Mouse neurosurgery bed

A neurosurgery and operating bed technology, applied in the field of machinery, can solve problems such as operation failure, restlessness, and hearing loss in mice, and achieve the effects of avoiding serious complications, simple structure, and convenient use.

Pending Publication Date: 2018-05-29
王存金
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

Although the brain stereotaxic instrument can effectively fix the head of the mouse and has a three-dimensional coordinate system, it does not consider how to make the mouse more comfortable to cooperate with the operation from the perspective of comfort, and often the mouse is precisely because of this Uncomfortable special positions lead to restlessness and struggle during the operation, which eventually lead to the failure of the operation
In addition, the mouse's head is generally fixed by ear sticks, but this fixation method easily damages the mouse's tympanic membrane and causes hearing loss in the mouse. This result is disastrous for experiments on hearing
It has been found through research that once the mice struggle during the operation, it is almost impossible to perform the operation under relatively light anesthesia, so it is necessary to continuously add anesthetics, which will easily lead to excessive use of anesthetics and cause damage to the functions of the important organs of the mice. impact; the mice will die during the operation due to the severe distortion of the body position, which leads to the obstruction of the blood circulation in the large blood vessels and the head; the above two are caused by the mice being fixed in an uncomfortable position; The body is kept warm, which can easily induce hypothermia and lead to serious postoperative complications

Method used

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  • Mouse neurosurgery bed
  • Mouse neurosurgery bed
  • Mouse neurosurgery bed

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0024] Example 1 (see Figure 1 to Figure 3 ):

[0025] A neurosurgery bed for mice, comprising: a body solid table, an adjustment device and a head fixing device, the head fixing device is fixed on the front end of the body fixing table through the adjustment device, the body solid table fixes the body of the mouse, and the head is fixed The device immobilizes the head of the mouse. In addition, if the head fixing device is separated from the body solid platform, it will be difficult to make the mouse head and body on the same plane, and it is easy to distort the large blood vessels in the neck, resulting in insufficient blood supply to the brain.

[0026] The body fixing platform includes a fixed plate 1, a lifting device and a clamping and tightening device 3. The fixed plate 1 is fixed on the lifting device, and there are four clamping and tightening devices 3, and the four clamping and tightening devices 3 correspond to mouse The limbs of the mouse are arranged on the f...

Embodiment 2

[0029] Example 2 (see Figure 4 ):

[0030] A neurosurgery bed for mice, comprising: a body solid table, an adjustment device and a head fixing device, the head fixing device is fixed on the front end of the body fixing table through the adjustment device, the body solid table fixes the body of the mouse, and the head is fixed The device immobilizes the head of the mouse. In addition, if the head fixing device is separated from the body solid platform, it will be difficult to make the mouse head and body on the same plane, and it is easy to distort the large blood vessels in the neck, resulting in insufficient blood supply to the brain.

[0031] The body fixing platform includes a fixed plate 1, a lifting device and a clamping and tightening device 3. The fixed plate 1 is fixed on the lifting device, and there are four clamping and tightening devices 3, and the four clamping and tightening devices 3 correspond to mouse The limbs of the mouse are arranged on the fixed plate 1...

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Abstract

The invention discloses a mouse neurosurgery bed which comprises a body fixing platform, an adjusting device and a head fixing device. The heat fixing device is fixed at the front end of the body fixing platform through the adjusting device, the body fixing platform fixes the body of a mouse, and the head fixing device fixes the head of the mouse; the adjusting device comprises an upward-downwardmoving plate and a leftward-rightward moving plate, the leftward-rightward moving plate is arranged on the front end face of the body fixing platform in a manner of being capable of sliding leftwardsand rightwards, the upward-downward moving plate is arranged on the front end face of the leftward-rightward moving plate in a manner of being capable of sliding upwards and downwards, and two inserting holes are formed in the front end face of the upward-downward moving plate; the head fixing device comprises a fixing ring, a nose clamp and two bitamporal fixing rods, the nose clamp and the bitamporal fixing rods are arranged on the fixing ring, the fixing ring is provided with an opening, and inserting pins are symmetrically fixed at two open ends of the fixing ring and correspondingly inserted in the two inserting holes. Through the above mode, the mouse neurosurgery bed can fix body position of the mouse comfortably, so that the mouse can well cooperate with neurosurgery operation to complete surgery smoothly.

Description

technical field [0001] The invention relates to the technical field of machinery, in particular to a mouse neurosurgery operating bed. Background technique [0002] With the continuous deepening of basic neuroscience research, mouse neurosurgery such as mouse craniotomy or drilling stereotaxic injection has become a basic experimental skill that workers engaged in basic neuroscience research need to master. Because most of these operations are microscopic and delicate operations, the head of the mouse needs to be absolutely immobilized during the operation. However, due to the small size of the mouse skull, it is difficult to fix the head. [0003] At present, when performing neurosurgery on mice, the brain stereotaxic instrument is mainly used to fix the head of the mouse. During the whole operation, the head of the mouse is tightly fixed, and the body lies on the table without heat preservation device. , the head keeps tilting back. Although the brain stereotaxic instrum...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61D3/00
CPCA61D3/00A61D2003/006A61D2003/003
Inventor 王存金潘昱辰
Owner 王存金
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