Viscosity detecting device for heparin sodium

Abstract

The present invention discloses a viscosity detecting device for heparin sodium, which comprises a glass box. A horizontal smooth plate is fixedly connected on an inner bottom wall of the glass box; aconnecting plate is fixedly connected with outer bottom walls at two ends of the glass box; one side of the connecting plate top end is fixedly connected with a scale; a middle part of the connectingplate top end is provided with a spring; and one end of the spring is fixedly connected with the connecting plate. Two sides of the glass box are provided with through holes; one end of a lifting rodis fixedly connected with a pointer; and the other end of the lifting rod is fixedly connected with a sticking plate. The inner walls at two ends of the glass box are rotatably connected with a rotating shaft; the surface of the rotating shaft is fixedly connected with a rotating rod; and a sliding slot is provided in the rotating rod. In the invention, when heparin sodium solution drops onto thehorizontal smooth plate, the rotating rod is toggled downward and rotates under the action of the rotating shaft, then a telescopic rod shrinks toward the inside of the sliding slot to drive the heparin sodium solution to be evenly spread on the horizontal smooth plate by a smearing plate; thereby, the uniform distribution effect is achieved.

Description

technical field [0001] The invention relates to the technical field of detection of pharmaceutical raw materials, in particular to a viscosity detection device for heparin sodium. Background technique [0002] Heparin sodium (Heparin sodium) can interfere with many aspects of the blood coagulation process, and has anticoagulant effects in vivo and in vitro. Inhibition of activated coagulation factors II, IX, X, XI, and XII, the consequences of which involve preventing platelet aggregation and destruction, hindering the formation of thromboplastin, preventing prothrombin from changing to thrombin, and inhibiting thrombin, thereby hindering the formation of fibroblasts The proteinogen becomes fibrin, thereby exerting an anticoagulant effect. [0003] When producing heparin sodium products in the biopharmaceutical industry, it is necessary to adjust the pH value according to the viscosity of the heparin sodium liquid. In the past, the liquid was extracted and then tested in th...

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Problems solved by technology

[0003] When producing heparin sodium products in the biopharmaceutical industry, it is necessary to adjust the pH value according to the viscosity of the heparin sodium liquid. In the past, the liquid was extracted and then tested in the laboratory, and then the pH value was adjusted according to the detected data. However, This cycle is long, which affects the whole process of producing heparin sodium. The detection accuracy of the existing detection device is not high, and the operation and use are relatively complicated.

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