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Dampness dispelling repair paste and preparation method thereof

A technology of repairing ointment and extract, which is applied in the field of medical and sanitary products, can solve the problems of side effects, low dosage, and no guarantee of safety, and achieve the effect of strong antibacterial effect, high safety, and strong effect

Inactive Publication Date: 2019-04-16
南京紫源康医药科技有限公司
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0009] Among the above-mentioned patents, although the first patent uses a variety of Chinese herbal medicines and has certain effects, it only has a certain activity in the antibacterial aspect, and does not detect the bacteriostatic rate in detail to compare the bacteriostatic effect, and add Two chemically synthesized preservatives, methylparaben and propylparaben, are not used in low amounts, and there are certain sensitization and irritation
[0010] The second patent is also in the antibacterial aspect, relying on chemically synthesized antibacterial agents to achieve antibacterial effects. On February 2, 2017, the US Food and Drug Administration (FDA) released drug safety information: Products containing chlorhexidine gluconate Presence of rare but serious allergic reactions
[0011] Some current eczema creams contain some ingredients that should be used with caution. The safety of use is not guaranteed, which may cause serious side effects, and the skin care effect is ignored.

Method used

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  • Dampness dispelling repair paste and preparation method thereof

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0051] Embodiment 1 a kind of dampness-clearing and repairing ointment

[0052] Formula ingredients (200g), in terms of mass percentage, consist of: 0.5% glycyrrhizinate and its derivatives, 0.02% shikonin, 0.2% Scutellaria baicalensis extract, 0.2% Phellodendron Phellodendri extract, 0.2% Sophora flavescens extract, Paeoniae officinalis extract 0.2%, Magnolia bark extract 0.5%, Snake slough extract 0.2%, Emu oil 10%, Vitamin E 0.2%, Menthol 0.2%, Poloxamer 1884%, Carbomer U200.8% , glycerin 5%, 305 emulsifier 0.5%, glyceryl monostearate 1%, azone 1%, propylene glycol 10%, triethanolamine 0.8%, deionized water is added to 200g.

[0053] Preparation:

[0054] According to the formula quantity, take Poloxamer 188 and Carbomer U20, add part of deionized water, stir at room temperature for 10-40 minutes to dissolve, heat to 80-85°C, stir for 30-40 minutes to fully swell the thickener , then add glycerin, glycyrrhizinate and its derivatives, 305 emulsifier, glyceryl monostearate,...

Embodiment 2

[0055] Embodiment 2 A kind of dampness-clearing and repairing ointment

[0056] Formula ingredients (200g), in terms of mass percentage, consist of: 0.1% of glycyrrhizinate and its derivatives, 0.01% of shikonin, 1% of Scutellaria baicalensis extract, 0.1% of Cortex Phellodendri extract, 1% of Sophora flavescens extract, Paeoniae officinalis extract 0.1%, Magnolia bark extract 1%, Snake slough extract 0.1%, Emu oil 5%, Vitamin E 0.1%, Menthol 0.1%, Poloxamer 1881%, Carbomer U200.4% , glycerin 5%, 305 emulsifier 0.4%, glyceryl monostearate 0.6%, azone 0.5%, propylene glycol 2%, triethanolamine 0.4%, deionized water is added to 200g.

[0057] The preparation method is the same as in Example 1.

Embodiment 3

[0058] Embodiment 3 a kind of dampness-clearing and repairing ointment

[0059] Formula ingredients (200g), in terms of mass percentage, consist of: glycyrrhizinate and its derivatives 1%, shikonin 0.08%, scutellaria baicalensis extract 0.1%, Phellodendron phellodendron extract 1%, Sophora flavescens extract 0.1%, white Paeoniae officinalis extract 1%, Magnolia bark extract 0.1%, Snake slough extract 1%, Emu oil 12%, Vitamin E 0.6%, Menthol 0.5%, Poloxamer 1886%, Carbomer U201%, Glycerin 10%, 2% of 305 emulsifier, 3% of glyceryl monostearate, 1.5% of azone, 10% of propylene glycol, 1% of triethanolamine, deionized water added to 200g.

[0060] The preparation method is the same as in Example 1.

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PUM

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Abstract

The invention discloses a dampness dispelling repair paste and a preparation method thereof. The dampness dispelling repair paste is prepared from, by mass, 0.01-1% of dipotassium glycyrrhizinate andits derivative, 0.01-0.1% of shikonin, 0.05-2% of astragalus membranaceus extract, 0.05-2% of golden cypress extract, 0.05-2% of sophora flavescens extract, 0.05-2% of white paeony root extract, 0.05-2% of magnolia bark extract, 0.05-2% of snake slough extract, 1-15% of emu oil, 0.05-1% of vitamin E, 0.05-0.5% of menthol, 5.2-44% of an assistant and the balance deionized water. The invention alsodiscloses a preparation method thereof. The dampness dispelling repair paste has the effects of inhibiting bacteria, astringing, relieving itching, subsiding swelling, preventing exudation and relieving inflammations, contains no hormonal and chemically synthesized antiseptic and antibacterial ingredients, is suitable for eczema and all kinds of irritations, itching and redness caused by skin allergy, mosquito bites and the like.

Description

technical field [0001] The invention belongs to the technical field of medical and sanitary products, and in particular relates to a dampness-clearing and repairing ointment and a preparation method thereof. Background technique [0002] Eczema is an inflammatory response skin disease, usually stimulated by external factors or caused by internal factors. It belongs to the category of "wet sore" and "soaked sore" in traditional Chinese medicine. The skin lesions are generally distributed symmetrically and diversely. They often have obvious exudation tendency, may have itching sensation, recurrent attacks, lingering and difficult to heal, and easily evolve into chronic eczema. People of all ages can suffer from the disease, and there is no obvious gender difference. It is more common in people with allergic constitution. [0003] According to the theory of traditional Chinese medicine, eczema is called eczema. The pathogenesis is that the spleen is not healthy, and it is not ...

Claims

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Application Information

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IPC IPC(8): A61K36/756A61K9/06A61P17/00A61P17/02A61P17/04A61P29/00A61P31/02A61P31/04A61P37/08A61K31/045A61K31/122A61K31/355A61K31/704A61K35/57A61K35/583
CPCA61K9/0014A61K9/06A61K31/045A61K31/122A61K31/355A61K31/704A61K35/57A61K35/583A61K36/489A61K36/539A61K36/575A61K36/65A61K36/71A61K36/756A61K2236/333A61K2236/53A61P17/00A61P17/02A61P17/04A61P29/00A61P31/02A61P31/04A61P37/08A61K2300/00
Inventor 魏元刚钟慧杨永安易铭金显友
Owner 南京紫源康医药科技有限公司
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