Irradiated cross-linked hyaluronic acid hydrogel medical cold compress patch

A cross-linked hyaluronic acid and hydrogel technology, applied in the field of medical supplies, can solve the problems of poor cosmetic effect, skin moisture, elasticity, smoothness and wrinkle effect, etc., to reduce skin wrinkles and enhance skin smoothness , enhance the effect of skin moisture

Inactive Publication Date: 2019-08-16
江苏达胜伦比亚生物科技有限公司
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

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Problems solved by technology

[0003] The Chinese patent application number is ZL 201410190594.7, a hydrogel cold patch, the formula includes the following components: 65-75% starch, 17-23% polyvinylpyrrolidone, 8-12% carboxymethyl cellulose Sodium and enough solvents to fully dissolve other components can physically cool the skin by 2°C and have a good soothing and analgesic effect on tumor patients. Its use time is about 15 minutes. Although a hydrogel co

Method used

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  • Irradiated cross-linked hyaluronic acid hydrogel medical cold compress patch
  • Irradiated cross-linked hyaluronic acid hydrogel medical cold compress patch

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0019] (1) Weigh 9% palm petiole extract, 6% polyvinylpyrrolidone, 4% cellulose gum, 4% hyaluronic acid and 77% medical purified water and add them to the stirring tank, stir to form a hydrogel , the stirring temperature is 90°C, and the stirring time is 120min;

[0020] (2) Coating the hydrogel in step (1), and cutting the coating into upper and lower split type cold compresses by a cutting and packaging machine;

[0021] (3) Pack the cold compress into an aluminum foil bag, place the aluminum foil bag in an aluminum tray, and then irradiate it with a dose of 30Gy electron beams.

Embodiment 2

[0023] (1) Weigh 10% palm petiole extract, 5% polyvinylpyrrolidone, 3% cellulose gum, 7% hyaluronic acid and 75% medical purified water and add them to the stirring tank, stir to form a hydrogel , the stirring temperature is 90°C, and the stirring time is 120min;

[0024] (2) Coating the hydrogel in step (1), and cutting the coating into upper and lower split type cold compresses by a cutting and packaging machine;

[0025] (3) Pack the cold compress into an aluminum foil bag, place the aluminum foil bag in an aluminum tray, and then irradiate it with a dose of 35Gy electron beams.

Embodiment 3

[0027] (1) Weigh five raw materials of 8% palm petiole extract, 8% polyvinylpyrrolidone, 5% cellulose gum, 3% hyaluronic acid and 76% medical purified water into the stirring tank, and stir to form a hydrogel , the stirring temperature is 90°C, and the stirring time is 120min;

[0028] (2) Coating the hydrogel in step (1), and cutting the coating into upper and lower split type cold compresses by a cutting and packaging machine;

[0029] (3) Pack the cold compress into an aluminum foil bag, place the aluminum foil bag in an aluminum tray, and then irradiate it with a dose of 20Gy electron beams.

[0030] The palm petiole extract used in Examples 1 to 3 of the present invention is a white powdery starch starch processed from flax palm logs through processes such as peeling, cutting, grinding, product washing and separation, starch extraction, refining, dehydration and drying, The pH is 5.0-7.0, the water content is 11-14%, the gray value is not more than 0.3%, the starch value...

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Abstract

The invention discloses an irradiated cross-linked hyaluronic acid hydrogel medical cold compress patch. A formula comprises the following components by the mass percentage: 8%-10% of a palm petiole extract, 5%-8% of a cross-linking agent, 3%-5% of cellulose gum, 0.1%-7% of hyaluronic acid and water enough to fully dissolve other components. By the method, the application time of the hydrogel product can be prolonged from the original of 45 min to about 2 h, the skin humidity can be increased rapidly, the skin elasticity can be increased, the skin smoothness can be enhanced and the skin wrinkles can be reduced, and better effects can be achieved in repair after various kinds of cosmetic surgeries and daily skin care.

Description

technical field [0001] The invention relates to the technical field of medical supplies, in particular to an irradiation-crosslinked hyaluronic acid hydrogel medical cold compress. Background technique [0002] Medical hydrogels are mainly gel-like materials composed of deionized water plus some polymer copolymers and cross-linking agents. There are many types and can be used in the fields of medicine and surgery. For example, hydrogels Instead of traditional gauze as a wound dressing, because the gel state of the hydrogel itself is softer than traditional gauze, it can also absorb wound secretions, reduce the chance of wound infection, and reduce patient pain. [0003] The Chinese patent application number is ZL 201410190594.7, a hydrogel cold patch, the formula includes the following components: 65-75% starch, 17-23% polyvinylpyrrolidone, 8-12% carboxymethyl cellulose Sodium and enough solvents to fully dissolve other components can physically cool the skin by 2°C and hav...

Claims

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Application Information

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IPC IPC(8): A61F7/02A61L15/28A61L15/40
CPCA61F7/02A61L15/28A61L15/40C08L5/08C08L1/00
Inventor 李倩肖峰林家财武传业
Owner 江苏达胜伦比亚生物科技有限公司
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