Atomoxetine tablet composition
A technology for atomoxetine tablets and compositions, applied in the field of pharmaceutical preparations, can solve the problems that highly bitter and highly water-soluble drugs are not very successful, affect normal use, loose tablets, etc., and achieve content uniformity that is difficult to control and improve. The effect of content uniformity and stability improvement
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Embodiment 1
[0022] Example 1. Atomoxetine 5g, β-cyclodextrin 18g, calcium sulfate 30g, fumed silica 16g, lactose 30g, low-substituted hydroxypropyl methylcellulose 6g, sorbitol 2g, magnesium stearate 0.8 g, prepare 1000 tablets according to the preparation method described in the technical scheme.
Embodiment 2
[0023] Example 2, atomoxetine 30g, β-cyclodextrin 26g, calcium sulfate 46g, fumed silica 8g, lactose 50g, low-substituted hydroxypropyl methylcellulose 12g, sorbitol 5g, magnesium stearate 1.5 g, prepare 1000 tablets according to the preparation method described in the technical scheme.
Embodiment 3
[0024] Example 3, atomoxetine 10g, β-cyclodextrin 22g, calcium sulfate 40g, fumed silica 12g, lactose 40g, low-substituted hydroxypropyl methylcellulose 9g, sorbitol 4g, magnesium stearate 1.0 g, prepare 1000 tablets according to the preparation method described in the technical scheme.
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