Diffusion-weighted imaging method

A technology of diffusion weighted imaging and diffusion coefficient, applied in image enhancement, image analysis, image data processing, etc., can solve problems such as complex calculation methods, achieve improved signal-to-noise ratio, improve the reliability of parameter estimation, and ensure non-negativity Effect

Active Publication Date: 2017-10-10
SHANGHAI UNITED IMAGING HEALTHCARE
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However, some of these methods require additional data sampling and averaging, and some req

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[0034] In order to make the above objects, features and advantages of the present invention more obvious and comprehensible, specific implementations of the present invention will be described in detail below in conjunction with the accompanying drawings and embodiments.

[0035] Such as figure 1 As shown, the diffusion weighted imaging method of the present invention mainly includes:

[0036] S10. Using a magnetic resonance scanner to acquire multiple b-value DWI images of the subject. The random movement of water molecules in the medium is called diffusion. When the gradient magnetic field exists, the diffusion of water molecules will cause the dephasing of the transverse magnetization vector and cause the MR signal to decrease. DWI can observe the diffusion characteristics of water molecules. In order to increase the sensitivity of diffusion, it is necessary to apply a diffusion sensitive gradient. The applied diffusion sensitive gradient can be compared with spin echo (sp...

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Abstract

The invention discloses a diffusion-weighted imaging method comprising the following steps: a plurality of b-value DWI images of a testee are collected via a magnetic resonance scanner, and noise reduction operation is performed on the DWI images via an SVD-PCA-based method; after the noise reduction operation, the DWI images are obtained and subjected to non-linear fitting operation, and estimated parameters of noncoherent motion in voxel can be obtained; the parameters comprise true diffusion coefficients, false diffusion coefficients and perfusion scores. According to the diffusion-weighted imaging method, after singular values of a vector composite matrix are filtered, noise components of the DWI images can be effectively removed; a signal to noise ratio can be improved, and therefore reliability of the estimated parameters of the noncoherent motion in the voxel can be improved.

Description

【Technical field】 [0001] The invention relates to the technical field of magnetic resonance imaging, in particular to an incoherent motion diffusion weighted imaging method within a voxel. 【Background technique】 [0002] Diffusion weighted imaging (DWI) belongs to the category of functional imaging, and is currently the only imaging method for measuring the diffusion movement of water molecules in tissues in vivo. It can reflect the microstructure of human tissues, the transfer of water molecules inside and outside cells, transmembrane movement, and changes in temperature. The qualitative comparison of DWI image signal level and the quantitative measurement of apparent diffusion coefficient (ADC) can be used to evaluate the changes in tissue structure and function, which can be used to display the sensitivity of the disease, diagnosis and differential diagnosis. [0003] In the traditional diffusion theory, the displacement movement of water molecules diffusing from one par...

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Application Information

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IPC IPC(8): G06T7/30G06T11/00
CPCG06T7/0012G06T11/003G06T2207/10088G06T2207/30016
Inventor 何任杰刘琦丁彧
Owner SHANGHAI UNITED IMAGING HEALTHCARE
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