A kind of extract for treating pelvic inflammatory disease and preparation method thereof

An extraction method and extract technology, applied in the field of pharmaceutical invention, can solve the problems of affecting the curative effect, infection, low effective content, etc., and achieve the effects of alleviating inflammatory response and pathological changes, reducing the level of IL-6, and reducing the level of MDA.

Active Publication Date: 2021-02-02
ANHUI JINGFANG PHARMA
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0006] 2. Infection after intrauterine surgery
[0007] Such as placement or removal of intrauterine contraceptive ring, curettage, tubal fluid, hysterosalpingography, hysteroscopy, submucosal myomectomy, etc., due to preoperative sex life or surgical disinfection is not strict or preoperative Improper selection of indications can lead to the onset and spread of acute infection after surgery; some patients do not pay attention to personal hygiene after surgery, or do not follow the doctor's advice after surgery, which can also cause bacterial infection and cause pelvic inflammatory disease
[0008] 3. Poor menstrual hygiene
[0016] However, this product and other similar products on the market have the disadvantages that the active ingredients cannot be fully extracted and utilized, the effective content is low, there are many impurities, the dosage is large, and the curative effect is affected. , taking small doses of Chinese patent medicine preparations has attracted more and more attention, and has broad market prospects

Method used

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  • A kind of extract for treating pelvic inflammatory disease and preparation method thereof
  • A kind of extract for treating pelvic inflammatory disease and preparation method thereof
  • A kind of extract for treating pelvic inflammatory disease and preparation method thereof

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0068] Embodiment 1: Granules

[0069] 1. Drug composition: Diren 800g, Liangmianzhen 240g, Angelica 200g, Wuzhi Maotao 160g, Chuanposhi 200g.

[0070] 2. Preparation method:

[0071] 1) Weigh the clean Chinese medicinal material, add 10 times the amount of water, heat to 90°C to extract 3 times, each time for 2 hours, filter, the filtrate is concentrated to a relative density of 1.25 at a temperature of 60°C, cool, and add 50% ethanol , stand still for 24 hours, filter, recover ethanol from the filtrate, concentrate to a thick paste, dry, grind into fine powder, and set aside.

[0072] 2) Take the medicinal material of Liangmianzhen, add 10 times the amount of water, heat to 90°C to extract 3 times, each time for 2 hours, filter, the filtrate is concentrated to a relative density of 1.20 at a temperature of 65°C, cool, add 55% ethanol, and let stand After 24 hours, filter, recover ethanol from the filtrate, concentrate to a thick paste, dry, grind into fine powder, and set ...

Embodiment 2

[0086] Embodiment 2: capsules

[0087] 1. Drug composition: Diren 750g, Liangmianzhen 250g, Angelica 100g, Wuzhi Maotao 80g, Chuanposhi 100g.

[0088] 2. Preparation method:

[0089] 1) Weigh the clean Chinese medicinal material, add 10 times the amount of water, heat to 90°C to extract 3 times, each time for 2 hours, filter, the filtrate is concentrated to a relative density of 1.25 at a temperature of 60°C, cool, and add 50% ethanol , stand still for 24 hours, filter, recover ethanol from the filtrate, concentrate to a thick paste, dry, grind into fine powder, and set aside.

[0090] 2) Take the medicinal material of Liangmianzhen, add 10 times the amount of water, heat to 90°C to extract 3 times, each time for 2 hours, filter, the filtrate is concentrated to a relative density of 1.20 at a temperature of 65°C, cool, add 55% ethanol, and let stand After 24 hours, filter, recover ethanol from the filtrate, concentrate to a thick paste, dry, grind into fine powder, and set a...

Embodiment 3

[0100] Embodiment 3: tablet

[0101] 1. Drug composition: Diren 1000g, Liangmianzhen 300g, Angelica 260g, Wuzhi Maotao 200g, Chuanposhi 260g.

[0102] 2. Preparation method:

[0103] 1) Weigh the clean Chinese medicinal material, add 10 times the amount of water, heat to 90°C to extract 3 times, each time for 2 hours, filter, the filtrate is concentrated to a relative density of 1.25 at a temperature of 60°C, cool, and add 50% ethanol , stand still for 24 hours, filter, recover ethanol from the filtrate, concentrate to a thick paste, dry, grind into fine powder, and set aside.

[0104] 2) Take the medicinal material of Liangmianzhen, add 10 times the amount of water, heat to 90°C to extract 3 times, each time for 2 hours, filter, the filtrate is concentrated to a relative density of 1.20 at a temperature of 65°C, cool, add 55% ethanol, and let stand After 24 hours, filter, recover ethanol from the filtrate, concentrate to a thick paste, dry, grind into fine powder, and set a...

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PUM

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Abstract

The invention relates to an extract for treating pelvic inflammatory disease and its preparation method and application. The extract is made of the following Chinese medicinal materials in parts by weight: Diren 600-1000 parts, Liangmianzhen 180-300 parts, Angelica sinensis 150-260 parts 120-200 parts of Wuzhi Maotao, 150-230 parts of Chuanposhi. Its active ingredients are: diren alcohol water extract, liangmianzhen alcohol water extract, angelica alcohol water extract, five-finger peach alcohol water extract, piercing stone alcohol water extract, prepared by water extraction, alcohol extraction and other methods The extract has high content of active ingredients, small dosage, no toxic and side effects, and has definite curative effect in the treatment of acute and chronic pelvic inflammatory disease and other common gynecological diseases.

Description

Technical field: [0001] The invention relates to the field of medical inventions, in particular to an extract for treating pelvic inflammatory disease and a preparation method thereof. Background technique [0002] Pelvic inflammatory disease refers to inflammation of the female reproductive organs, connective tissue around the uterus and pelvic peritoneum. The clinical manifestations are acute pelvic inflammatory disease and chronic pelvic inflammatory disease. Chronic pelvic inflammatory disease is often caused by incomplete treatment in the acute phase, and its onset time is long and the condition is more stubborn. Bacteria retrograde infection, through the uterus, fallopian tubes and reach the pelvic cavity. But in real life, not all women will suffer from pelvic inflammatory disease, and the incidence is only a minority. This is because the female reproductive system has a natural defense function. Under normal circumstances, it can resist the invasion of bacteria. O...

Claims

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Application Information

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Patent Type & Authority Patents(China)
IPC IPC(8): A61K36/758A61P15/00
CPCA61K36/185A61K36/232A61K36/60A61K36/758A61K2236/331A61K2236/333A61K2236/39A61K2236/53A61P15/00A61K2300/00
Inventor 高武左言东王宗保王琳聂飞龙熊寅攀陈月红吕迎四陈守清肖传凤胡文高王元生
Owner ANHUI JINGFANG PHARMA
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