Composite preparation for preventing and controlling aquatic animal parasites

A kind of composite technology for aquatic animals, which is applied in the direction of drug combination, medical preparations with non-active ingredients, medical preparations containing active ingredients, etc., to achieve the effect of improving the mixing degree, facilitating market promotion, and suppressing volatilization

Inactive Publication Date: 2019-08-16
金华市呗力水产养殖技术有限公司
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

However, there are few reports on the application of chlorantraniliprole in the control of aquatic parasites

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0043] Produce a kind of powder type compound preparation, each component distribution ratio is:

[0044] Add 3% (weight) deltamethrin;

[0045] Add 35% (weight) plant essential oil (matrine essential oil and citronella essential oil mix by weight 1:1);

[0046] Add 35% (weight) cornstarch;

[0047] Add 20% (weight) talcum powder;

[0048] Add 2.5% (weight) boron nitride;

[0049] Add 4.5% (weight) polyethylene glycol 400;

[0050] The formula mixture is ultrafinely pulverized, dried and sieved to obtain the product.

Embodiment 2

[0052] Produce a kind of water dispersible granule compound preparation, each component distribution ratio is:

[0053] Adding 5% (weight) concentration is 6% chlorantraniliprole;

[0054] Add 32% (weight) cinnamon essential oil and clove essential oil; The two mix by weight 2:1;

[0055] Add 2% (weight) polysorbate 20;

[0056] Add 5% (weight) NNO;

[0057] Add 4% (weight) sodium methyl starch;

[0058] Add 3% (weight) OP-10;

[0059] Add 0.5% (weight) carboxymethylcellulose;

[0060] Add 42.5% (weight) mica;

[0061] Add 6% (weight) 2-octyl dodecanol; Contain volume percentage 0.6% sphingosine and 0.01% glyceroglycolipid in 2-octyl dodecanol; Sphingosine and glyceroglycolipid play a role synergistically, can promote The penetrant molecule carries the insecticidal active ingredient quickly into the parasite, or penetrates the cell membrane of the cell, or penetrates the cyst of the sporozoite, increasing the killing rate of the parasite;

[0062] The formula material m...

Embodiment 3

[0073] Adopt the composite preparation in the embodiment of the present invention 2 to carry out fish parasite killing test:

[0074] Using the static indoor test method, put aerated and dechlorinated tap water in a group of aquariums, with an effective volume of 50L, pH7.2, D0 greater than 5mg / L, hardness of 8.5 German degrees, and a test water temperature of 28 degrees Celsius. The sick fish of parasite moves in the aquarium, every case 10. Four concentration groups were set up in the test, which were compound preparations of 0.2mg / L, 0.4mg / L, 0.6mg / L, and 0.8mg / L respectively, and a blank control group was also set up. Continuously observe for 3 days after the application of the drug, and reflect the insecticidal activity of the drug by the living conditions of the parasites.

[0075] After 3 days of the test, the trichomonas on the gills of the diseased fish in the 0.2mg / L group were reduced by 73%, the number of trichomonas in the 0.4mg / L treatment group was reduced by 9...

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Abstract

The invention provides a composite preparation for preventing and controlling aquatic animal parasites. The composite preparation comprises a) at least one synthetic chemical insecticide and b) at least two plant essential oils. A method for mixing at least two plant essential oils comprises the following steps: sequentially adding the plant essential oils into liquid n-butane at the temperature of minus 4 DEG C to minus 0.5 DEG C, fully stirring, then adding tert-butyl peroxide, and fully stirring; introducing ultrasonic waves into the obtained product at the temperature of minus 4 DEG C to minus 1 DEG C, adjusting the power of the ultrasonic waves until the solution is in a half-boiling state, maintaining for 0.5 to 1 hour, stopping the ultrasonic waves, adding n-butane at the temperature of minus 4 DEG C and keeping the temperature for 0.1 to 0.5 hour; repeating the previous step 2-3 times; and filtering, standing and extracting the obtained product to obtain the mixed plant essential oil. The composite preparation disclosed by the invention is non-toxic, does not pollute the environment, is not easy to generate resistance, and has effects of destroying a cell membrane structureor destroying intracellular Ca2+ balance, and an effect of killing harmful microorganisms and parasites is achieved.

Description

technical field [0001] The invention belongs to the field of prevention and treatment of aquatic animal parasites, and in particular relates to a compound preparation for preventing and controlling aquatic animal parasites. Background technique [0002] my country is a big country in the aquaculture industry, and aquatic animal parasitic diseases are an important factor affecting the economic benefits of aquaculture industry. Among them, the more harmful aquatic animal parasites include trichomonas and ringworms; fish parasitic diseases are one of the main diseases in the fish farming industry, and their epidemic areas are wide and long-term, which can cause a large number of fish deaths . In the past, the use of pesticides and heavy metal salts in aquaculture to control fish parasitic diseases was effective, but with the passage of time, drug resistance continued to emerge. At the same time, these drugs have cumulative residual effects on aquatic organisms, which can caus...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K45/06A61K36/61A61K36/899A61K47/02A61K47/04A61K47/36A61K47/12A61K47/18A61K47/26A61P33/02A61P33/10A61P33/14A61K31/4439A61K31/277A61K31/4375
CPCA61K31/277A61K31/4375A61K31/4439A61K36/54A61K36/61A61K36/899A61K45/06A61K47/02A61K47/12A61K47/18A61K47/26A61K47/36A61P33/02A61P33/10A61P33/14A61K2300/00
Inventor 孙弋博
Owner 金华市呗力水产养殖技术有限公司
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