Pharmacologically-active chitosan/ethyl cellulose long-acting spraying agent

Abstract

The invention belongs to the two technical fields such as medical preparations and medical devices, relates to new uses of a water dispersion technology in external application preparations, and discloses a pharmacologically-active chitosan / ethyl cellulose long-acting spraying agent and a preparation method thereof, wherein the components of the pharmacologically-active chitosan / ethyl cellulose long-acting spraying agent in the final solution comprise, by mass volume percentage, 0-5% of chitosan and derivative thereof, 0-10% of ethyl cellulose, 0.1-10% of an emulsifier, 0.1-10% of a plasticizer, 0.1-2% of a defoamer, 0-5% of an acid, a proper amount of a pH value adjusting agent, 0-10% of other non-essential excipients, and the balance of purified water. According to the present invention,the pharmacologically-active true film can be formed after the pharmacologically-active chitosan / ethyl cellulose long-acting spraying agent is sprayed onto the skin so as to achieve the beneficial effects of long acting, water resistance, friction resistance, wound healing promotion, scar formation reduction and spot concealing.

Description

Technical field [0001] The present invention can be applied to the two fields of the technical field of medical preparations and the technical field of medical devices, and relates to a new application of water dispersion technology applied to external preparations, and in particular to a chitosan / ethyl cellulose long with pharmacological activity Effective film spraying agent and its preparation method. Background technique [0002] Skin infections and skin injuries are common symptoms in life or clinically. Conventional skin preparations currently clinically suitable for this symptom include solutions, ointments, gels, powders, liniments and sprays. These conventional preparations have poor skin adhesion and poor water resistance, and the drugs are easily wiped off or washed off after application, require repeated administration, and can contaminate clothing. Some preparations need to be bandaged during use, resulting in poor air permeability of the wound, prone to secondary ...

AI Technical Summary

Problems solved by technology

The film spraying agent usually has problems such as long film forming time, poor water resistance, insufficient film performance, and short maintenance time.

The main reasons for these problems are: the use of a single material cannot obtain ideal film-forming properties, and there is no suitable preparation method to integrate a variety of materials with different physical and chemical properties and effects into the same water system to synergistically play the role of materials

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