Medicine for preventing hepatic fibrosis and preparation method of medicine

A technology of liver fibrosis, medicine, applied in the medical field

Inactive Publication Date: 2018-01-30
成都图瑞思舟科技有限公司
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0004] The invention provides a medicine for preventing liver fibrosis and a preparation method thereof, which solves the technical problem in the prior art that the key cells that directly inhibit the formation of fibrotic tissue are urgently needed

Method used

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  • Medicine for preventing hepatic fibrosis and preparation method of medicine
  • Medicine for preventing hepatic fibrosis and preparation method of medicine
  • Medicine for preventing hepatic fibrosis and preparation method of medicine

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Experimental program
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Embodiment Construction

[0014] In order to make the above objects, features and advantages of the present invention more comprehensible, the present invention will be further described in detail below in conjunction with the accompanying drawings and specific embodiments.

[0015] The embodiment of the present invention provides a medicine for preventing liver fibrosis, including: 13-20 parts of angelica extract, 8-13 parts of safflower extract, 5-10 parts of dried ginger, 9-18 parts of saponin fruit extract , 7-14 parts of Chuanxiong extract.

[0016] Wherein, the saponins fruit extract is the saponins aqueous extract AEG. The concentration of AEG of the saponins aqueous extract is 10 μM, 30 μM or 100 μM.

[0017] The following experiments specifically illustrate the therapeutic effect of the saponin locust aqueous extract on chemical or alcoholic liver fibrosis in rats and the effect on the proliferation and activation of hepatic stellate cells, as follows:

[0018] 1. Preparation of experimental...

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Abstract

The invention relates to technical field of medical treatment and discloses a medicine for preventing hepatic fibrosis and a preparation method of the medicine. The medicine is prepared from the following components: 13 to 20 parts of radix angelicae sinensis extract, 8 to 13 parts of safflower extract, 5 to 10 parts of rhizoma zingiberis, 9 to 18 parts of semen gleditsiae sinensis extract and 7 to 14 parts of rhizoma chuanxiong extract. The medicine for preventing the hepatic fibrosis, disclosed by the invention, has the abilities of reducing liver damage and subsequent fibrosis lesions caused by alcohol; a key cell, namely the hepatic stellate cell, formed by fibrosis tissues can be directly inhibited; in addition, by protecting the liver, liver damage, steatosis and inflammation causedby the alcohol are inhibited, thereby delaying the pathogenetic process of liver fibrosis.

Description

technical field [0001] The invention relates to the field of medical technology, in particular to a medicine for preventing liver fibrosis and a preparation method thereof. Background technique [0002] In recent years, with the development of social economy and the improvement of people's living standards, the consumption of various alcoholic beverages is also increasing day by day, and the incidence of alcoholic liver disease (ALD) caused by alcoholism increases accordingly. In China, ALD has become the second leading cause of liver disease after HBV infection, and the research on the pathogenesis, treatment methods and related drugs of ALD has gradually become a hot spot. ALD has a very typical pathogenesis. It usually manifests as fatty liver in the early stage, followed by fatty degeneration of the liver, and can develop into liver fibrosis and even cirrhosis in the later stage. [0003] Hepatic stellate cells (HSCs) play the most critical role in the pathogenesis of l...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/9068A61P1/16
Inventor 赖朋卓图强宋宏玉
Owner 成都图瑞思舟科技有限公司
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