Preparation method and application of mesoporous SiO2/MoS2 material

Abstract

The invention provides a preparation method of a mesoporous SiO2 / MoS2 material. The preparation method comprises the following steps: step I, weighing mesoporous silicon dioxide, a sulfur source and a molybdenum source according to a given ratio; step II, ultrasonically dispersing the mesoporous silicon dioxide, the sulfur source and the molybdenum source in an ethanol aqueous solution, and obtaining uniform turbid solution; step III, rotating and centrifuging the uniform turbid solution under a vacuum condition, and obtaining precipitates; step IV, transferring the precipitates into a stainless steel reaction kettle, adding polyethylene glycol, sealing, and reacting to obtain a reaction product; step V, washing the reaction product by using a neovaricaine aqueous solution, then washing with distilled water, and obtaining mesoporous silicon dioxide loaded with MoS2; step VI, adding silane coupling agent into the ethanol solution with the mesoporous silicon dioxide loaded with the MoS2 under a water bath condition, stirring, reacting, and centrifuging to obtain the amino modified mesoporous SiO2 / MoS2 material; and step VII, dispersing the mesoporous SiO2 / MoS2 material into an aqueous solution, adding activated polyethylene glycol, reacting, and obtaining the completely modified stable mesoporous SiO2 / MoS2 material.

Description

technical field [0001] The invention relates to the field of biological nanomaterials, in particular to a mesoporous SiO 2 / MoS 2 Preparation methods of materials and their applications. Background technique [0002] In recent years, two-dimensional transition metal dichalcogenides (TMDs, such as MoS 2 Nanosheets) have shown good application prospects in the field of biomedicine, especially in the field of photothermal therapy of tumors. Photothermal ablation of tumors is a novel minimal / non-invasive approach to tumor treatment. Photothermal tumor ablation uses infrared laser (NIR, wavelength range: 700-1100nm) to irradiate the photothermal material enriched in the tumor tissue, the photothermal material absorbs and converts NIR into heat, which makes the tumor tissue heat up locally and leads to tumor ablation death , thereby killing tumor cells. [0003] The prerequisite for near-infrared light to play a therapeutic role in living organisms is the need for nanomateria...

AI Technical Summary

Problems solved by technology

However, the use of monodispersity of mesoporous SiO2, the flexibility of surface modification, and the study of photothermal materials MoS2 and chemotherapy drugs loaded on mesoporous channels have not yet been reported in literature and patents.

Images