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A blood flow measurement apparatus and method

A technology for blood flow and measurement equipment, applied in the field of optoelectronics, can solve problems such as difficult to popularize, reduce system sensitivity, and increase phase noise.

Inactive Publication Date: 2019-01-04
SUN YAT SEN UNIV
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  • Abstract
  • Description
  • Claims
  • Application Information

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Problems solved by technology

However, this method still needs to calculate the flow direction of the blood flow, which makes the calculation too complicated
And because two consecutive concentric circles are not measured at the same time, the accuracy is easily affected by eye movement
In 2013, Blatter et al. built an OCT system based on a Dove prism to achieve simultaneous blood flow measurement with dual beams. However, this method also uses the complex structure of dual detectors and is not easy to popularize.
[0005] The existing technology has realized the time-sharing blood flow measurement of double beams by using an obliquely placed rotating mirror or glass parallel plate, but similar to the scheme proposed by Wang Yimin et al. Signals in each detection direction increase the difficulty of calculation and are easily affected by eye movements
[0006] To sum up, the inventors of the present invention have found that in the existing dual-beam Doppler OCT technology for measuring blood flow, either the two detection beams are time-shared and the accuracy is easily affected by eye movements; or the two detection beams Simultaneous measurement but use two detectors to receive signals in two detection directions respectively, which increases the complexity and cost of the system; The signal detected in the detection direction is only 1 / 4 of the total signal, which reduces the system sensitivity and increases the phase noise
Therefore, there is no perfect technical solution to realize simultaneous measurement of two detection beams and use the same detector to detect signals in two directions at the same time, and it can also ensure that the signal strength in two directions will not weaken

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  • A blood flow measurement apparatus and method

Examples

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no. 1 example

[0056] see Figure 1-4 .

[0057] Such as Figure 1-2 As shown, a blood flow measurement device provided in this embodiment includes: a light source module 100 , a spectroscopic module 200 , a reference arm module 300 , a sample arm module 500 and a detection module 600 .

[0058] The light source module 100 is configured to emit detection light to the spectroscopic module 200 .

[0059] The spectroscopic module 200 is configured to decompose the detection light into a first detection light and a second detection light of a preset ratio, and transmit the first detection light and the second detection light to the reference The arm module 300 and the sample arm module 500.

[0060] Wherein, a first collimating lens is arranged between the spectroscopic module 200 and the reference arm module 300, and a plane mirror is built into the reference module as the reference mirror 303; the spectroscopic module 200 and the sample arm module 500 A second collimating lens 400 is dispo...

no. 2 example

[0095] see Figure 5-7 .

[0096] Such as Figure 5 As shown, this embodiment also provides a blood flow measurement method, which is suitable for execution in the above-mentioned blood flow measurement device, and at least includes the following steps:

[0097] S101. Control the light source module 100 to emit detection light to the spectroscopic module 200, so that the spectroscopic module 200 decomposes the probing light according to a preset ratio and transmits the first probing light and the second probing light to the reference arm module respectively 300 and the sample arm module 500; the reference arm module 300 reflects the first detection light back to the spectroscopic module 200 as a reference light.

[0098] Wherein, a first collimating lens is arranged between the spectroscopic module 200 and the reference arm module 300, and a plane mirror is built into the reference module as the reference mirror 303; the spectroscopic module 200 and the sample arm module 500...

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Abstract

A blood flow measurement apparatus and method are disclosed, the apparatus includes a light source module, a spectroscopic module, a reference arm module, a sample arm module and a detection module. When the optical path is set, the first lens, the rotatable Wollaston prism, the second lens and the delay coding module are simultaneously rotated around the optical path of the optical path of the probe light, so that when the detection light reaches the fundus through the Wollaston prism into two independent detection light beams k1 and k2, the detection light beams k1 and k2 have a fixed included angle alpha regardless of whether the scanning unit is a line scan or a ring scan. The invention utilizes a Wollaston prism and a delay coding module to decompose a beam of detection light into twobeams of detection light which are parallel to each other and have optical path difference, and simultaneously records the frequency shift signals in two detection directions by a detector, so as torealize a single light source and a single detector, and simultaneously collect the blood flow Doppler signals in two directions.

Description

technical field [0001] The invention relates to the field of optoelectronic technology, in particular to a blood flow measuring device and method. Background technique [0002] Studies have shown that abnormal fundus perfusion is closely related to a series of fundus diseases such as diabetic retinopathy, glaucoma, retinal vein occlusion, and age-related macular degeneration. The current gold standard for the detection of retinal vascular-related diseases is fluorescent contrast agent-based fluorescein angiography (FA) and indocyanine angiography (ICGA). However, this fluorescein contrast technique can only observe the distribution and flow information of blood vessels, and cannot obtain blood flow information through calculation. Therefore, developing a technique to measure retinal blood flow is of great significance for the clinical diagnosis, treatment and research of retinal diseases. [0003] Optical coherence tomography (Optical Coherence Tomography, OCT) is a non-in...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61B8/06A61B8/10A61B3/12
CPCA61B3/1233A61B3/1241A61B8/06A61B8/10A61B8/488
Inventor 张军万明明梁姗姗
Owner SUN YAT SEN UNIV