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Liver-protecting traditional Chinese medicine compound prescription

A technology of traditional Chinese medicine and compound prescription is applied in the field of liver-protecting traditional Chinese medicine compound and its preparation, and achieves the effects of small batch-to-batch variation, controllable operation steps, and high content of crude drug components

Inactive Publication Date: 2019-07-19
南京和昌睿生物科技有限公司
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

However, how to control liver fibrosis is still an international problem, and it is urgent to develop safe and effective anti-hepatic fibrosis drugs clinically

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0028] A liver-protecting traditional Chinese medicine compound, comprising the following components in parts by weight: 30 parts of nasturtium, 15 parts of milk thistle, 10 parts of dogwood stalk, 10 parts of lathyrus pilose, 5 parts of licorice, and 5 parts of small-leaf fragrant tea 5 parts and 5 parts of Zhuzhucao.

[0029] The medicinal part of the nasturtium is the flower; the medicinal part of the dogwood with stalk is the stem bark; the medicinal part of the Lathyrus pilosa is the aerial part; part.

[0030] A preparation method of liver-protecting traditional Chinese medicine compound, characterized in that: comprising the following steps:

[0031] S01, take the dried milk thistle, cornel sylvestris, licorice, small-leaf chrysanthemum, and pearl grass in the above parts by weight, add 8 times the amount of 60% ethanol and heat reflux extraction for 3 times, each extraction for 1 hour, and combine The extract is filtered, and the filtrate is concentrated until it has...

Embodiment 2

[0038] A liver-protecting traditional Chinese medicine compound, comprising the following components in parts by weight: 10 parts of nasturtium, 25 parts of milk thistle, 20 parts of cornus officinalis, 20 parts of lathyrus pubescent and 15 parts of licorice. 10 parts of small-leaf fragrant tea and 10 parts of pearl grass.

[0039] The medicinal part of the nasturtium is the flower; the medicinal part of the dogwood with stalk is the stem bark; the medicinal part of the Lathyrus pilosa is the aerial part; part.

[0040] A preparation method of liver-protecting traditional Chinese medicine compound, comprising the following steps:

[0041] S01, take the dried milk thistle, cornel pedunata, licorice, small-leaved chrysanthemum and syringa in the above parts by weight, add 15 times the amount of 80% ethanol and heat-reflux extract 5 times, extract 2 hours each time, and combine The extract is filtered, and the filtrate is concentrated until it has no alcohol smell, then the con...

Embodiment 3

[0046] A liver-protecting traditional Chinese medicine compound, comprising the following components in parts by weight: 20 parts of nasturtium, 20 parts of milk thistle, 15 parts of dogwood with stalk, 15 parts of lathyrus vellus, 10 parts of licorice, and 8 parts of lobular tea 8 servings and 8 servings of bead grass.

[0047] The medicinal part of the nasturtium is the flower; the medicinal part of the dogwood with stalk is the stem bark; the medicinal part of the Lathyrus pilosa is the aerial part; part.

[0048] A preparation method of liver-protecting traditional Chinese medicine compound, comprising the following steps:

[0049] S01, take the dried milk thistle, cornel sylvestris, licorice, small-leaf chrysanthemum, and pearl grass in the above weight parts, add 10 times the amount of 70% ethanol and heat reflux extraction 4 times, each time for 1.5 hours, and combine The extract is filtered, and the filtrate is concentrated until it has no alcohol smell, then the con...

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PUM

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Abstract

The invention discloses a liver-protecting traditional Chinese medicine compound prescription. The liver-protecting traditional Chinese medicine compound prescription consists of the following ingredients in parts by weight: 10-30 parts of flowers of Chinese globeflower, 15-25 parts of milk thistle, 10-20 parts of melicope patulinervia with stalks, 10-20 parts of lathyrus palustris, and 5-15 partsof liquorice roots. The invention further discloses a preparation method of the liver-protecting traditional Chinese medicine compound. The preparation method of the liver-protecting traditional Chinese medicine compound comprises the following steps: S01, preparing alcohol-extracted dry powder; S02, preparing water-extracted dry powder; and S03, uniformly mixing the alcohol-extracted dry powderwith the water-extracted dry powder so as to obtain a final product. The liver-protecting traditional Chinese medicine compound prescription disclosed by the invention has the effects of treating liver fibrosis, acute and chronic hepatitis as well as hepatic adipose infiltration, and preventing liver cancer; moreover, the preparation method of the liver-protecting traditional Chinese medicine compound prescription is controllable in operation steps, small in inter-batch differences, and suitable for industrial production. In addition, high purity medicinal parts can be obtained with high content of effective crude drug components achieved; moreover, the effects of reducing toxicity and enhancing efficacy can also be achieved.

Description

technical field [0001] The invention relates to a liver-protecting traditional Chinese medicine compound and a preparation method thereof, belonging to the technical field of traditional Chinese medicine compound. Background technique [0002] Liver fibrosis is the common pathological basis for the development of various chronic liver diseases (acute and chronic hepatitis, fatty liver, liver cancer, etc.) to cirrhosis. Lots of deposits. The continuous development of liver fibrosis leads to corresponding organ dysfunction and failure, which seriously endangers life and health. Slowing down, preventing or even reversing liver fibrosis is of great significance to reducing the occurrence of serious complications, improving the quality of life of patients and increasing the survival rate. [0003] There are many etiologies of liver fibrosis, and the pathogenesis is intricate. Liver fibrosis is a dynamic pathological process, including multiple stages of occurrence, development...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/75A61P1/16A61P35/00
CPCA61K36/28A61K36/47A61K36/48A61K36/484A61K36/53A61K36/71A61K36/75A61K2236/331A61K2236/333A61K2236/39A61K2236/51A61K2236/53A61K2236/55A61P1/16A61P35/00A61K2300/00
Inventor 张娟
Owner 南京和昌睿生物科技有限公司
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