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Preparation method for antibacterial contact lens

A contact lens and dopamine technology, applied in the fields of glasses/goggles, optics, instruments, etc., can solve the problems of insufficient antibacterial ability and decreased light transmittance of glasses, and achieve good antibacterial properties, good visible light transmittance, and good biological expansion. sexual effect

Inactive Publication Date: 2019-03-22
SICHUAN PROVINCIAL PEOPLES HOSPITAL
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  • Abstract
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Problems solved by technology

[0005] Aiming at the above-mentioned prior art, the present invention provides a preparation method of antibacterial contact lenses to solve the technical problems of decreased light transmittance and insufficient antibacterial ability of the lenses

Method used

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  • Preparation method for antibacterial contact lens
  • Preparation method for antibacterial contact lens
  • Preparation method for antibacterial contact lens

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Experimental program
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Effect test

Embodiment

[0026] A kind of preparation method of antibacterial contact lens is characterized in that, comprises the following steps:

[0027] (1) Mix the dopamine Tris solution with the silver nitrate solution in a certain ratio to prepare a mixed solution of AgNPs and dopamine;

[0028] (2) Fully stirring and centrifuging the mixed solution of AgNPs and dopamine obtained in step (1), collecting the supernatant to obtain a clear mixed solution of AgNPs and PDA;

[0029] (3) The contact lens was immersed in the supernatant obtained in step (2), and the AgNPs were naturally deposited on the contact lens; at the same time, dopamine was deposited on the contact lens as a biological glue, and the multilayer AgNPs were fixed on the contact lens On the surface, a contact lens product is obtained.

[0030] Among them, in step (1), M 多巴胺 :M Ag+ =0.25~1:1 is the preferred concentration.

[0031] In step (2), the centrifugation rate is above 1500rmp to obtain a clarified supernatant.

[0032]...

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Abstract

The invention discloses a preparation method for an antibacterial contact lens. The method comprises the following steps that firstly, a dopamine Tris solution and a silver nitrate solution are mixedaccording to a certain proportion so as to prepare a mixed solution of AgNPs and dopamine; then the mixed solution is fully stirred and centrifuged, and supernate is collected so as to obtain a clarified mixed solution of the AgNPs and PDA; and then a contact lens body is immersed into the obtained supernate, the AgNPs is naturally deposited on the contact lens body, meanwhile, the dopamine servesas biological glue and is deposited on the contact lens body, and multiple layers of the AgNPs are fixed on the surface of the contact lens body so as to obtain a contact lens finished product. The contact lens prepared through the preparation method has the advantage that the technical problems that the light transmittance of an antibacterial contact lens prepared through a traditional polydopamine silver-loading method is decreased, and the antibacterial capability is insufficient can be effectively solved.

Description

technical field [0001] The invention belongs to the technical field of glasses manufacturing, and in particular relates to a preparation method of an antibacterial contact lens. Background technique [0002] Wearing antibacterial contact lenses is a novel therapy for the prevention and treatment of bacterial and fungal keratitis. Compared with traditional treatment methods such as eye drops and other methods, contact lenses loaded with antibacterial drugs have the advantages of longer-lasting drug sustained release ability and more effective bactericidal effect. For the preparation of contact lenses with antibacterial function, the most important performance requirements are the following two points: (1) good antibacterial effect; (2) good visible light transmittance. [0003] Silver nanoparticles (AgNPs) have broad and potent bactericidal capabilities. Polydopamine (PDA) coatings can be deposited on any material surface. It has been reported that after depositing a PDA c...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): G02C7/04
CPCG02C7/049
Inventor 杨正林刘小琦陈江曲超廖玉珍刘祥琴石毅龚波
Owner SICHUAN PROVINCIAL PEOPLES HOSPITAL
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