Looking for breakthrough ideas for innovation challenges? Try Patsnap Eureka!

Method for detecting 4-methoxymethacinone

A methoxymethcathinone and sample technology, applied in the detection field of 4-methoxymethcathinone, can solve the problem of lack of new psychoactive substances

Inactive Publication Date: 2019-10-18
INST OF FORENSIC SCI OF MIN OF PUBLIC SECURITY
View PDF2 Cites 0 Cited by
  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

At present, the research on new psychoactive substances in my country is still very scarce, and the qualitative and quantitative detection method for the controlled 4-methoxymethcathinone is still blank. Therefore, it is urgent to establish a qualitative and quantitative detection method for the investigation and prosecution of related cases. Good technical support

Method used

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
View more

Image

Smart Image Click on the blue labels to locate them in the text.
Viewing Examples
Smart Image
  • Method for detecting 4-methoxymethacinone
  • Method for detecting 4-methoxymethacinone
  • Method for detecting 4-methoxymethacinone

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0099] Embodiment 1, carry out qualitative analysis to the Methedrone in the suspected drug sample with gas chromatography-mass spectrometry (GC-MS)

[0100] 1. Reagents and standard substances, instruments and measuring instruments

[0101] 1.1 Reagents and standard substances

[0102] All reagents used in this method are of analytical grade.

[0103] Extraction reagent: Methanol.

[0104] Traceable reference material: Methedrone.

[0105] 1.2 Instruments and measuring instruments

[0106] Gas Chromatograph (GC) equipped with Flame Ionization Detector (FID).

[0107] Gas chromatography-mass spectrometry (GC-MS), a quadrupole mass spectrometer equipped with a standard electron impact (EI) source.

[0108] centrifuge.

[0109] Electronic balance, actual division value d=0.01mg.

[0110] oscillator.

[0111] 10mL and 1mL pipettes or pipettes.

[0112] 10mL bottle top pipette.

[0113] Note: All instruments and measuring instruments involved must pass the metrological v...

Embodiment 2

[0138] Embodiment 2, gas chromatography-hydrogen flame ionization detector (GC-FID) carries out quantitative analysis to the Methedrone in the suspected drug sample

[0139] 1. Reagents and standard substances, instruments and measuring instruments

[0140] 1.1 Reagents and standard substances

[0141] All reagents used in this method are of analytical grade.

[0142] Extraction reagent: Methanol.

[0143] Traceable reference material: Methedrone.

[0144] 1.2 Instruments and measuring instruments

[0145] Gas Chromatograph (GC) equipped with Flame Ionization Detector (FID).

[0146] Gas chromatography-mass spectrometry (GC-MS), a quadrupole mass spectrometer equipped with a standard electron impact (EI) source.

[0147] centrifuge.

[0148] Electronic balance, actual division value d=0.01mg.

[0149] oscillator.

[0150] 10mL and 1mL pipettes or pipettes.

[0151] 10mL bottle top pipette.

[0152] Note: All instruments and measuring instruments involved must pass th...

Embodiment 3

[0231] Example 3, Qualitative analysis of Methedrone in suspected drug samples using liquid chromatography-tandem mass spectrometry (LC-MS / MS) in multiple reaction monitoring (MRM) mode

[0232] 1. Reagents and standard substances, instruments and measuring instruments

[0233] 1.1 Reagents and standard substances

[0234] The reagents used are chromatographically pure, and the test water is first-grade water (see GB / T 6682-2008). The reagents and standard substances include:

[0235] a) Reagents: methanol, acetonitrile, formic acid;

[0236] b) Traceable reference material: Methedrone;

[0237] c) 0.1% formic acid aqueous solution: measure 1mL of formic acid, add water to dissolve and dilute to 1000mL, mix well, filter through a 0.22μm filter membrane, and let it stand for use after ultrasonication;

[0238] d) Standard stock solution: Weigh Methedrone standard substance, dissolve it in methanol respectively, prepare a 2.5mg / mL standard stock solution, and store it in a re...

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
Login to View More

PUM

PropertyMeasurementUnit
collision energyaaaaaaaaaa
Login to View More

Abstract

The invention discloses a method for detecting 4-methoxymethacinone. One method disclosed by the invention comprises the following steps: performing an organic solvent extraction on Methedrone in a suspected drug sample; performing qualitative analysis by using gas chromatography-mass spectrometry (GC-MS); and performing quantitative analysis on Methedrone by using a gas chromatography-hydrogen flame ionization detector (GC-FID). The other method disclosed by the invention comprises the following steps: performing the organic solvent extraction on Methedrone in the suspected drug sample; performing qualitative analysis by using liquid chromatography-tandem mass spectrometry (LC-MS / MS) in a multiple reaction monitoring (MRM) mode; and performing quantitative analysis on Methedrone by usingthe liquid chromatography-diode array or ultraviolet detector (LC-DVD or LC-UV).

Description

technical field [0001] The invention belongs to the field of drug judicial detection, and in particular relates to a detection method of 4-methoxymethcathinone. Background technique [0002] New psychoactive substances, English name New psychoactive substances, referred to as NPS, early called Legal Highs or Designer Drug, Chinese called "legal stimulants" or "planning drugs", is the research and production of some controlled drugs in order to avoid crackdowns. The drug analogs obtained by structural modification have similar effects to controlled drugs, and some have stronger excitatory, hallucinogenic, and anesthetic effects. The United Nations Office on Drugs and Crime (UNODC) divides new psychoactive substances into 9 categories, namely: synthetic cannabinoids, cathinones, phenethylamines, tryptamines, piperazines, ketamines and benzene rings. Ridines, aminoindenes, plants and others. Among them, synthetic cannabinoids and cathinones are the most abused NPS. [0003] ...

Claims

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
Login to View More

Application Information

Patent Timeline
no application Login to View More
Patent Type & Authority Applications(China)
IPC IPC(8): G01N30/02G01N30/06G01N30/34
CPCG01N30/02G01N30/06G01N30/34G01N2030/047G01N2030/062G01N2030/342
Inventor 钱振华
Owner INST OF FORENSIC SCI OF MIN OF PUBLIC SECURITY
Who we serve
  • R&D Engineer
  • R&D Manager
  • IP Professional
Why Patsnap Eureka
  • Industry Leading Data Capabilities
  • Powerful AI technology
  • Patent DNA Extraction
Social media
Patsnap Eureka Blog
Learn More
PatSnap group products

Browse by: Latest US Patents, China's latest patents, Technical Efficacy Thesaurus, Application Domain, Technology Topic, Popular Technical Reports.

© 2024 PatSnap. All rights reserved.Legal|Privacy policy|Modern Slavery Act Transparency Statement|Sitemap|About US| Contact US: help@patsnap.com