Ultrasonic, photoacoustic and fluorescent three-mode imaging system

An imaging system, a three-modal technology, applied in fluorescence/phosphorescence, material analysis by optical means, measurement devices, etc., can solve the problems of limited detection angle, low resolution, and long scanning time of photoacoustic computed tomography, etc. Achieve the effect of improving imaging resolution, improving imaging speed, and reducing the amount of data collection

Inactive Publication Date: 2018-10-30
HARBIN INST OF TECH AT WEIHAI
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  • Abstract
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  • Application Information

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Problems solved by technology

However, photoacoustic computed tomography has disadvantages such as long scanning time, low resolution and limited detection angle.

Method used

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  • Ultrasonic, photoacoustic and fluorescent three-mode imaging system
  • Ultrasonic, photoacoustic and fluorescent three-mode imaging system
  • Ultrasonic, photoacoustic and fluorescent three-mode imaging system

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Embodiment Construction

[0037] In order to make the purpose, technical solutions and advantages of the embodiments of the present invention clearer, the technical solutions in the embodiments of the present invention will be clearly and completely described below in conjunction with the drawings in the embodiments of the present invention. Obviously, the described embodiments It is a part of embodiments of the present invention, but not all embodiments. Based on the embodiments of the present invention, all other embodiments obtained by persons of ordinary skill in the art without making creative efforts belong to the protection scope of the present invention.

[0038] An embodiment of the present invention provides a three-modal imaging system of ultrasound, photoacoustic and fluorescence, see Figure 1-Figure 2 , including:

[0039] Control processing module 100, data acquisition module 200, motion scanning module 300 and laser light source module 400;

[0040] The motion scanning module 300 is p...

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Abstract

The invention provides an ultrasonic, photoacoustic and fluorescent three-mode imaging system. The ultrasonic, photoacoustic and fluorescent three-mode imaging system comprises a laser light source module, a motion scanning module, a data acquisition module and a control processing module; the laser light source module is used for providing pulsed laser radiation to an imaging sample and enablingthe imaging sample to generate photoacoustic and fluorescent signals and sending synchronous trigger signals to the data acquisition module and the control processing module; the motion scanning module is used for performing three-dimensional scanning on the sample according to preset motion parameters; the data acquisition module is used for acquiring the photoacoustic/ultrasonic/fluorescent signals generated from the sample; the control processing module is used for receiving trigger pulse signals of a pulsed laser light source, enabling a motion scanning device to scan a target sample according to control instruments, processing received data of the target sample and fusing photoacoustic/ultrasonic/fluorescent images to acquire multimodal reconstructed images. By the arrangement, scanning time in imaging is reduced, and imaging resolution and imaging speed of the imaging system are increased.

Description

technical field [0001] The invention relates to the technical field of photoacoustic imaging, in particular to an ultrasound, photoacoustic and fluorescence three-mode imaging system. Background technique [0002] Photoacoustic Imaging (PAI) is a new type of non-destructive biomedical imaging method based on the difference in optical absorption characteristics inside biological tissues and using ultrasound as the information carrier. It has the high contrast characteristics of pure optical imaging and pure The deep penetrating nature of ultrasound imaging. Photoacoustic imaging detects the photoacoustic signal generated by the light absorber in biological tissue due to the instantaneous thermoelastic effect, replaces photon detection with sound waves, avoids the influence of optical scattering in principle, and breaks through the "soft limit" of optical imaging depth , about 1mm, can realize deep tissue living imaging with a depth of 7cm. Photoacoustic imaging not only has...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): G01N21/17G01N21/64
CPCG01N21/1702G01N21/6402
Inventor 孙明健胡德鹏屈亚威马立勇刘旸马一鸣冷官冀李超
Owner HARBIN INST OF TECH AT WEIHAI
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