Ointment for clearing heat, cooling blood, stopping bleeding, diminishing swelling and promoting wound healing and preparation method thereof

A technology for hemostasis, detumescence, and wound healing, applied in the field of medicine, can solve the problems of wound scarring, slow wound healing, pigmentation, etc., and achieve the effect of promoting tissue repair

Inactive Publication Date: 2020-02-14
XIAN CHIHO PHARMA
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

However, because it is an oral preparation, patients are reluctant to take oral drugs when traumatic bleeding occurs. Currently, topical hemostatic drugs generally have a small amount of wound adhesion, easy to fall off, slow hemostasis, slow wound healing, and scars and pigmentation on the wound after healing. Precipitation and other issues

Method used

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  • Ointment for clearing heat, cooling blood, stopping bleeding, diminishing swelling and promoting wound healing and preparation method thereof
  • Ointment for clearing heat, cooling blood, stopping bleeding, diminishing swelling and promoting wound healing and preparation method thereof
  • Ointment for clearing heat, cooling blood, stopping bleeding, diminishing swelling and promoting wound healing and preparation method thereof

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0026] Composition of raw materials: 50 parts of rhubarb, 40 parts of coptis, 40 parts of Panax notoginseng, 20 parts of Angelica dahurica, 40 parts of donkey-hide gelatin, 30 parts of calcined keel, 30 parts of baiji, 20 parts of vinegar myrrh, 30 parts of sea octopus, 40 parts of madder , 10 parts of dragon's blood, 2 parts of pearls, 2 parts of borneol, 5 parts of licorice.

[0027] Ointment prescription: every 100g includes the following components by weight: drug dry paste powder 5g, chitosan hydrochloride 1g, β-sodium glycerophosphate 8g, isopropyl myristate 15g, polyethylene glycol 40010g, spit Wen 8015g, polyoxyethylene castor oil 5g, ethyl p-hydroxybenzoate 0.1 part, water 41g.

[0028] Preparation process of drug dry paste powder: composed of dry paste powder, superfine powder, donkey-hide gelatin, and borneol, including the following steps:

[0029] (1) Mix rhubarb, coptis, notoginseng and Angelica dahurica, add 5 times the amount of 70 ethanol to infiltrate for 45 m...

Embodiment 2

[0037] Composition of raw materials: 80 parts of rhubarb, 60 parts of coptis, 60 parts of Panax notoginseng, 40 parts of Angelica dahurica, 60 parts of donkey-hide gelatin, 55 parts of calcined keel, 55 parts of baiji, 40 parts of vinegar myrrh, 55 parts of sea octopus, 60 parts of madder , 20 parts of dragon's blood, 10 parts of pearls, 10 parts of borneol, 20 parts of licorice.

[0038] Ointment prescription: every 100g includes the following components by weight: drug dry paste powder 15g, carboxymethyl chitosan 3g, β-sodium glycerophosphate 4g, isopropyl myristate 20g, glycerol 20g, Tween 8020g, 10g of polyoxyethylene castor oil, 0.5 part of ethyl p-hydroxybenzoate, and the balance is 11.5g of water.

[0039] Preparation process of drug dry paste powder: composed of dry paste powder, superfine powder, and borneol, including the following steps:

[0040] (1) Mix rhubarb, coptis, notoginseng and Angelica dahurica, add 10 times the amount of 85% ethanol to infiltrate for 60 ...

Embodiment 3

[0048] Composition of raw materials: 65 parts of rhubarb, 50 parts of coptis, 50 parts of Panax notoginseng, 31 parts of Angelica dahurica, 50 parts of donkey-hide gelatin, 44 parts of calcined keel, 44 parts of baiji, 31 parts of vinegar myrrh, 44 parts of sea octopus, 50 parts of madder , 12 parts of dragon's blood, 4 parts of pearls, 4 parts of borneol, 11 parts of licorice.

[0049] Ointment prescription: every 100g includes the following components by weight: 10g of dry drug paste powder, 1.5g of chitosan hydrochloride, 6g of sodium β-glycerophosphate, 18g of isopropyl myristate, 15g of glycerol, Wen 8018g, polyoxyethylene castor oil 7.5g, ethyl p-hydroxybenzoate 0.25 parts, water 24g.

[0050] Preparation process of drug dry paste powder: composed of dry paste powder, superfine powder, donkey-hide gelatin, and borneol, including the following steps:

[0051] (1) Mix rhubarb, coptis, notoginseng and Angelica dahurica, add 8 times the amount of 80% ethanol to infiltrate f...

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Abstract

The invention discloses ointment for clearing heat, cooling blood, stopping bleeding, diminishing swelling and promoting wound healing and a preparation method thereof. The ointment is prepared from the following raw materials: rheum officinale, rhizoma coptidis, radix notoginseng, radix angelicae dahuricae, colla corii asini, calcined dragon bones, rhizoma bletillae, myrrh, cuttlebone, radix rubiae, dragon's blood, pearl, borneol and liquorice roots. The ointment has very good curative effects on various skin trauma bleeding, ulcer, ulceration and the like, the treatment period is short, andthe pain and economic burden of a patient are greatly reduced. The ointment directly acts on an affected part, improves the absorption efficiency of medicines, promotes rapid healing of bleeding points and ulcer surfaces, has the advantages of rapid curative effect, short course of treatment, pure traditional Chinese medicine preparation, no toxic or side effect, wide and easily available medicinesource, convenient application, external application to the affected part, small dosage, no pain and no recurrence after healing.

Description

technical field [0001] The invention belongs to the technical field of medicine, and in particular relates to an ointment for clearing away heat and cooling blood, stopping bleeding and reducing swelling, and promoting wound healing and a preparation method thereof. Background technique [0002] Traumatic hemorrhage, metrorrhagia, hematemesis and blood in the stool are often frequently-occurring and difficult diseases in TCM blood syndrome. There is information displayed. Hematemesis and hematochezia incidence rate is more than 12%, mainly occurs in young and middle-aged men, and men are more than women. Zhikang Capsule is the exclusive product of Qianhe Pharmaceutical Co., Ltd., and has been clinically effective since it was launched. The prescription composition: rhubarb, coptis, angelica, licorice, madder, donkey-hide gelatin, panax notoginseng, baiji, pearl, calcined keel, vinegar myrrh, seaweed Octopus, dragon's blood jerky, borneol, 14 flavors in total; functions and...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/898A61K9/06A61K47/10A61K47/14A61K47/44A61K47/26A61K47/36A61P7/04A61P17/02A61K31/045A61K35/02A61K35/36A61K35/618
CPCA61K36/708A61K36/718A61K36/258A61K36/232A61K35/36A61K35/02A61K36/898A61K36/328A61K35/618A61K36/74A61K36/896A61K31/045A61K36/484A61K9/06A61K9/0014A61K47/10A61K47/14A61K47/44A61K47/26A61K47/36A61P17/02A61P7/04A61K2236/333A61K2236/331A61K2236/51A61K2236/39
Inventor 胡小虎张琼李小波谭祥和吕慧锋
Owner XIAN CHIHO PHARMA
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