Antibacterial and hemostatic ointment, antibacterial and hemostatic medicine and preparation methods of antibacterial and hemostatic ointment and antibacterial and hemostatic medicine
The technology of ointment and Panax notoginseng is applied in the field of antibacterial hemostatic ointment, medicine and preparation thereof, which can solve the problems of secondary injury to users, poor bacterial inhibition ability, poor air permeability, etc. Effect
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Embodiment 1
[0027] A preparation method of antibacterial hemostatic ointment includes the following steps:
[0028] (1) Wash Panax notoginseng, cornel, Polygala, licorice, aloe, milk thistle, and sorrel beans with a mass ratio of 100:48:24:39:61:36:13 and add them to pure water and soak for 30 minutes. Ratio 1:25; then take out the cleaned Panax notoginseng, cornus, Polygala, licorice, aloe, silybum, and sorrel bean after microwave drying; then use water as the extract to hydrate Panax notoginseng, cornus, Polygala, and licorice. The extraction process obtains the Panax notoginseng water extract, the cornel water extract, the Polygala water extract, and the licorice water extract; using the ethanol as the extract, the milk thistle and the bitter bean are subjected to the ethanol extraction process to obtain the milk thistle ethanol extract, Sophora flavescens ethanol extract; Aloe is extracted with a mixture of Panax notoginseng water extract and Silybum marianum ethanol extract to obtain Pa...
Embodiment 2
[0032] An antibacterial hemostatic ointment sheet, including the antibacterial hemostatic ointment of Example 1 and a mop; see attached Figure 1-3 , The mop includes a lining layer 1, two lining strips 2, a graphene fiber layer 3, an ointment adsorption network layer 4, and a bonding layer 5 connected in sequence. The thickness of the laminating layer is 0.3 microns, and a number of vents 6 are evenly distributed in the thickness direction. Each vent 6 penetrates the laminating layer 5 so that the ointment adsorption mesh layer 4 and the outside can pass through the The ventilation holes 6 are connected. The two lining strips 2 are arranged horizontally at intervals between the lining cloth layer 1 and the graphene fiber layer 3. The graphene fiber layer is obtained by impregnating graphene with fibers, and is fixed on the front surface of the lining strip 2. 1 is fixed on the back of the strip 2. The graphene fiber layer 3 includes two ends 30 and a middle portion 31. The mi...
Embodiment 3
[0034] An antibacterial hemostatic drug prepared by the following method. The antibacterial hemostatic ointment of Example 1 was mixed with a pH 8 disodium hydrogen phosphate-sodium hydroxide buffer at a mass ratio of 2:1, and ultrasonically dispersed for 2 hours; then added The hyaluronic acid of 5% by mass of the ointment was ultrasonically dispersed for 10 minutes to obtain an antibacterial hemostatic drug.
[0035] The count showed that its 24-hour sterilization rate for Escherichia coli was 99.95%, the 24-hour sterilization rate for Staphylococcus aureus was 99.93%, the 24-hour sterilization rate for Candida albicans was 99.94%, and the 24-hour killing rate for L929 was 7%; total Antioxidant capacity is 994U / g; the hemostasis time for a 1 cm wound (volunteer) in human forearm is 20 to 30 seconds, 3 people.
[0036] New Zealand rabbits, weighing about 2.6kg, were randomly divided into a blank control group and a treatment group, 2 in each group. Pentobarbital was injected into ...
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