Application of balsampear stem extract compound in preparation of blood sugar reducing drugs or foods

Abstract

The invention provides an application of a balsampear stem extract compound in the preparation of blood sugar reducing drugs or foods. Experiments show that the intake of glucose by FL83B cells is significantly enhanced in the presence of the compound, so the compound is comparable to insulin and puerarin in effect; the compound can effectively alleviate the resistance of cells to insulin and promote the glucose intake, and the improvement effect of the compound is better than that of the puerarin; and additionally, a result of investigation of the influences of the compound on the proliferation of the FL83B cells shows that the compound does not inhibit the proliferation of the FL83B cells when the concentration does not exceed 2.5 [mu]g / mL, and has a certain promotion effect on the proliferation of the FL83B cells when the concentration is in the range of 0.625-2.5 [mu]g / mL and the contact time is 24-72 h. The use of the compound in the preparation of the blood sugar reducing drugs or foods is used based on the above beneficial finding, so the optional range of the blood sugar reducing drugs is enlarged, and the medicinal use of the balsampear stem extract compound is expanded.

Description

technical field [0001] The invention relates to the technical field of chemical medicines, and further relates to new medical applications of substances, in particular to the application of a bitter melon vine extract compound for preparing hypoglycemic drugs or food. Background technique [0002] Diabetes mellitus is one of the most common endocrine and metabolic disorders, and the prevalence of adult diabetes has been increasing over the past few decades. Therefore, it is urgent to further explore the pathogenesis of diabetes, treat and prevent the progression of diabetes. There are three main forms of diabetes namely type I, type II and gestational diabetes. Among them, type 2 diabetes accounts for more than 90% of the total number of diabetes. Insulin resistance and pancreatic β-cell dysfunction are the two main links leading to the occurrence of type Ⅱ diabetes. In recent years, people have begun to use insulin-resistant cell models to screen anti-diabetic drugs, stu...

AI Technical Summary

Problems solved by technology

[0005] The present invention aims at the technical defects of the prior art, and provides an application of a bitter gourd vine extract compound for the preparation of hypoglycemic drugs or food, so as to solve the problem of active ingredients used in the preparation of hypoglycemic drugs or hypoglycemic foods in the prior art, Technical issues with limited range of options

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