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Traditional Chinese medicine scald ointment for treating burn and scald, and preparation method of traditional Chinese medicine scald ointment

A scald ointment and a technology for burns and scalds, which are applied in the directions of pharmaceutical formulations, medical preparations without active ingredients, and medical preparations containing active ingredients, etc. The effect of dissolving scab and facilitating drainage

Inactive Publication Date: 2019-08-16
白冰
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

However, the preparation forms of traditional Chinese medicine formulas are different, and it is inconvenient to use

Method used

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  • Traditional Chinese medicine scald ointment for treating burn and scald, and preparation method of traditional Chinese medicine scald ointment
  • Traditional Chinese medicine scald ointment for treating burn and scald, and preparation method of traditional Chinese medicine scald ointment
  • Traditional Chinese medicine scald ointment for treating burn and scald, and preparation method of traditional Chinese medicine scald ointment

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0032] A traditional Chinese medicine scald ointment for treating burns and scalds, which is made of the following components:

[0033] Water phase composition: 15g sodium lauryl sulfate, 80mg glycerin, 1.5g ethyl p-hydroxybenzoate, 750ml purified water;

[0034] Composition of oil phase: 150g white petrolatum, 100ml paraffin, 150g stearyl alcohol;

[0035] Composition of traditional Chinese medicine: comfrey 10g, rhubarb 10g, Phellodendron 10g, Huanglian 10g, Burnet 10g, Angelica dahurica 10g, frankincense 10g, myrrh 10g, borneol 6g.

[0036] According to another object of the present invention, the present invention provides the following technical solutions:

[0037] A preparation method of a traditional Chinese medicine scald ointment for the treatment of burns, comprising the steps of:

[0038] S1, take comfrey, rhubarb, Phellodendron cortex, Coptis chinensis, Burnet, Angelica dahurica, frankincense, myrrh and borneol according to proportioning weight, borneol is pulver...

Embodiment 2

[0042] Embodiment 2 Toxicological tests relevant to the present invention

[0043] In order to ensure medication safety, the Chinese medicine scald ointment of Example 1 prepared by the present invention was used to carry out acute toxicity test, skin allergy test, and skin irritation test. Change, no irritation and sensitization to the skin and other toxic side effects.

[0044] 1 Acute toxicity test

[0045] (1) Medicine: the traditional Chinese medicine scald ointment made by Preparation Example 1.

[0046] (2) Animals: 10 New Zealand white rabbits, weighing 2.0 ± 0.2 kg, provided by the Experimental Animal Center of Shandong University of Traditional Chinese Medicine.

[0047] (3) Method: The animals were randomly divided into two groups, with 2 animals in each group. Disposable smear administration after skin depilation, medicine group gives Chinese medicine scald ointment 2ml of the present invention, control group gives distilled water of same volume, makes Chinese m...

Embodiment 3

[0066] Embodiment 3 Chinese medicine preparation pharmacodynamics test report of the present invention

[0067] For observing the efficacy of Chinese medicine scald ointment of the present invention, carried out in vitro bacteriostasis test and anti-inflammatory test, the result shows that Chinese medicine scald ointment of the present invention has antibacterial action in various degrees to escherichia coli, Staphylococcus aureus, Neisseria gonorrhoeae, and Has a strong anti-inflammatory effect.

[0068] 1 In vitro antibacterial test

[0069] (1) Medicine: the ointment made by Preparation Example 1.

[0070] (2) Culture medium: MH medium, Sabao weak agar medium, chocolate agar medium.

[0071] (3) Experimental strains: 5 strains each of Staphylococcus aureus, Escherichia coli, and Neisseria gonorrhoeae, provided by China Institute for the Control of Pharmaceutical and Biological Products.

[0072] (4) method: Chinese medicine ointment of the present invention is diluted in...

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Abstract

The invention discloses traditional Chinese medicine scald ointment for treating burn and scald, and a preparation method of the traditional Chinese medicine scald ointment. The traditional Chinese medicine scald ointment is prepared from an aqueous phase, an oil phase and traditional Chinese medicine components, wherein the aqueous phase is prepared from 15g of sodium dodecyl sulfate, 80mg of glycerol, 1.5g of ethyl 4-hydroxybenzoate and 750ml of purified water; the oil phase is prepared from 150g of white vaseline, 100ml of paraffin and 150g of octadecanol; the traditional Chinese medicine components comprise 10g of radix arnebiae seu lithospermi, 10g of radix et rhizoma rhei, 10g of cortex phellodendri, 10g of rhizoma coptidis, 10g of radix sanguisorbae, 10g of radix angelicae dahuricae, 10g of frankincense, 10g of myrrh and 6g of borneol. The effective components of the traditional Chinese medicine scald ointment are pure traditional Chinese medicines, are extracted by using a reasonable technology and are added into matrix; the traditional Chinese medicine scald ointment inherits the effective treatment technique of antisepsis and anti-inflammation as well as necrotic tissue removal and granulation promotion, realizes maximum healing, eliminates scars and reduces infection to the utmost extent under the condition that no side effect is caused, has a good treatment effect on burn and scald as well as bedsore and ulcerative wound, and avoids the irritation of modern chemical agents, drug resistance and inconvenience of use of the traditional Chinese medicine preparations.

Description

technical field [0001] The invention relates to the technical field of traditional Chinese medicine for treating burns, in particular to a traditional Chinese medicine scald ointment for treating burns and a preparation method thereof. Background technique [0002] Burns and scalds are common traumas in daily life. At present, there are many kinds of medicines for treating burns and scalds, which are basically divided into traditional Chinese medicine and western medicine. medicinal properties or side effects. Traditional Chinese medicine formula has many advantages in the treatment of burns and scalds, and the effect is good. However, the preparation forms of traditional Chinese medicine formulas are different, and it is relatively inconvenient to use. [0003] In the process of treating burns and scalds, the use of ointment has certain advantages, such as easy operation and obvious effect. However, the existing drugs for treating burns and scalds have the disadvantages o...

Claims

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Application Information

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IPC IPC(8): A61K36/756A61K9/06A61P17/02A61K31/045
CPCA61K9/0014A61K9/06A61K31/045A61K36/232A61K36/30A61K36/324A61K36/328A61K36/708A61K36/718A61K36/739A61K36/756A61K47/20A61K2236/333A61P17/02A61K2300/00
Inventor 白冰
Owner 白冰
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