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Spray for preventing and controlling oral helicobacter pylori, and preparation method of spray

A Helicobacter pylori and spray technology, which is applied in the prevention and control of oral Helicobacter pylori spray and its preparation, can solve the problems of easy resistance, large human body damage, and difficult swallowing of antibiotic pills, and achieve the removal of oral odor, The effect of maintaining oral health

Pending Publication Date: 2019-12-06
中合泰克(南京)生物科技有限公司
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0003] The existing common treatment method is antibiotic treatment. Long-term antibiotic treatment is more harmful to the human body and is prone to resistance. In addition, antibiotic pills are difficult for some people to swallow
Therefore, it is very important to use oral sprays instead of drugs, and the existing commonly used oral sprays generally have antibacterial and anti-inflammatory effects, but they are not effective in preventing and controlling oral Helicobacter pylori.

Method used

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  • Spray for preventing and controlling oral helicobacter pylori, and preparation method of spray
  • Spray for preventing and controlling oral helicobacter pylori, and preparation method of spray
  • Spray for preventing and controlling oral helicobacter pylori, and preparation method of spray

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0022] The sprays of 1 control group and 4 experimental groups were prepared according to the following ratio, and the sprays of the 4 experimental groups were experiment 1, experiment 2, experiment 3 and experiment 4 respectively.

[0023] Table 1 Spray Raw Material Ratio and Function

[0024]

[0025]

[0026] The production process of the spray is as follows:

[0027] 1. Content preparation:

[0028] (1) Mix the powder made from Rosa roxburghii (weigh the powder made from Rosa roxburghii according to the mass ratio) with Moringa leaf extract and lettuce extract (if there is no Rosa roxburghii in the formula, you only need to extract Moringa oleifera leaf mixed with lettuce extract), added into water, mixed evenly and heated to 70°C until dissolved, and after the solution was cooled to room temperature, ethanol, 70% sorbitol, glycerin, PEG-40 hydrogenated castor oil were added;

[0029] (2) Dissolving ovotransferrin and lysozyme at 50°C;

[0030] (3) Step (2) is add...

Embodiment 3

[0040] Performance Testing

[0041] Investigate the experimental method of preventing and controlling Helicobacter pylori and removing bad breath of this product: select 200 cases of Hp positive patients, the oral hygiene environment is similar, and the age deviation is small, and they are divided into treatment group 1 (40 cases), treatment group 2 (40 cases), Treatment group 3 (40 examples), treatment group 4 (40 examples) matched group (40 examples), treatment group 1, treatment group 2, treatment group 3 and treatment group 4 adopt experiment 1, experiment 2, experiment 2 in embodiment 2 respectively. The sprays obtained in Experiment 3 and Experiment 4 were sprayed into the mouth twice a day (once in the morning and evening), and the control group was sprayed in the mouth using the spray obtained in the control group in Example 2, 2 times a day (once in the morning and evening), and the use cycle was 1 month, 1 month after stopping the drug, the negative rate and the remo...

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Abstract

The invention discloses a spray for preventing and controlling oral helicobacter pylori, and a preparation method of the spray, and particularly relates to the technical field of oral sprays. The prepared spray is prepared from ovotransferrin, lysozyme, a moringa oleifera leaf extract and an asparagus lettuce extract. The spray can inhibit or eliminate the oral helicobacter pylori, the oral healthis maintained, and the oral peculiar smell is removed.

Description

technical field [0001] The invention belongs to the technical field of oral sprays, in particular to a spray for preventing and controlling oral Helicobacter pylori and a preparation method thereof. Background technique [0002] Oral Helicobacter pylori is a kind of bacteria in the oral cavity and stomach, which can cause stomach diseases. It often causes chronic gastrointestinal diseases and gastric ulcers. If measures are not taken in time, malignant lesions may occur and induce cancer. [0003] Existing common treatment method is to adopt antibiotic treatment, and long-term antibiotic treatment is bigger to human body damage and easily produces resistance, and in addition, antibiotic pill is difficult to swallow for some people. So it is very important to adopt oral spray instead of medicine, and the existing commonly used oral spray generally has antibacterial and anti-inflammatory effects, but it is not good for the prevention and control of oral Helicobacter pylori. ...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K38/47A61K9/12A61P31/04A61P1/02A61K38/40A61K36/28
CPCA61K38/47C12Y302/01017A61K38/40A61K36/185A61K36/28A61K9/006A61K47/44A61P31/04A61P1/02A61K9/12A61K2300/00
Inventor 张学记程晓紊吴耀辉
Owner 中合泰克(南京)生物科技有限公司
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