A set of SNP molecular markers for screening and/or detecting the abnormality rate of spermatozoa in breeding bulls

A technology for sperm deformity and bulls, applied in the field of molecular genetic biology, can solve problems such as functional verification that has not been reported, and achieve the effects of increasing farm economic benefits, high accuracy and reducing costs
CN108823322BActive Publication Date: 2021-08-03DAIRY CATTLE RES CENT SHANDONG ACADEMY OF AGRI SCI +1
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Patent Information

Authority / Receiving Office
CN · China
Patent Type
Patents(China)
Current Assignee / Owner
DAIRY CATTLE RES CENT SHANDONG ACADEMY OF AGRI SCI
Publication Date
2021-08-03

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Abstract

The invention belongs to the technical field of molecular genetics, and in particular relates to a group of SNP molecular markers used for screening and / or detecting the abnormality rate of sperm of breeding bulls. The PRKCB gene has 12 fully linked SNP sites, and 2 haplotypes were obtained by haplotype analysis, namely H1 (TCTGTTTCTAAC) and H2 (CTCACCCTCTCA), and there are a total of 3 haplotype combinations H1H1, H1H2, and H2H2. The correlation analysis with semen quality of bulls showed that the deformity rate of bulls with H1H2 haplotype combination was significantly lower than that of bulls with H1H1 and H2H2 haplotype combination after thawing frozen semen (P<0.05).
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Description

technical field

[0001] The invention belongs to the technical field of molecular genetics, and in particular relates to a group of SNP molecular markers used for screening and / or detecting the abnormality rate of sperm of breeding bulls. Background technique

[0002] The selection of excellent breeding bulls plays a decisive role in the genetic improvement and reproduction of dairy cows, and is of great significance to the sustainable and healthy development of the modern dairy industry. According to statistics, breeding bulls contribute more than 75% to the genetic progress of dairy cow populations. The quality of semen is directly related to whether the cow is pregnant or not. At present, in the developed countries of the dairy industry, an excellent breeding bull can produce 80,000 to 100,000 doses of frozen semen per year, up to 250,000 doses, which is significantly higher than the average annual yield of 21,800 doses of bulls in my country. The quality of bull semen i...

Claims

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