Proton transfer reaction mass spectrometer and detection method thereof

Abstract

The invention provides a proton transfer reaction mass spectrometer and a detection method thereof. An ion source is used to ionize initial reactant gas which accesses the ion source to initial reactant ions. The initial reactant ions collide with molecules of a to-be-tested sample in a drift tube and a proton transfer reaction occurs to generate to-be-tested sample ions. A rectangular ion trap isused to capture the to-be-tested sample ions which enter the rectangular ion trap, and make the captured to-be-tested sample ions resonate and be expelled according to mass-to-charge ratio. An ion detector is used to detect the to-be-tested sample ions which are expelled by the rectangular ion trap, to obtain a mass spectrum of the to-be-tested sample ions. Since an electrode on the front end ofthe rectangular ion trap can be used together with an electrode on the tail end of the drift tube. The rectangular ion trap can be directly connected with the drift tube, so that an intermediate ion transfer step is not needed, ion loss in a transmission process is reduced, instrument sensitivity is improved, and structure of the mass spectrometer is greatly simplified.

Description

technical field [0001] The invention relates to the technical field of mass spectrometers, in particular to a proton transfer reaction mass spectrometer and a detection method thereof. Background technique [0002] PTR-MS (Proton Transfer Reaction–Mass Spectrometry, proton transfer reaction mass spectrometry) has been widely used in life sciences, Important fields such as homeland security, food safety and atmospheric trace monitoring. [0003] Existing proton transfer reaction mass spectrometers generally ionize the initial reaction gas (such as water vapor) into initial reaction ions (such as H 3 o + ), and then let the initial reaction ions enter the drift tube, and collide with the sample molecules (such as VOCs) in the drift tube to undergo a proton transfer reaction to generate the sample ions to be tested, and then perform mass analysis on the sample ions to be tested by the mass analyzer. The instrument detects the ions of the sample to be tested to obtain a mass ...

AI Technical Summary

Problems solved by technology

[0004] Although mass analyzers such as quadrupole mass analyzers and time-of-flight mass analyzers used in existing proton transfer reaction mass spectrometers all have good mass analysis capabilities, but since the drift tube cannot be directly connected to the above-mentioned mass analyzers, That is to say, after the sample ions to be measured come out of the drift tube, they need to pass through the transmission of the intermediate link before they can enter the mass analyzer. Therefore, the structure of the mass spectrometer is more complicated.

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