Tuning fork resonant type measurement device and method for platelet contractile force

A tuning fork resonant, measuring device technology, applied in the direction of biological testing, material inspection products, etc., can solve the problems of large blood volume, high cost, low sensitivity and other problems required for detection, and achieve a large temperature control adjustment range, small internal volume, The effect of the detection circuit is simple

Inactive Publication Date: 2019-01-08
ZHEJIANG NORMAL UNIVERSITY
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  • Abstract
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Problems solved by technology

This type of method is expensive, has low sensitivity, and requires a large amount of blood for each test, which is particularly insufficient for pediatric diagnosis

Method used

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  • Tuning fork resonant type measurement device and method for platelet contractile force
  • Tuning fork resonant type measurement device and method for platelet contractile force
  • Tuning fork resonant type measurement device and method for platelet contractile force

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Embodiment Construction

[0033] The present invention will be further described in conjunction with the accompanying drawings and specific embodiments. It should be understood that these examples are only used to illustrate the present invention and are not intended to limit the scope of the present invention. In addition, it should be understood that after reading the content taught by the present invention, those skilled in the art may make various changes or modifications to the present invention, and these equivalent forms also fall within the scope defined in the present application.

[0034] Such as figure 1 As shown, the present invention is based on a tuning fork resonance type platelet contraction force measuring device comprising: a tuning fork sensor 3, a tuning fork holder 2, two lead wires 1 connected to the tuning fork, a miniature cylindrical metal shield 4, a miniature thermostatic sealed warehouse 5, a Measuring blood and reagent injection hole 7, tuning fork excitation and detection...

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Abstract

The invention provides a tuning fork resonant type measurement device and method for platelet contractile force. The tuning fork resonant type measurement device comprises a constant temperature sealing bin, a metal shielding case arranged inside the constant temperature sealing bin, a tuning fork sensor mounted in the metal shielding case, an injection hole, communicated with the interior of themetal shielding case, for blood to be detected and a reagent, a tuning fork driving and detection circuit connected with the tuning fork sensor, a temperature control circuit connected with the constant temperature sealing bin, a microcontroller controlling the tuning fork driving and detection circuit and the temperature control circuit for communication, and an intelligent terminal communicatedwith the microcontroller. The device can accomplish the accurate measurement on the platelet contractile force by only using a trace amount of blood.

Description

technical field [0001] The present invention mainly relates to a measurement technology for rapid detection of platelet contraction force in blood, in particular to a measuring device and method for platelet contraction force of a trace blood sample based on a tuning fork resonance sensor. Background technique [0002] Before the patient undergoes surgery, the doctor must understand the patient's hemostatic function in advance. If the hemostatic function is not perfect, the patient may suffer from heavy bleeding during the operation and cause unexpected situations. Therefore, it is a routine inspection that must be performed to know whether the patient's hemostatic function is defective before the operation. Platelets in the blood play a vital role in the hemostatic response. When the integrity of endothelial cells is compromised, intimal matrix proteins are exposed, triggering rapid platelet adhesion to form a hemostatic plug. Therefore, the comprehensive function test of ...

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): G01N33/49
CPCG01N33/49
Inventor 陈希刘洋陈赵江张筱燕王晖
Owner ZHEJIANG NORMAL UNIVERSITY
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