Animal cold stress test device

An experimental device and cold stress technology, applied in the direction of animal restraint equipment, application, medical science, etc., can solve problems such as disability and joint deformation, save experimental time, improve experimental efficiency, improve adaptability and flexibility of use sexual effect

Pending Publication Date: 2017-11-10
WUXI HOSPITAL OF CHINESE MEDICINE
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  • Abstract
  • Description
  • Claims
  • Application Information

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Problems solved by technology

This inflammation can deform the

Method used

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Embodiment Construction

[0018] The present invention will be described in detail below in conjunction with the implementations shown in the drawings, but it should be noted that these implementations are not limitations of the present invention, and those of ordinary skill in the art based on the functions, methods, or structural changes made by these implementations Equivalent transformations or substitutions all fall within the protection scope of the present invention.

[0019] Such as Figure 1-4 The animal cold stress experimental device shown includes a controller 8, a test bench 7, a water storage room a, a water storage room b, a water storage room c and a water storage room d, a water storage room a, a water storage room b, a water storage room The water chamber c and the water storage chamber d are separated by a separation plate 10 . In this embodiment, the animal is preferably a mouse.

[0020] The water storage chamber a, water storage chamber b, water storage chamber c and water stora...

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Abstract

The invention provides an animal cold stress test device, which comprises a test table, a plurality of mutually isolated water storage chambers and compressors, wherein the compressors communicate with the water storage chambers; a fixing device used for fixing an animal body is arranged on the test table; each water storage chamber is provided with an accommodating part for accommodating animal branch legs; a temperature detector is arranged in each water storage chamber; the animal cold stress test device also comprises a controller electrically connected with the compressors and the temperature detectors; each temperature detector transmits the detected temperature to the controller; and the controller controls whether the compressors work or not by comparing the received temperature with the preset temperature. The animal cold stress test device has the advantages that the plurality of mutually isolated water storage chambers are arranged; the accommodating part for accommodating animal legs is arranged in each water storage chamber; the fixing device used for fixing the animal body is arranged on the test table, so that the cold stress response of different legs of the same mouse to different external temperatures in the same time can be tested; the adaptability and the use flexibility of the animal cold stress test device are improved; the test time is saved; and the test efficiency is improved.

Description

technical field [0001] The invention relates to the technical field of cold stress experiment devices, in particular to animal cold stress experiment devices. Background technique [0002] Rheumatoid arthritis (RA) is a chronic autoimmune disease characterized by joint synovitis, often accompanied by invasion of inflammatory cells (T cells, neutrophils, macrophages, etc.), microvascular proliferation, Pathological changes such as hyperplasia of joint synoviocytes, thickening of the subsynovial synovium to form villous protrusions, and cartilage damage. This inflammation can deform and disable the joint. RA is ubiquitous in the world, according to statistics, the prevalence rate is about 1-2% in the world, and the prevalence rate in my country is about 0.5%. [0003] Temperature is an important factor in inducing rheumatoid arthritis. Therefore, exploring the effect of external temperature on the induction of rheumatoid arthritis in humans is the only way to effectively pre...

Claims

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Application Information

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IPC IPC(8): A61D1/00A61D3/00
CPCA61D1/00A61D3/00A61B2503/40
Inventor 华臻王建伟杨俊峰陆振飞王善付
Owner WUXI HOSPITAL OF CHINESE MEDICINE
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