A three-fluorescence-emitting molecularly imprinted sensor and its preparation and application

A technology of molecular imprinting and fluorescence emission, which is applied in the field of analytical chemistry and rapid detection, can solve the problems of inability to accurately visualize the detection target, complex optimization process of emission peak intensity ratio, narrow range of fluorescence color change, etc., to achieve rich fluorescence color change , reduce experiment cost and shorten experiment period
CN109655442BActive Publication Date: 2019-06-11YANTAI INST OF COASTAL ZONE RES CHINESE ACAD OF SCI
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Patent Information

Authority / Receiving Office
CN · China
Patent Type
Patents(China)
Current Assignee / Owner
YANTAI INST OF COASTAL ZONE RES CHINESE ACAD OF SCI
Publication Date
2019-06-11

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Abstract

The invention belongs to the field of analytical chemistry and quick detection, and particularly relates to a red-green-blue tri-fluorescent emission molecularly imprinted sensor based on a post-imprinting mixing method and a preparation method and application thereof in accurately and visually detecting hemoglobin. The red-green-blue tri-fluorescent emission molecularly imprinted sensor is obtained by mixing red fluorescent bovine hemoglobin imprinted microspheres, green fluorescent bovine hemoglobin imprinted microspheres and blue fluorescent bovine hemoglobin imprinted microspheres throughthe post-imprinting mixing method. The sensor prepared by the method can detect bovine hemoglobin in a high-sensitivity, high-selectivity and self-correcting manner, and the sensor is wider and richerthan conventional dual-fluorescent emission molecularly imprinted sensors in fluorescent color changing range and can visually detect a target more accurately.
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Description

technical field

[0001] The invention belongs to the fields of analytical chemistry and rapid detection, in particular to a red-green-blue three fluorescence emission molecular imprint sensor based on a post-imprint hybrid method and its preparation and application in accurate visual detection of bovine hemoglobin. Background technique

[0002] Nowadays, rapid visual inspection plays an important role in environmental inspection, food safety, clinical diagnosis and other fields. The rapid visual detection of a large number of samples to be tested, combined with the accurate detection of suspicious samples by large-scale instruments (such as high performance liquid chromatography), often constitute a complete detection process, which not only saves the money and time of detection, but also ensures the reliability of the detection results. Therefore, rapid visual detection methods with high sensitivity and high selectivity are often required.

[0003] The ratiometric fluoresce...

Claims

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