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Cosmetic composition

A technology of composition and extract, which is applied in the field of composition to improve the visual appearance of skin, and can solve problems such as long recovery period and skin irritation

Inactive Publication Date: 2017-12-12
MARY KAY INC
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0003] Previous attempts to improve the visual appearance of the skin using known skin active ingredients have been shown to have various drawbacks such as skin irritation and long recovery periods

Method used

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  • Cosmetic composition
  • Cosmetic composition
  • Cosmetic composition

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0085] A formulation with ingredients from Example 1 was prepared as a facial mask. The formulations in Table 1 were prepared as exfoliating masks. The formulations in Table 2 were prepared as repairing or exfoliating masks.

[0086] Table 1

[0087]

[0088]

[0089] **Excipients are added to modify the rheology of the composition. Alternatively, the amount of water may vary so long as the amount of water in the composition is at least 40% by weight, preferably 45% to 65% by weight.

[0090] Table 2

[0091]

[0092] **Excipients are added to modify the rheology of the composition. Alternatively, the amount of water may vary so long as the amount of water in the composition is at least 15%, preferably 25% to 85% by weight.

Embodiment 2

[0094] Increases involucrin present in epidermal keratinocytes:

[0095]Involucrin is a differentiation protein that plays an important role in skin regeneration. ELISA was used to analyze the effect of components on involucrin production by human epidermal keratinocytes. This paper discloses that Mucor miehei extract (ACTIZYME TM ), sugar isomers (Benoiderm), Bacillus fermentation product (KERATOLINE TM ), and nopal cactus flower extract (EXFOLACTIVE TM ) increased the involucrin content of human epidermal keratinocytes (Table 3).

[0096] table 3

[0097] Element

concentration

Increased involucrin %

ACTIZYME TM (Mucor miehei Extract)

2％

7.7％

Benoiderm (sugar isomers)

1％

108％

KERATOLINE TM (Bacillus ferment product)

2％

84％

EXFOLACTIVE TM (Nopal cactus flower extract)

4％

84％

[0098] Briefly, at 37°C in 5% CO 2 Subconfluent normal human mature keratinocytes (Cascade Biologics) cultured in E...

Embodiment 3

[0101] Clinical increase in skin regeneration / renewal / exfoliation

[0102] Increased skin regeneration / renewal / exfoliation can reduce the signs of aging and improve the skin's visual appearance. In clinical studies, Mucor miehei extract (ACTIZYME TM ), Bacillus fermentation product (KERATOLINE TM ) and nopal cactus flower extract (EXFOLACTIVE TM ) and Mucor miehei extract (ACTIZYME TM ), sugar isomers (Benoiderm) and Bacillus fermentation products (KERATOLINE TM ) combination each reduced the mean time to skin regeneration / renewal / exfoliation from 21.40 days to less than 14 days (Table 4).

[0103] Table 4

[0104]

[0105] Briefly, the regenerating / renewing / exfoliating effects of two combinations of ingredients were evaluated on the skin of 26 healthy adult female volunteers using DHA (dihydroxyacetone)-induced skin pigmentation. DHA was applied to the treated area on the volunteer's skin. Do not treat, apply 2% ACTIZYME TM (Mucor miehei extract), 4% EXFOLACTIVE T...

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Abstract

The invention relates to a cosmetic composition, and in particular discloses a composition and a method used for improving the visual appearance of the skin. In some aspects, the composition disclosed by the invention can comprise, for example, combined ingredients capable of removing keratin, reducing or eliminating irritation caused by keratin removal, renewing the skin, increasing skin regeneration, increasing skin luster, soothing the skin, or increasing the smoothness of the skin. The combination of the ingredients can be included in a wide range of product preparations (for example, essence, eye cream, toner, gel, masks, facial masks and the like).

Description

technical field [0001] The present invention generally relates to compositions and methods that can be used to improve the visual appearance of skin. In some aspects, the compositions disclosed herein can include, for example, for exfoliating, reducing or eliminating irritation due to exfoliation, renewing the skin, regenerating the skin, increasing skin radiance, soothing the skin, and / or increasing the smoothness of the skin. Combination of ingredients. Background technique [0002] Aging, chronic exposure to adverse environmental factors, nutritional disorders, fatigue, etc. can alter the visual appearance, physical properties or physiological functions of the skin in ways that are considered visually undesirable. The most noticeable and noticeable changes include the development of fine lines and wrinkles, loss of elasticity, increased sagging, loss of firmness, loss of color uniformity or tone, rough surface texture, and mottled pigmentation. Subtle but measurable cha...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K8/99A61K8/9789A61K8/60A61K8/365A61Q19/00A61Q19/02A61Q19/08
CPCA61Q19/00A61Q19/02A61Q19/08A61K8/365A61K8/602A61K8/97A61K8/99A61K8/06A61K8/9728A61K8/9789A61K2800/28A61K8/891A61K8/585A61K8/345A61K8/34A61K8/8182A61K8/73A61K8/8158A61K8/31A61K8/731A61K8/63A61K8/678A61K8/41A61K8/738A61K8/4993A61K8/44A61K8/4973A61K8/606
Inventor 大卫·甘吉赛·卡拉哈斯蒂利沙·万佩尔特
Owner MARY KAY INC
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