Nutritional composition for improving cell membranes

A nutritional composition, cell membrane technology, applied in the field of infant nutrition, can solve problems such as no longer-term effects mentioned

Pending Publication Date: 2019-08-27
NV NUTRICIA
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

In all cases, immediate dietary effects are disclosed, but longer-term effects are not mentioned

Method used

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  • Nutritional composition for improving cell membranes
  • Nutritional composition for improving cell membranes
  • Nutritional composition for improving cell membranes

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0202] Example 1: Synergistic effect of sn-2 palmitic acid and lipid globule design on brain fatty acid composition later in life

[0203] The following experiments were carried out in which the effect of infant formula (IMF) comprising standard vegetable lipids was compared with IMF of the present invention, the lipid component of which comprises palmitic acid with an increased amount at its sn-2 position. Triglycerides, and / or lipid globules that increase in size and contain increased amounts of phospholipids.

[0204] The offspring of C57 / BL6 dams were exclusively breastfed until postnatal day 16. Beginning on day 16, dams and their offspring were exposed to the experimental diet. From day 16 to day 21 after birth, the offspring were mainly fed the experimental diet, but were also allowed to drink breast milk. From day 21 onwards, the offspring were fed exclusively on the experimental diet. The experimental diet was provided in dough form and exposure to the diet was con...

Embodiment 2

[0230] Example 2: Effect of IMF Containing Increased sn2 Palmitate, Phospholipids and Large Lipid Globules on the Fatty Acid Composition of Red Blood Cell (RBC) Membranes

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Abstract

An early in life nutritional intervention with a lipid component having both large lipid globules with phospholipids and an increased amount of palmitic acid in the sn-2 position in triglycerides werefound to improve the fatty acid composition of cell membranes, in particular brain membranes.

Description

technical field [0001] The present invention relates to the field of infant nutrition, and to effects on brain development. Background technique [0002] Breastfeeding is the best method of feeding babies. However, there are situations where breastfeeding is not feasible or less desirable. In these cases infant formula is a good substitute. The composition of modern infant formula is adjusted so that it can meet the many specific nutritional needs of rapidly growing and developing infants. [0003] It appears that improvements can still be made in the composition of infant formula. Early nutrition given during a specific period of infancy has a programming effect when the brain grows and develops rapidly and thus has long-term consequences on brain function. Breastfed infants had better scores on vision and developmental tests and had improved neurodevelopment than formula-fed infants. In particular, long-chain polyunsaturated fatty acids (LC-PUFAs) such as docosahexaen...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A23D9/013A61K31/201A61K31/202A61K31/683A23L33/00A23L33/12A61P25/32A61P25/28A61P25/24A61P25/22A61P25/16A61P25/30
CPCA23D9/013A61K31/201A61K31/202A61K31/683A23L33/40A23L33/12A61K31/20A23L33/115A61P25/16A61P25/22A61P25/24A61P25/28A61P25/30A61P25/32A61K2300/00A23L33/105A23L33/21A23V2002/00A23V2200/322A23V2250/1868A23V2250/1872A23V2250/1876A23V2250/194A23V2250/284
Inventor A·L·施皮尔E·M·范德比克D·S·阿克顿N·巴特克S·舍恩
Owner NV NUTRICIA
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