Application of compound phytonutrients in the preparation of cellular immune preparations

A technology of phytonutrients and cellular immunity, which is applied in the application field of compound phytonutrients in the preparation of cellular immunity preparations, and can solve problems such as cell damage

Active Publication Date: 2021-06-29
BEIJING DAWN AEROSPACE BIO TECH
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

Most of the anti-tumor drugs currently on the market are synthetic drugs with definite structures, which can cause serious damage to other normal tissue cells while killing tumor tissues

Method used

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  • Application of compound phytonutrients in the preparation of cellular immune preparations
  • Application of compound phytonutrients in the preparation of cellular immune preparations
  • Application of compound phytonutrients in the preparation of cellular immune preparations

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0042] Compound phytonutrients are used to prepare cellular immune preparations, and the compound phytonutrients include 28% by mass of lycopene oleoresin, 19% by mass of grape seed extract, 5% by mass of beeswax, 20% by mass % by mass of soybean oil and 28% by mass of medium chain triglycerides, and the mass content of lycopene in the lycopene oleoresin is 6%.

[0043] (1) Test its antitumor effect on B16 transplanted tumor mice:

[0044] 1. Preparation of 1B16 subcutaneous inhibition mouse model

[0045] Resuscitate B16 melanoma cells by routine methods, expand culture, trypsinize, collect cells, and prepare into 1x10 7 / mL cell suspension, inoculated subcutaneously in the right armpit of C57BL / 6 mice with 0.1 mL.

[0046] 1.2 Grouping and handling of animals.

[0047] 5 days after inoculation, measure the diameter of the mouse transplanted tumor with a vernier caliper, and wait until the tumor grows to 0.2cm3 After that, they were randomly divided into 4 groups: tumor-be...

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Abstract

This application relates to the application of a compound phytonutrient in the preparation of cellular immune preparations, the compound phytonutrient includes lycopene oleoresin with a content of 28% to 42% by mass, and grape seed with a content of 19% to 29% by mass The extract, 3%-5% by mass of beeswax and 24%-50% by mass of vegetable oil, and the mass percentage of lycopene in the lycopene oleoresin is 5%-8%. The above compound phytonutrients can be used to prepare cellular immune preparations that not only have good anti-tumor effects, but also can effectively promote cellular immune functions.

Description

technical field [0001] The invention relates to the field of biomedicine and health, in particular to the application of a compound phytonutrient in the preparation of cellular immune preparations. Background technique [0002] Tumor is one of the most serious diseases that endanger human health, and its incidence is increasing year by year, and tends to be younger. At present, the treatment of tumor mainly adopts traditional treatment methods, such as surgery, radiotherapy, chemotherapy and comprehensive treatment. Chemotherapy began in the 1940s. After decades of development, the total number of anti-tumor drugs has reached hundreds, and the various anti-tumor drugs formulated with these raw materials have reached more than 1,000. Most of the anti-tumor drugs currently on the market are synthetic drugs with definite structures, which can cause serious damage to other normal tissue cells while killing tumor tissues. Contents of the invention [0003] Based on this, it i...

Claims

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Application Information

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Patent Type & Authority Patents(China)
IPC IPC(8): A61K31/00A61K36/87A61P35/00A61P37/04A61K35/644
CPCA61K35/644A61K36/81A61K36/87A61P35/00A61P37/04A61K2300/00
Inventor 牛晨范学文谢瑶路子佳
Owner BEIJING DAWN AEROSPACE BIO TECH
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