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Method for building a model to obtain glomerular filtration rate

A technology of glomerular filtration rate and establishment method, applied in medical simulation, medical informatics, health index calculation, etc., can solve the problem of inaccurate estimation of glomerular filtration rate

Active Publication Date: 2021-11-23
THE THIRD XIANGYA HOSPITAL OF CENT SOUTH UNIV
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  • Application Information

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Problems solved by technology

[0003] The technical problem to be solved by the present invention is: inaccurate estimation of glomerular filtration rate for the Chinese population

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  • Method for building a model to obtain glomerular filtration rate
  • Method for building a model to obtain glomerular filtration rate
  • Method for building a model to obtain glomerular filtration rate

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Embodiment Construction

[0027] In order to make the above objects, features and advantages of the present invention more comprehensible, specific implementations of the present invention will be described in detail below in conjunction with the accompanying drawings. In the following description, numerous specific details are set forth in order to provide a thorough understanding of the present invention. However, the present invention can be implemented in many other ways different from those described here, and those skilled in the art can make similar improvements without departing from the connotation of the present invention, so the present invention is not limited by the specific implementations disclosed below.

[0028] The patient data collected in this specific embodiment comes from the Third Xiangya Hospital (TXH) of Central South University (TXH) and the Second Xiangya Hospital (SXH) of Central South University (Changsha City, Hunan Province) in central China (Changsha City, Hunan Province)...

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Abstract

The present invention relates to a method and application of establishing a model for obtaining the glomerular filtration rate of the Chinese population. The establishment method includes: S1. Multiple candidate independent variables corresponding to the known glomerular filtration rate The least squares linear regression is used for single-factor analysis, and multiple first independent variables are screened out; S2, multiple first independent variables are used for multi-element analysis by multiple linear regression modeling, and the first independent variables are simplified. Quantitatively establish the first model, the function expression of the first model is GFR=94047.95×0.8892828 a ×N ‑0.22630 ×C ‑0 . 52474 × L ‑0 . 92495 ×H 0.28309 ; Among them, GFR represents glomerular filtration rate; a is a sex-related coefficient; C represents the concentration of creatinine; L represents the concentration of chloride ions; H represents the concentration of red blood cells. The model can accurately obtain the glomerular permeability of Chinese patients. The invention also includes the application of a model for obtaining the glomerular filtration rate of the Chinese population in obtaining the glomerular filtration rate of the Chinese population.

Description

technical field [0001] The invention relates to the field of medical and health technologies, in particular to a method for establishing a model for obtaining glomerular filtration rate and its application. Background technique [0002] Kidney disease is a worldwide public health disease with a high incidence and heavy burden. In 2012, there were 120 million chronic kidney disease patients in my country, with an incidence rate of 10.8%. Among hospitalized patients in China, acute kidney injury (AKI) accounted for 2.4%–8.1% of complications, and the mortality rate of patients with acute kidney injury was as high as 18.6%. –28.5%. In China, the average annual treatment cost per dialysis patient is US$14,000. Therefore, rapid and accurate assessment of renal function and changes in renal function is essential for the prevention, diagnosis and treatment of renal diseases. Glomerular Filtration Rate (GFR) is the most accurate indicator for evaluating renal function, but it is d...

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Application Information

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Patent Type & Authority Patents(China)
IPC IPC(8): G16H50/30G16H50/50
CPCG16H50/30G16H50/50
Inventor 左笑丛易翼虎尹文俊李岱阳张毕奎赵军朱超男
Owner THE THIRD XIANGYA HOSPITAL OF CENT SOUTH UNIV