Effervescent tablet for improving dyslipidemia and use thereof

A technology for dyslipidemia and effervescent tablets, which can be applied to medical preparations containing active ingredients, pharmaceutical formulas, metabolic diseases, etc., and can solve problems such as unreported research on blood lipid-lowering activity
CN108553489BActive Publication Date: 2021-04-27QINGHAI UNIVERSITY
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Patent Information

Authority / Receiving Office
CN Β· China
Patent Type
Patents(China)
Current Assignee / Owner
QINGHAI UNIVERSITY
Publication Date
2021-04-27

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Abstract

The invention provides an effervescent tablet for improving dyslipidemia, which is prepared from raw and auxiliary materials in the following weight ratio: 5-55 parts of Nitraria japonica seed extract, 2-4 parts of citric acid, 3-5 parts of fumaric acid 5 parts, 10-20 parts of fructooligosaccharide, 10-25 parts of sorbitol, 2-10 parts of sodium bicarbonate. The invention also provides the preparation method and application of the effervescent tablet. The research of the present invention shows that the Nitraria japonica seed extract provided by the present invention can reduce total cholesterol, total triglyceride, and low-density lipoprotein cholesterol in the blood serum of hyperlipidemic rats, improve its high-density lipoprotein cholesterol, and can reduce to a certain extent against abnormal weight gain in rats with hyperlipidemia. At the same time, the pathological section observation of the liver tissue of each group of rats also found that the extract can improve the changes of adipose tissue and cell morphology of fatty liver to varying degrees, which provides a good foundation for the clinical prevention or treatment of hyperlipidemia or fatty liver. new options.
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Description

technical field

[0001] The invention specifically relates to an effervescent tablet for improving dyslipidemia, which uses the extract of the water part of Nitraria thorn seed as a raw material, and its application.

[0002] technical background

[0003] Hyperlipidemia is the main cause of atherosclerosis and related diseases such as coronary heart disease, ischemic brain disease and peripheral vascular disease. Although the incidence of diseases related to atherosclerosis has been improved due to drug treatment and prevention, the above conditions still account for a large proportion of morbidity and mortality in middle-aged and elderly people. Due to the increasing prevalence of obesity and the aging of the world population, the annual incidence and number will increase substantially in the next decade. Dyslipidemia is caused by abnormal blood lipid metabolism, such as the increase of total cholesterol (TC), triglyceride (TG), low-density lipoprotein (LDL-C) and the decrea...

Claims

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