Cell co-culture unit

Abstract

The invention provides a cell co-culture unit and belongs to the technical field of cell culture. The cell co-culture unit comprises at least two culture dishes stacked up and down, wherein two optional adjacent culture dishes comprise an upper culture dish and a lower culture dish; an inner circulation channel or an inner seepage channel communicated with inner cavities of the two culture dishesis formed between the upper culture dish and the lower culture dish; an upper overlapping structure overlapped on the lower culture dish is formed in the upper culture dish, and the lower part of theupper culture dish is inserted into the lower culture dish; an upper breathable structure used for enabling the inner cavity of the lower culture dish in the two adjacent culture dishes to communicatewith outside is formed in the upper overlapping structure. Different cells are cultured on each culture dish to simulate a growth environment of cells in a normal organism; moreover, with the adoption of a mutually overlapped stacking manner, the cell co-culture unit is conveniently constructed, and the problem in the prior art that the cell co-culture unit is inconvenient to operate is solved.

Description

technical field [0001] The present invention relates to a cell co-culture unit. Background technique [0002] At present, traditional single-layer cell culture is used in in vitro toxicology and pharmacology experiments. This culture method cannot truly simulate the in vivo microenvironment in which cells live, and may cause certain deviations when studying the influence of exogenous substances on the matrix. In order to better establish a culture system similar to the in vivo environment, in the late 1980s, researchers developed a cell co-culture technology based on the original two-dimensional monolayer cell culture. [0003] Cell co-culture technology is a technology in which two or more types of cells are co-cultured in a unified environment. Compared with single-cell monolayer culture, it has the advantage of better responding to the in vivo environment. At present, the existing co-culture methods include direct contact co-cultivation and indirect contact co-cultivatio...

AI Technical Summary

Problems solved by technology

[0005] The purpose of the present invention is to provide a cell co-culture unit to solve the problem of inconvenient operation of the cell co-culture unit in the prior art

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