowering functional tablet candy of coix seed and red koji and a preparation method thereof. The present application realizes the synergistic promotion of active ingredient enrichment, stable processing characteristics and efficient lipid-lowering effect through precise control of the solid-state fermentation process of coix seed by Monascus purpureus and formula optimization based on the AHP-CRITIC mixed weighting method. The content of lovastatin in the tablet candy of the present application is 1.35 times that of the same type of commercially available red koji product, the content of phytosterols (especially ergosterol) is more than 4 times that of commercially available products, and the product retains the coixol component that is not detected in commercially available products. The raw materials of the present application are all resources of medicinal and edible origin or food-grade auxiliary materials, and have high long-term safety. The tablet candy has high standardization, is easy to take and store stably, and meets the convenience needs of consumers for daily health management.

The application discloses a coix salt stress resistance related gene ClWRI1-20 and application thereof, and belongs to the technical field of molecular biology.The application provides the coix salt stress resistance related gene ClWRI1-20 and the coding protein thereof, and provides the use of the coix salt stress resistance related gene ClWRI1-20.The application provides an important and possibly universal gene resource for regulating coix salt stress resistance, and provides an excellent candidate gene for cultivating plant varieties with stress resistance.

The invention belongs to the technical field of plants, and particularly relates to a coix phytoene dehydrogenase ClPDS gene and a construction method of a VIGS silencing system. The invention provides a coix phytoene dehydrogenase ClPDS gene. The nucleotide sequence of the coix phytoene dehydrogenase ClPDS gene is as shown in SEQ ID No. 1; silencing a specific fragment of the coix phytoene dehydrogenase ClPDS gene, wherein the specific fragment is a fragment I, a fragment II or a fragment III; the nucleotide sequences of the fragment I, the fragment II and the fragment III are respectively shown as SEQ ID No. 2, SEQ ID No. 3 and SEQ ID No. 4. After the specific fragment is silenced, carotenoid conversion is inhibited, chlorophyll loses protection of carotenoid, chlorophyll can be destroyed by strong light for green removal, and finally, an obvious photobleaching phenomenon appears at a silenced part in a phenotype.

The invention provides a method for measuring coixol by high performance liquid chromatography, which comprises the following steps: taking a coixol standard substance and a to-be-measured sample containing coixol, respectively preparing a reference substance solution and a test solution by taking methanol as a solvent, then precisely sucking the reference substance solution and the test solution and respectively injecting into a high performance liquid chromatograph, chromatographic conditions are as follows: a C18 chromatographic column is adopted, the flow velocity is 1mL / min, the sample size is 20mu L, the column temperature is 25 DEG C, the detection wavelength is 232nm, the mobile phase is acetonitrile-0. 1% phosphoric acid aqueous solution (V: V = 65: 35), and the content of coixol in the test sample is measured. According to the method, the parameters of the mobile phase are changed aiming at the prior art, the peak height and the peak area are not obviously influenced after testing, but the peak appearance time is greatly shortened, so that the testing speed is accelerated, and the efficiency is improved.

The invention discloses a coix by-product low-protein daily ration formula and application, and belongs to the field of animal feed. The daily ration comprises 3%-15% of fermented coix lacryma-jobi functional components, a plurality of amino acids, a complex enzyme preparation and the balance of a nutrient substrate. The fermented coix lacryma-jobi functional component is prepared from coix lacryma-jobi roots, stems and leaves through solid fermentation of stropharia rugoso-annulata. Through a biological fermentation and amino acid balance technology, the crude protein content of the daily ration is reduced to 13.5%-15.5%. According to the formula, the feed-gain ratio and excrement nitrogen emission can be reduced while the growth performance of growing pigs is guaranteed, resource utilization of agricultural by-products is facilitated, the breeding cost is reduced, and the environment is protected.

This invention discloses a traditional Chinese medicine composition for dissolving nodules and tumors, its preparation method, and its application. The composition comprises the following components in parts by weight: 4-8g of *Taxus wallichiana*, 20-40g of *Actinidia chinensis* root, 5-25g of *Lobelia chinensis*, 20-40g of *Scutellaria barbata*, 20-40g of *Hedyotis diffusa*, 1-5g of *Scolopendra subspinipes*, 5-15g of *Curcuma zedoaria* (processed with vinegar), 5-25g of *Solanum lyratum*, 20-40g of *Astragalus membranaceus*, 5-15g of *Angelica sinensis*, 5-25g of *Pseudostellaria heterophylla*, 5-25g of *Poria cocos*, 5-25g of *Atractylodes macrocephala* (stir-fried with wheat bran), 20-40g of *Coix lacryma-jobi*, 5-15g of *Pinellia ternata* (processed with ginger), 5-15g of *Citrus reticulata* peel, and 5-15g of *Glycyrrhiza uralensis*. This formula combines tonification and purgation, nourishing qi and blood, regulating the spleen and stomach, and dissolving nodules and tumors. This invention, through the addition and subtraction of prescription drugs, can dissolve nodules and eliminate tumors in the early stage of gastric and intestinal tumor treatment, while protecting the spleen and stomach's qi and blood; in the middle stage of gastric and intestinal tumor treatment, it can strengthen the spleen, resolve dampness, detoxify and disperse nodules, combining attack and tonification; in the terminal stage of gastric and intestinal tumor treatment, it can invigorate qi and support the body's resistance, while also having anti-cancer effects.

The invention relates to the field of traditional Chinese medicines and foods, in particular to a composition (traditional Chinese medicine with homology of medicine and food) with functions of resisting anxiety and depression and improving sleep and application of the composition. The composition comprises the following traditional Chinese medicine decoction pieces in parts by weight: 1-6 parts of fingered citron, 0.5-4 parts of rose, 1-6 parts of codonopsis pilosula, 1-6 parts of poria cocos, 1-6 parts of fried coix seed, 0.5-4 parts of pericarpium citri reticulatae, 1-6 parts of spina date seed (fried) and 0.5-2 parts of liquorice (roasted). The preparation method comprises the following steps: independently extracting the natural medicines or mixing the natural medicines, extracting with water, performing spray drying on an extracting solution to prepare powder, and uniformly mixing the powder to prepare a concentrated product. The components of the aqueous extract have a synergistic effect, and the aqueous extract can well improve the mild anxiety symptom and improve the sleep quality. Meanwhile, all the components are natural products with homology of medicine and food, are safe and free of side effects, and can be directly added into various food formulas to play a health-care role.

This invention discloses a traditional Chinese medicine composition for the prevention and / or treatment of gastric ulcers and / or their complications. By weight, the composition comprises: 2-6 parts of Atractylodes lancea, 2-6 parts of Poria cocos, 1-4 parts of Magnolia officinalis, 2-6 parts of Aucklandia lappa, 1-4 parts of Lindera strychnifolia, 1-4 parts of Cyperus rotundus, 1-4 parts of Alpinia officinarum, 1-4 parts of Amomum villosum, 1-4 parts of Coix lacryma-jobi, 1-4 parts of Citrus reticulata peel, 1-4 parts of Citrus medica, 1-4 parts of Crataegus pinnatifida, 1-4 parts of Massa fermentata, 1-4 parts of Hordeum vulgare, 1-4 parts of Gallus gallus domesticus gizzard lining, 1-4 parts of Bletilla striata, 2-6 parts of Paeonia lactiflora, 2-6 parts of Corydalis yanhusuo, 1-4 parts of Cinnamomum cassia, and 1-4 parts of Piper longum. The complications are selected from one or more of the following: pain, inflammation, and delayed gastric emptying. This traditional Chinese medicine composition is safe, effective, and has a simple and efficient preparation method with controllable quality. It exhibits significant anti-inflammatory, analgesic, and gastric motility-promoting effects, and can reduce the colonization of Helicobacter pylori in the stomach. It also has significant therapeutic effects on gastric ulcers induced by different factors (Helicobacter pylori infection, pyloric ligation, and nonsteroidal anti-inflammatory drugs).

The invention discloses a traditional Chinese medicine composition for treating adolescent hyperuricemia. The traditional Chinese medicine composition comprises the following components in parts by weight: 1-1.5 parts of astragalus membranaceus, 1-3 parts of Chinese yam, 0.5-1 part of golden cypress, 1 part of rhizoma atractylodis, 0-1 part of bighead atractylodes rhizome, 1 part of radix rehmanniae, 2-3 parts of rhizoma smilacis glabrae, 0-1 part of radix saposhnikoviae, 1-2 parts of rhizoma alismatis, 0-3 parts of coix seeds, 1 part of hawthorn, 0-1.5 parts of lotus leaves, 1-3 parts of corn stigma, 0-1 part of chrysanthemum and 0.5-1 part of liquorice. According to the main treatment principles of tonifying qi, strengthening spleen, resolving dampness and removing turbidity, various medicinal and edible traditional Chinese medicinal materials are adopted, through clinical verification and animal experiments, the curative effect is definite, the treatment effect is good, the safety is high, and a scientific basis is provided for exploring a new strategy for treating teenager hyperuricemia through combination of traditional Chinese medicine and western medicine.

The invention discloses a traditional Chinese medicine composition for treating Crohn disease intestinal fibrosis as well as a preparation method and application of the traditional Chinese medicine composition. The traditional Chinese medicine composition is prepared from the following raw materials in parts by weight: 6-18 parts of codonopsis pilosula, 6-18 parts of bighead atractylodes rhizome, 1-6 parts of coptis chinensis, 9-24 parts of Chinese yam, 9-24 parts of dahurian patrinia herb, 5-15 parts of rhizoma atractylodis, 5-15 parts of pericarpium citri reticulatae, 5-15 parts of lotus plumule, 9-24 parts of red paeony root, 9-24 parts of hairyvein agrimony, 5-15 parts of turtle shell, 5-15 parts of cassia twig, 9-24 parts of poria cocos, 6-18 parts of peach kernel, 5-15 parts of moutan bark, 5-15 parts of dendrobe, 5-15 parts of selaginella tamariscina and 12-30 parts of coix seed. Aiming at the clinical problem of fibrous stenosis formed after inflammation control, the traditional Chinese medicine composition disclosed by the invention adopts a treatment method of tonifying spleen and drying dampness, clearing heat and removing turbidity, promoting blood circulation to remove blood stasis and softening hardness to dissipate stagnation, and is scientific in formula. Network pharmacology prediction and experimental verification show that the compound can regulate and control the fibrosis process in a multi-target manner, remarkably reverse the formed intestinal fibrosis and improve the intestinal elasticity, is good in long-term medication safety, and provides an effective traditional Chinese medicine solution for treating the Crohn disease intestinal fibrosis.