Looking for breakthrough ideas for innovation challenges? Try Patsnap Eureka!

Application of clostridium butyricum for preparing preparation for preventing or treating cholangiocarcinoma

A technology of Clostridium butyricum and cholangiocarcinoma, applied in the field of biomedicine, can solve the problems of insignificant clinical symptoms, multiple lesions, and poor prognosis of cholangiocarcinoma

Inactive Publication Date: 2019-08-06
QINGDAO EASTSEA PHARMA
View PDF2 Cites 1 Cited by
  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0002] As a common malignant tumor of the biliary tract, cholangiocarcinoma is the second largest primary hepatobiliary malignant tumor after liver cancer. Due to its anatomical location, growth characteristics and lack of exact diagnostic criteria, early diagnosis is difficult, and the clinical symptoms are not obvious and Limited treatment options make the prognosis extremely poor
[0003] In recent years, the incidence rate of cholangiocarcinoma has been increasing year by year. Surgical resection is the first choice for the treatment of cholangiocarcinoma. Most patients are already in the advanced stage of cancer when they are diagnosed, so the 5-year survival rate is less than 10%, and about 80% of cholangiocarcinoma can only be treated with palliative treatment due to metastasis or advanced stage, and the effect of existing treatment drugs is not satisfactory

Method used

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
View more

Examples

Experimental program
Comparison scheme
Effect test

preparation Embodiment 1

[0032] Preparation Example 1 The preparation of Clostridium butyricum powder

[0033] 1 Preparation of bacteria powder and identification of strains

[0034] Take a human feces sample, then put the sample in a sterilized anaerobic bottle, blow in nitrogen gas and mix well at the same time, quickly take 2 grams of sample from it and add it to 18 mL of sterilized diluent, blow in nitrogen gas and mix well at the same time, In the bacteria operating table, carry out 10 -1 、10 -2 、10 -3 、10 -4 , 10 -5 , 10 -6 , 10 -7 Gradient dilution, take 10 -5 , 10 -6 , 10 -7Three dilution gradients were spread on the solid medium for the selective single colony isolation of Clostridium butyricum, placed in an anaerobic tank, cultured at 37°C for 48 hours, and selected single colonies with good growth were inoculated in the liquid amplification In the culture medium, place it in an anaerobic tank, and anaerobically expand and cultivate at 37° C. for 48 hours. Centrifuge the obtained ...

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
Login to View More

PUM

PropertyMeasurementUnit
Total viable bacteriaaaaaaaaaaa
Login to View More

Abstract

The invention discloses an application of clostridium butyricum for preparing preparation for preventing or treating cholangiocarcinoma. Specifically, clostridium butyricum is a main active ingredient, and a biological preparation such as a medicine is prepared, and invention provides the application of clostridium butyricum in the prevention or treatment of cholangiocarcinoma, which belongs to the field of biomedicine.

Description

technical field [0001] The invention relates to the application of clostridium butyricum in the preparation of preparations for preventing or treating cholangiocarcinoma, in particular to using clostridium butyricum to prevent or treat cholangiocarcinoma and belongs to the field of biomedicine. Background technique [0002] As a common malignant tumor of the biliary tract, cholangiocarcinoma is the second largest primary hepatobiliary malignant tumor after liver cancer. Due to its anatomical location, growth characteristics and lack of exact diagnostic criteria, early diagnosis is difficult, and the clinical symptoms are not obvious and Limited treatment options make the prognosis extremely poor. [0003] In recent years, the incidence of cholangiocarcinoma has been increasing year by year. Surgical resection is the first choice for the treatment of cholangiocarcinoma. Most patients are already in the advanced stage of cancer when they are diagnosed, so the 5-year survival ...

Claims

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
Login to View More

Application Information

Patent Timeline
no application Login to View More
IPC IPC(8): A61K35/742A61P35/00A23L33/135A23L2/38
CPCA61K35/742A23L33/135A23L2/38A23V2002/00A23V2200/308
Inventor 崔云龙李洪福赵婀姿
Owner QINGDAO EASTSEA PHARMA
Who we serve
  • R&D Engineer
  • R&D Manager
  • IP Professional
Why Patsnap Eureka
  • Industry Leading Data Capabilities
  • Powerful AI technology
  • Patent DNA Extraction
Social media
Patsnap Eureka Blog
Learn More
PatSnap group products

Browse by: Latest US Patents, China's latest patents, Technical Efficacy Thesaurus, Application Domain, Technology Topic, Popular Technical Reports.

© 2024 PatSnap. All rights reserved.Legal|Privacy policy|Modern Slavery Act Transparency Statement|Sitemap|About US| Contact US: help@patsnap.com