Experimental device for mouse exhaled droplet transmission of pathogens

Abstract

The invention discloses an experimental device for mouse exhaled droplet transmission of pathogens. Cross contamination between experimental mice of a transmission group in the experimental process can be avoided, and the mice infected by transmission get diseases through pathogens in the form of exhaled droplets, and can be infected for a long time. The technical scheme is characterized in that the device comprises a casing and a central chamber, wherein a partition plate is arranged in the central chamber and divides the central chamber into an upper chamber and a lower chamber; the upper chamber is configured to accommodate the experimental mice of the transmission group, and a plurality of mouse cages are arranged in the upper chamber; each mouse cage comprises a top wall plate, a bottom plate and side wall plates, the bottom plates face the partition plate and are arranged in parallel with the partition plate, holes are formed in the top wall plates and the bottom plates, and theside wall plates are all closed plates; the low chamber is configured to accommodate bacterium-carrying mice of an infection group; through holes communicated with the upper chamber and the lower chamber respectively are formed in the partition plate; a diffusion port communicated with the upper chamber is formed in the upper wall of the casing. By means of the technical points, cross infection ofthe experimental mice of the transmission group in all mouse cages is avoided, and experiment accuracy can be improved.

Description

technical field [0001] The invention relates to a cage for animals, in particular to a mouse-used experimental device for exhaled droplet transmission of pathogens, which can be used for droplet transmission experiments of rats and to prevent cross-infection between experimental mice in transmission groups. Background technique [0002] Inhalation Toxicology is a science that studies the various conditions, laws and mechanisms of the occurrence, development and elimination of the toxic effects of inhalable substances on the body, as well as the risk assessment of inhalable substances. His professional research contents mainly include: the physical and chemical properties of various substances in the air; the basic biology of the respiratory tract; the deposition and retention of inhaled substances in the body and their interactions with important systems and organs in the body, and how these effects lead to diseases of. With the increasingly active international research on...

AI Technical Summary

Problems solved by technology

For example, in some existing inhalation toxicology studies, healthy animals such as mice are placed in a cage together with the mice carrying the disease, and the breath exhaled by the mice carrying the disease is used for the breathing of the healthy mice to carry out inhalation exposure Experiments, but each time the virus was exposed, multiple healthy mice and mice with diseased bacteria were placed in the cage at the same time, which could not be isolated, and there would be body collisions between each other, resulting in cross-infection, which would affect the experiment. result

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