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Coenzyme q10 preparation for auxiliary treatment of male oligoasthenospermia and preparation method thereof

A technology for adjuvant treatment of asthenospermia, which is applied in the field of health care products and pharmaceuticals, and can solve the problems that the amount of oral administration and absorption of consumers is not proportional, the spermatogenic function of the reproductive system cannot be enhanced, and the absorption rate and utilization rate are low. Antioxidant effect, bioavailability improvement, effect of simple steps

Active Publication Date: 2021-05-04
SHANGHAI JINCHENG PHARMACEUTICAL CO LTD
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  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0004] At present, among the people who take coenzyme Q10, a certain proportion of them are for the purpose of tonifying the kidney and replenishing essence, but because coenzyme Q10 can only remove active oxygen in the reproductive system, but cannot enhance the spermatogenic function of the reproductive system, the curative effect is not significant ;In addition, the existing products of coenzyme Q10 mostly use a variety of pharmaceutical ingredients and chemical additives for production, and the interaction of various chemical additives affects the absorption of the human body, resulting in a disproportionate amount of oral intake and absorption by consumers, and the absorption of coenzyme Q10 products in the human body Both rate and utilization are low

Method used

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  • Coenzyme q10 preparation for auxiliary treatment of male oligoasthenospermia and preparation method thereof
  • Coenzyme q10 preparation for auxiliary treatment of male oligoasthenospermia and preparation method thereof
  • Coenzyme q10 preparation for auxiliary treatment of male oligoasthenospermia and preparation method thereof

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Effect test

Embodiment approach

[0032]According to a preferred embodiment of the present invention, the oil is an oil having a higher body absorption, preferably from coconut oil, rice bran, soybean oil, corn oil, peanut oil, olive oil, sesame oil or flaxseed oil. Place or multiple.

[0033]In the present invention, since the coenzyme Q10 is insoluble in water, it is necessary to dissolve it in the fat to promote the dissolution dispersion of the coenzyme Q10.

[0034]In a further preferred embodiment, the grease is selected from one or more of coconut oil, rice bran oil, soybean oil, corn oil or flaxseed oil.

[0035]In a further preferred embodiment, the grease is selected from one or more of coconut oil, rice bran oil or flaxseed oil.

[0036]The present inventors have been studied that natural functional grease coconut oil can quickly digest in the body, not easy to deposit as fat in the tissue, and have anti-viruses and antibacterial, promoting metabolism, etc., which have a high nutritional value. There are 80% of unsat...

Embodiment 1

[0130](1) The raw materials of the coenzyme Q10 preparation in this example include the following weight ratio components:

[0131]

[0132]

[0133](2) preparation method

[0134](1) We will weigh 3KG, 3KG Hawthorn, 4kg Barley Day, 2kg Macon and 5kg Huangqi, mixed, mixed, add 80-liter water soaking for 30 minutes, then boil, filter, medicine spare; medicine residue, add 60 liters Decoction, filtration, and mixture; repeat the above operation; combined with 3 decoction liquids together, then simply cook, so that the liquid concentrate to 20% water content to obtain a thick extract; 10% mannitol was added to the thickened paste as a protective agent, pre-freezing 10 h in the lyophilizer (Alpha1-4, Germany Christ), and then under -40 ° C low temperature vacuum sublimation dry 14h, and finally Vacuum was evolved for 10 h at 30 ° C, prepared to obtain a dry extract (a water content of 4%), and the pulverization of 100 mesh sieves was obtained to obtain a dry powder of the active Chinese medicine co...

Embodiment 2

[0144]The method used in this example is similar to that of Example 1, and the difference is only that the grease of the oil and rice bran oil, the amount of the coconut oil and rice bran oil is 200 g and 100 g, respectively.

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Abstract

The invention discloses a coenzyme Q10 preparation for the auxiliary treatment of male oligoasthenozoospermia and its preparation method and application, wherein the raw materials of the coenzyme Q10 preparation mainly include coenzyme Q10, sugar, oil, antioxidant and emulsifier. Natural antioxidants are used as raw materials to prepare coenzyme Q10 preparations, which reduce the adverse effects of chemical additives on the human body and increase the bioavailability of coenzyme Q10; and add active Chinese medicine components with the functions of nourishing kidney and essence, nourishing qi and promoting blood circulation to coenzyme Q10 preparations, Synergistic with coenzyme Q10, it effectively improves the efficacy of treating male oligoasthenospermia. The coenzyme Q10 preparation provided by the invention has balanced component compatibility, simple and easy-to-obtain raw materials, stable finished product quality and high bioavailability.

Description

Technical field[0001]The invention belongs to the technical field of medicines and health care products, and more particularly to a coenzyme Q10 preparation with auxiliary treatment of less spermia and its preparation method thereof.Background technique[0002]Coenzyme Q is a fat-soluble quinone-based compound existing in nature, which is similar to vitamin K, vitamin E and tattooxis, and is an important component of mitochondrial in animal and plant cells. As a cellular breathing chain Hydrogen, causes the cells to produce a natural antioxidant and cell metabolic activator. Various organisms contain a unique coenzyme q, and the coenzyme Q10 is present in the human body.[0003]Coenzyme Q10 (CoQ10), also known as "ubiquinone", yellow or orange crystal powder, pouring light, thermally sensitive, soluble in ethanol and oil phase solvent, in each cell in the human body, The function of promoting energy supply is an essential substance. The coenzyme Q10 helps generate energy by stimulating ...

Claims

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Application Information

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Patent Type & Authority Patents(China)
IPC IPC(8): A61K31/122A61K47/00A61K36/8968A61P15/08
CPCA61K31/122A61K36/39A61K36/40A61K36/43A61K36/481A61K36/746A61K36/8968A61P15/08A61K2300/00
Inventor 傅苗青周白水巩绪彦邱林
Owner SHANGHAI JINCHENG PHARMACEUTICAL CO LTD
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