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Weightlessness response training method for mice

A technology of weightless response and training method, applied in the field of animal training, can solve the problems of unsatisfactory results and achieve high accuracy.

Active Publication Date: 2018-11-02
JIANGNAN UNIV
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

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Problems solved by technology

[0004] In the existing scientific research field, many experiments need to be carried out under the condition of weightlessness, but for mice, their respective characteristics are different, and their responses to the situation of weightlessness are also different. Under such circumstances, the results obtained in the research Unsatisfactory, on this basis, the applicant has developed a training method for the weightlessness response of mice to further solve this problem

Method used

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  • Weightlessness response training method for mice
  • Weightlessness response training method for mice
  • Weightlessness response training method for mice

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Experimental program
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Embodiment

[0030] A kind of training method of mouse weightlessness reaction is related in the present embodiment, comprises the following steps:

[0031] (1) Prepare experimental equipment: see Figure 1-2 , the experimental equipment includes a weightlessness simulation device, a cage 4, a fixed seat 2, a loudspeaker and a mouse heart rate measuring instrument. The weightlessness simulation device includes a vertically arranged support guide rail 1 and a linear motor 3 located on the support guide rail 1. The fixing base 2 is arranged on the side of the cage 4 and is slidably matched with the support guide rail 1. The cage 4 passes through the fixing base 2 and the support guide rail. The cooperation of 1 can simulate the state of weightlessness. There are two fixed seats 2, which are respectively located in the middle of the two sides of the cage 4. A control device is also provided on the cage 4. The control device is used to control the movement of the fixed seat 2 up and down alon...

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Abstract

The invention discloses a weightlessness response training method for mice. The weightlessness response training method includes steps of (1), selecting a plurality of healthy mice with identical weekages and consistent gender and raising each mouse in a cage; (2), screening the mice by means of carrying out weightlessness training on the mice by at least once, to be more specific, allowing the cages on weightlessness simulation devices to descend, formulating response rating scales according to the stress response ability of the mice, sequentially dividing the mice into first levels, secondlevels and third levels and selecting the mice at the second levels to be subjected to a next step; (3), carrying out weightlessness training on the mice at the second levels again, and repeatedly training the mice in the same way by 30-40 times; (4), determining training results, and to be more specific, measuring heart rate data of the trained mice and standby mice under identical test conditions to obtain comparison results. The weightlessness response training method has the advantages that weightless environments can be simulated by the aid of the weightlessness response training method,the mice can be trained, accordingly, the adaptability of the mice to the weightless environments can be verified, and the mice can be used for follow-up scientific experiments.

Description

technical field [0001] The invention relates to the field of animal training, in particular to a training method for weightlessness response of mice. Background technique [0002] Numerous studies have shown that weightlessness or simulated weightlessness can cause some systemic functions of humans or animals to be disordered, so it is very important to establish a device that simulates the environment of weightlessness. And mice are convenient to feed and manage, easy to control, and grow and reproduce quickly, so they are the most widely used in various experimental studies. [0003] The Chinese patent with the application number 200910082711.7 discloses a tail-suspension fixing device for rats, which can perform vibration / exercise training on tail-suspended rats under simulated weightlessness conditions; Rat simulated weightlessness treadmill exercise method and rat simulated weightlessness treadmill. But these existing technologies all only relate to the mouse weightle...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A01K15/02
CPCA01K15/02
Inventor 李秀卢镜宇商可心黎宁
Owner JIANGNAN UNIV