External fine pellet fat preparation all-in-one machine

Abstract

An external fine pellet fat preparation all-in-one machine comprises a fat collection tank 6 and a support 9, and further comprises a fat cutter, a negative pressure generator 94 and a negative pressure tank group 92 which are installed on the support, wherein the fat cutter is installed on the support 9 through a fixing frame 7, the negative pressure generator 94 is connected with the negative pressure tank group 92 through a pipeline, and the negative pressure tank group 92 is connected with a negative pressure connector 69 of the fat collection tank 6 through a pipeline. The external fine pellet fat preparation all-in-one machine solves the problems that in the fat transplantation process, fat suction wastes time and labor, content of ADSCs (adipose-derived stem cells) is low, fat is lack of extracellular matrix, pollution is easily caused in the purification process and the like.

Description

technical field [0001] The invention relates to an all-in-one machine for preparing fine-particle fat in vitro, in particular to an all-in-one machine for preparing fine-grain fat in vitro for fat transplantation. Background technique [0002] Autologous fat has been widely used in clinical practice due to its rich sources, convenient material collection, no rejection, simple operation, good filling shape, no disease infection, and no scar left after surgery. Common means of wound repair. But its transplant survival rate, especially the uncertainty of long-term survival is still the main obstacle limiting its application. Improving the survival rate of transplanted fat, especially the long-term survival rate, is still an urgent problem to be solved. A large number of studies have shown that currently only 50%-80% of the transplanted fat tissue volume can be retained. [0003] Studies have shown that in the early stage of transplantation, adipose tissue is in a state of is...

AI Technical Summary

Problems solved by technology

Although liposuction with a small-diameter liposuction tube has many advantages, the content of ADSCs in the aspirated fat particles is low. The reason may be related to the fact that ADSCs are mainly distributed around the interstitial blood vessels and fascial connective tissue of adipose tissue. The tissue of blood vessels and fascial connective tissue is relatively dense and tough, which leads to significantly lower ADSCs content and extracellular matrix in the fat obtained from the small-bore liposuction tube than those in the donor area.

[0006] The current application number is: 201910125174.3, the patent name is an all-in-one machine for in vitro fine particle fat preparation, which discloses a device that uses a large-diameter liposuction tube to suck fat, and then cuts fat through a cutting device. This device has high liposuction efficiency and is easy to transplant. The survival rate of post-fat is high, which can solve the above technical problems. However, further research on this device found that the cutting effect of the cutting part is unstable. The fat particles after cutting are large and small. Its collection part is inconvenient to disassemble, maintain and disinfect, and may cause lipobacteria contamination

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