External pharmaceutical preparation for preventing and treating rheumatoid arthritis
A pharmaceutical preparation and rheumatoid technology, applied in the field of medicine, can solve the problems of limited dosage, increased frequency of administration, unfavorable drug effect, etc., and achieve the effect of enhanced synergistic effect
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[0018] Example 1
[0019] Take commercially available medicinal NAB, Ligusticum chuanxiong oil, azone, medicinal excipients hydroxypropyl methylcellulose, ethanol, propylene glycol, ethyl p-hydroxybenzoate and purified water, etc., and prepare according to the existing preparation method of gel A gel containing 1.0% (mass, the same below) NAB, 1.0% (mass) Ligusticum chuanxiong oil and 1.0% (mass) azone (mass ratio of azone and Ligusticum chuanxiong oil 1:1), namely sample 1. In the gel, hydroxypropyl methylcellulose is used as an excipient, and its content is 1.0%.
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[0020] Example 2
[0021] Take commercially available medicinal NAB, Ligusticum chuanxiong oil, azone, medicinal excipients hydroxypropyl methylcellulose, ethanol, propylene glycol, ethyl p-hydroxybenzoate and purified water, etc., and prepare according to the existing preparation method of gel A gel containing 0.7% NAB, 3.0% Ligusticum chuanxiong oil and 1.0% Azone (mass ratio of azone and Ligusticum chuanxiong oil 1:3), namely sample 2. The content of hydroxypropyl methylcellulose in the gel is 1.0%.
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[0022] Example 3
[0023] Take commercially available medicinal NAB, Ligusticum chuanxiong oil, azone, medicinal excipients hydroxypropyl methylcellulose, ethanol, propylene glycol, ethyl p-hydroxybenzoate and purified water, etc., and prepare according to the existing preparation method of gel A gel containing 0.5% NAB, 1.0% Ligusticum chuanxiong oil and 2.0% Azone (mass ratio of azone and Ligusticum chuanxiong oil 2:1), namely sample 3. The content of hydroxypropyl methylcellulose in the gel is 1.0%.
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