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Method for preparing Spatholobus granule

A technology of Daxueteng and granules, which is applied in the field of preparation of Daxueteng granules, can solve the problems of affecting the release of active ingredients and the large amount of insoluble matter in Daxueteng granules, and achieve the effect of convenient consumption and low insoluble content

Active Publication Date: 2019-01-25
KANGMEI PHARMA
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

However, in the existing preparation process of Daxueteng granules, there are more insolubles in the obtained Daxueteng granules, which affects the release of active ingredients.

Method used

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  • Method for preparing Spatholobus granule
  • Method for preparing Spatholobus granule
  • Method for preparing Spatholobus granule

Examples

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preparation example Construction

[0023] A preparation method of Daxueteng granules, comprising:

[0024] Steps for preparing materials: choose fresh Sagittarius, soak it in water, wash off the sediment with running water, and set aside;

[0025] Pre-cooking step: Put the dried sagittarius vine into hot water to blanch, then put it into ice water for cold soaking, repeat twice, and take it out;

[0026] Pulverization step: putting S. sagittata into a pulverizer and pulverizing it into S. sagittaria powder, then adding pure water to the S. sagittata powder, and mixing it into a S. sagittaria slurry;

[0027] Homogenizing step: homogenizing the Rhizoma sagittata slurry to obtain the Rhizoma sagittata solution;

[0028] Spray-drying step: after concentrating the Rhizoma sagittata solution, spray-drying treatment is carried out to obtain the mixed granules of Rhizoma sagittata;

[0029] The granulation step: performing second granulation on the fluidized bed of the mixed granules of S. tengensis to obtain S. sat...

Embodiment 1

[0040] A preparation method of Daxueteng granules, comprising:

[0041] Steps for preparing materials: choose fresh Sagittarius, soak it in water, wash off the sediment with running water, and set aside;

[0042] Pre-cooking step: Put the dried vine of Sagittarius into hot water and blanch, the temperature of blanching is 86°C, and the blanching time is 6 minutes, then put it into ice water for cold soaking, the temperature of cold soaking is 0°C, The time for cold soaking is 2 minutes, and the time interval between blanching and cold soaking is 4 minutes. Repeat blanching and cold soaking twice, and take out;

[0043] Crushing steps: Put the Sagittarius in a grinder and crush it into a powder, then add pure water to the powder, the weight ratio of the powder to the purified water is 1:3, and mix it into a powder slurry;

[0044] Filtration step: pass the syringa slurry through a sieve, and the mesh number of the sieve is 100 mesh;

[0045] Homogenization step: Carry out ho...

Embodiment 2

[0049] A preparation method of Daxueteng granules, comprising:

[0050] Steps for preparing materials: choose fresh Sagittarius, soak it in water, wash off the sediment with running water, and set aside;

[0051] Pre-cooking step: Put the dried vine sagittarius into hot water and blanch at a temperature of 89°C for 3 minutes, then soak in ice water at a temperature of 2°C, The time for cold soaking is 4 minutes, and the time interval between blanching and cold soaking is 5 minutes. Repeat blanching and cold soaking twice, and take out;

[0052] Crushing steps: put the Sagittarius in a grinder and crush it into a powder of Sagittarius, then add pure water to the powder of Sagittarius, the weight ratio of the powder of Sagittarius and purified water is 1:4, and mix it into a powder of Sagittarius slurry;

[0053] Filtration step: pass the syringa slurry through a sieve, and the mesh number of the sieve is 100 mesh;

[0054] Homogenization step: Carry out homogenization treatm...

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Abstract

The invention discloses a method for preparing Spatholobus granule. The preparation method comprises the steps of preparing materials, preboiling, pulverizing, homogenizing, spray drying and granulating. The preparation method of the invention forms a complete set of granulating process, and the insoluble matter content in the obtained caulis Sargentodoxae granules is low, the administration is convenient, and the deficiency of the traditional caulis Sargentodoxae granules production technology is overcome.

Description

technical field [0001] The invention relates to the field of traditional Chinese medicine preparations, in particular to a preparation method of Daxueteng granules. Background technique [0002] Sagevine, commonly known as red vine, also known as blood vine, red bark vine, etc. Sagevine is a deciduous, woody vine; the stem is reddish-brown; the compound leaves are three, alternate; the fruit is an aggregate fruit, consisting of multiple fleshy small Berries composition. Mainly produced in Hubei, Sichuan, Jiangxi, Henan, Jiangsu, Anhui and Zhejiang. Bitter in nature and flavor, flat, has heat-clearing and toxic substances removing, promoting blood circulation and dredging collaterals, expelling wind and relieving convulsion. Rheumatic arthralgia, red dysentery, bloody stranguria, irregular menstruation, malnutrition, insect pain, injury from falls. However, in the existing preparation process of Daxueteng granules, the obtained Daxueteng granules contain more insoluble mat...

Claims

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Application Information

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IPC IPC(8): A61K36/185A61K9/16A61P29/00
CPCA61K9/16A61K36/185A61K2236/13A61K2236/15A61K2236/17A61P29/00
Inventor 许冬瑾罗哲李宏锋王文涛张嘉鑫王龙俊黄洁洪
Owner KANGMEI PHARMA
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