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Preparation method of medical gauze for realizing rapid hemostasis

A gauze and fast technology, applied in the field of medical supplies, can solve the problems of hemostatic agents being easily oxidized and polluted by the external environment, aggravating the pain at the wound of the wounded, and reducing the hemostatic effect, so as to accelerate the coagulation speed, accelerate the hemostasis, and quickly hemostatic effect

Inactive Publication Date: 2019-11-05
朱清
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0003] Hemostatic gauze was invented by people to quickly stop bleeding in patients. Its efficacy does not depend on the normal coagulation matrix in the human body, and it is very effective in controlling bleeding in small blood vessels. Its endogenous hemostatic mechanism can achieve rapid hemostasis. The appearance of hemostatic gauze greatly It improves the hemostatic efficiency and provides guarantee for the subsequent treatment. However, the traditional hemostatic gauze needs to press the wound when it is used, which will not only increase the pain of the injured wound, but also have a general effect; The hemostatic agent is sprayed on the hemostatic gauze to make a composite hemostatic gauze, which accelerates blood coagulation through the exogenous coagulation pathway, thereby further improving the hemostatic efficiency. However, the hemostatic agent is easily affected by the external environment during long-term storage Oxidation and pollution, resulting in decreased hemostatic effect

Method used

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  • Preparation method of medical gauze for realizing rapid hemostasis

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0026] 1. a preparation method of medical gauze realizing quick hemostasis, is characterized in that, concrete preparation method is as follows:

[0027] 1) Pretreatment of degreasing gauze

[0028] Put the degreased gauze into the acetone solution according to the bath ratio of 1:10, soak it at room temperature for 2 hours, take it out and drain it, put it into the plasma reaction chamber, evacuate it to 2Pa, and then connect the oxygen until the internal oxygen flow is stable, and turn the radio frequency Set the power supply to 150W, process for 10s, then rinse with distilled water, dry in an oven at 80°C for 5 hours, take it out and put it in a microwave oven, microwave it for 2 hours at a microwave power of 100W and a turntable speed of 30r / min, and take it out at room temperature Stand by;

[0029] 2) Improved handling of conventional hemostatic agents

[0030] S1. Mix and stir 30 parts of absolute ethanol and 5 parts of distilled water evenly, then add 3 parts of buty...

Embodiment 2

[0042] 1. a preparation method of medical gauze realizing quick hemostasis, is characterized in that, concrete preparation method is as follows:

[0043] 1) Pretreatment of degreasing gauze

[0044] Put the degreased gauze into the acetone solution according to the bath ratio of 1:10, soak it at room temperature for 2.5 hours, take it out and drain it, put it into the plasma reaction chamber, evacuate it to 3Pa, and then connect oxygen until the internal oxygen flow is stable. The RF power was set at 180W, treated for 8s, rinsed with distilled water, dried in an oven at 90°C for 4h, taken out and placed in a microwave oven, microwaved for 1.5h at a microwave power of 150W and a turntable speed of 40r / min, taken out Stand at room temperature for later use;

[0045] 2) Improved handling of conventional hemostatic agents

[0046] S1. Mix and stir 35 parts of absolute ethanol and 7 parts of distilled water evenly, then add 4 parts of butylamine, continue stirring at 90r / min for ...

Embodiment 3

[0058] 1. a preparation method of medical gauze realizing quick hemostasis, is characterized in that, concrete preparation method is as follows:

[0059] 1) Pretreatment of degreasing gauze

[0060] Put the degreased gauze into the acetone solution according to the bath ratio of 1:10, soak it at room temperature for 3 hours, take it out and drain it, put it into the plasma reaction chamber, evacuate it to 5Pa, and then connect oxygen until the internal oxygen flow is stable. Set the power supply to 200W, process for 5 seconds, then rinse with distilled water, dry in an oven at 100°C for 3 hours, take it out and put it in a microwave oven, microwave it for 1 hour at a microwave power of 200W and a turntable speed of 50r / min, and take it out at room temperature Stand by;

[0061] 2) Improved handling of conventional hemostatic agents

[0062] S1. Mix and stir 40 parts of absolute ethanol and 10 parts of distilled water evenly, then add 5 parts of butylamine, continue stirring ...

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Abstract

The invention discloses a preparation method of medical gauze for realizing rapid hemostasis, wherein the preparation method comprises the following steps: 1) pretreatment of degreased gauze, 2) improvement treatment of a conventional hemostatic agent, and 3) immersion treatment of degreased gauze. Powder microspheres having an inner core loaded with a hemostatic material are formed by improvementtreatment of the conventional common hemostatic material, and then are attached on the treated degreased gauze to form the novel composite hemostatic gauze. The hemostatic gauze is stable in nature,safe and environmentally friendly, and has remarkable hemostatic effect. The hemostatic material attached to the gauze can be released according to the amount of blood in a wound, promotes blood coagulation, forms a certain squeezing effect on the wound in the use process, can accelerate the blood coagulation speed in the wound, and reduce the amount of blood loss, so as to achieve rapid hemostasis.

Description

technical field [0001] The invention belongs to the technical field of medical supplies, and in particular relates to a preparation method of medical gauze for rapid hemostasis. Background technique [0002] Blood is an important carrier for sending oxygen to the body. When the human body loses too much blood due to injury, the organs and cells will malfunction and fail, which will affect life safety. Uncontrolled bleeding has always been the main cause of casualties, and timely and effective hemostasis can save at least 30% of the casualties caused by excessive bleeding. Bleeding is also the main cause of traumatic death such as war wounds, falling injuries, and car accident injuries. Successful hemostasis within an effective time is of great significance to saving lives. All countries in the world attach great importance to the research on post-traumatic hemostasis measures. [0003] Hemostatic gauze was invented by people to quickly stop bleeding in patients. Its efficac...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61L15/44A61L15/18A61L15/42A61L15/28A61L15/20D06M13/127D06M10/08D06M10/00
CPCA61L15/18A61L15/20A61L15/28A61L15/42A61L15/425A61L15/44A61L2300/602A61L2400/04D06M10/003D06M10/08D06M13/127C08L3/02C08L5/04
Inventor 朱清
Owner 朱清
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