Preparation method of radix angelicae pubescentis formula granules

Abstract

The invention discloses a preparation method of radix angelicae pubescentis formula granules. The preparation method comprises the steps: a, radix angelicae pubescentis medicinal materials are crushedor chopped into coarse granules; b, the coarse granules are continuously input into a continuous countercurrent extracting machine, hot water is continuously and reversely added into the tail ends ofall stages of extraction tubes, continuous dynamic countercurrent extraction is conducted, and extracting solutions, aromatic water and volatile oil are collected respectively; c, the extracting solutions are filtered, ultra-high-temperature instantaneous sterilization is conducted, and filter liquor is concentrated into clear paste; d, the collected radix angelicae pubescentis aromatic water andvolatile oil are ground and included through auxiliary materials, the proper amount of clear paste is added, even mixing is conducted, spray drying is conducted, and thus a radix angelicae pubescentis volatile oil inclusion compound is obtained; e, the clear paste is added into the auxiliary materials to be dissolved, and spray drying is conducted to obtain dry extract powder; and f, the dry extract powder and the radix angelicae pubescentis volatile oil inclusion compound are added into pharmaceutical adjunct, even mixing is conducted, dry granulating is conducted, and thus the radix angelicae pubescentis formula granules are obtained. The preparation method adopts production processes such as continuous countercurrent extracting, high-temperature instantaneous sterilization, volatile oil inclusion and spray drying, all the process parameters are researched, and thus the product quality of the radix angelicae pubescentis formula granules is improved.

Description

technical field

[0001] The invention belongs to the technical field of traditional Chinese medicine formula granules, and in particular relates to a preparation method of Duhuo formula granules. Background technique

[0002] The solitary life is the dry root of Angelica pubescens Maxim.f.biserrata Shanet Yuan. Excavate when the seedlings just germinate in early spring or when the stems and leaves wither in late autumn, remove fibrous roots and sediment, bake until half-dry, pile up for 2 to 3 days, and then dry until completely dry after softening.

[0003] Traditional Chinese medicine formula granules are made by extracting, concentrating, drying, and granulating single-flavored Chinese medicine decoction pieces. The quality level of traditional Chinese medicine formula granules is evaluated based on the consistency of the three major indicators: ointment yield, fingerprint or characteristic map, transfer rate (or content) of main active ingredients and standard decoction ...

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