Method for repairing rabbit achilles tendon injury through continuous stretching stress stimulation

A stress and stretch technology, applied in the repair field, can solve problems such as changing from loose plaster fixation to functional plaster

Inactive Publication Date: 2018-10-09
王继宏
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Problems solved by technology

[0003] The purpose of the present invention is to provide a method for continuous stretch stress stimulation to repair rabbit Achilles tendon injury

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  • Method for repairing rabbit achilles tendon injury through continuous stretching stress stimulation

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Embodiment Construction

[0008] In order to make the purpose, technical solution and advantages of the present invention more clear, the embodiments of the present invention will be described in detail below in conjunction with the accompanying drawings.

[0009] Tendon injury is a common injury in clinical practice. Tendon adhesion or joint stiffness often occurs after repair, leading to severe dysfunction. At present, domestic and foreign scholars' research on tendon repair mainly focuses on the improvement of intraoperative suture method and the repair and replacement of tendon sheath, but the postoperative functional recovery has not achieved satisfactory results. In addition, tendon rupture is most common in young and middle-aged people, and it has a greater impact on family and society, so attention should be paid.

[0010] We have found in long-term clinical practice that although plaster fixation at the loose tendon position after tendon repair can minimize the chance of tendon re-rupture, it ...

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Abstract

The invention relates to a method for repairing the rabbit achilles tendon injury through continuous stretching stress stimulation. The method comprises the steps that a male New Zealand white rabbitis adopted, and through hind limb achilles tendon dividing operation, a rabbit achilles tendon acute breakage animal model is established; at functional positions, ankle joints of the rabbit are fixedthrough gypsum to limit moving of the ankle joints of the rabbit, continuous stress stimulation is given to the achilles tendon breakage section, and the animal model for achilles tendon repairing under early-stage continuous stress stimulation is constructed; through general observation and microscopic observation, the early-stage histological change after rabbit achilles tendon acute breakage repairing operation under fixing of the functional positions of the ankle joints is defined; through the ELISA method, protein expression situations of I-type collagen, TGF-beta1, bFGF, VEGF, PDGF andIGF-1 in repair tissues are detected; and by detecting the maximum strength, the maximum load and the rigidity index, the biomechanical characteristics of the repair tissues after early-stage continuous stress stimulation is given in the rabbit achilles tendon acute breakage postoperation repairing process are evaluated.

Description

technical field [0001] The invention relates to repair technology, in particular to a method for repairing rabbit Achilles tendon injury by continuous stretch stress stimulation. Background technique [0002] Tendon injury is a common type of injury, and tendon adhesions or joint stiffness often occur after repair, resulting in severe dysfunction. At present, domestic and foreign scholars' research on tendon repair mainly focuses on the improvement of intraoperative suture method and the repair and replacement of tendon sheath, but various treatment methods have not yet achieved satisfactory functional recovery. In long-term clinical practice, it has been found that plaster fixation at the loose tendon position after tendon repair can minimize the chance of tendon re-rupture, but it will also cause tendon contracture or joint stiffness, which greatly increases the difficulty and difficulty of later functional exercises. Rehabilitation time can even cause permanent dysfuncti...

Claims

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Application Information

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IPC IPC(8): A61B5/00
CPCA61B5/4848
Inventor 王继宏温树正蔺晓慧王玉仲王永飞殷超王小龙姜东崔立舜冯鹏飞
Owner 王继宏
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