Biological sample imaging spectrometer applicable to water window x rays

Abstract

The invention discloses a biological sample imaging spectrometer applicable to water window x rays. The imaging spectrometer comprises a laser, a wedge prism, a target device, a multi-layer mirror, anoptical filter, a pinhole, a sample and a Schwarzschild projection objective or a Fresnel zone plate, wherein the target device comprises target materials prepared from two different materials; a light source of the laser is split into two beams after passing through the wedge prism, the beams are focused and irradiate one target material in the target device, two plasmas are generated, the laseris driven to act to generate collisional plasmas, and radiated x ray source light is collected and reflected by the multi-layer mirror; the to-be-imaged sample is irradiated by the reflected light source through the optical filter and the pinhole, and the light source passes through the Schwarzschild projection objective or the Fresnel zone plate and is recorded by a CCD. The biological sample imaging spectrometer is low in cost and convenient to apply, the light source is more effective, and even an element with large atomic number can be used as the target material.

Description

technical field [0001] The invention belongs to the technical field of biological sample imaging, in particular to a biological sample imaging spectrometer suitable for "water window" X-rays. Background technique [0002] X-rays in the 2.3-4.4 nanometer band are called "water window". Since the absorption rate of protein is more than 10 times that of water, this radiation is very suitable as a light source for imaging biological samples and underwater military communications. Early researchers have succeeded in studying the imaging of biological samples based on the synchrotron radiation light source as a "water window" light source. The "water window" biological sample imaging technology has a large number of potential applications, such as being able to study the mechanism of diseases, such as Berkeley Laboratory in the United States has done early research and was reported by Nautre and other journals (Nature 435 (2005) 1210-1213). [0003] However, the high cost of main...

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Problems solved by technology

As a "water window" light source, the team has obtained some biological sample imaging, but the existing problem is low efficiency; (2) the current problem of gas target technology represented by teams such as Giessen University in Germany is also low efficiency; It should be noted that the optical imaging systems of these two schemes are based on Fresnel zone-plate optical technology

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