Application of pulsatilla saponin B4 in preparing medicine for treating/preventing viral pneumonia

A technology of Pulsatilla saponin and viral pneumonia, applied in the field of medicine, can solve problems such as no reports on the effect, and achieve the effect of remarkable effect.

Pending Publication Date: 2020-06-05
广西馨海药业科技有限公司
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

At present, there is no report on the effect of Pulsatilla saponin B4 on the prevention and treatment of viral pneumonia

Method used

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  • Application of pulsatilla saponin B4 in preparing medicine for treating/preventing viral pneumonia
  • Application of pulsatilla saponin B4 in preparing medicine for treating/preventing viral pneumonia
  • Application of pulsatilla saponin B4 in preparing medicine for treating/preventing viral pneumonia

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Embodiment Construction

[0019] The present invention will be further described in detail below in conjunction with the accompanying drawings, so that those skilled in the art can implement it with reference to the description.

[0020] It should be understood that terms such as "having", "comprising" and "including" as used herein do not entail the presence or addition of one or more other elements or combinations thereof.

[0021] It should be noted that the experimental methods described in the following embodiments, unless otherwise specified, are conventional methods, and the reagents and materials, unless otherwise specified, can be obtained from commercial sources.

[0022] 1. Materials

[0023] 1.1 Experimental animals

[0024] Healthy BALB / c mice, 60 males and 60 males, SPF grade, weighing 18-20 g, were provided by Beijing Weitong Lihua Experimental Animal Technology Co., Ltd., animal qualification certificate number: SCXK Beijing 2016-0006.

[0025] 1.2 Drugs and reagents

[0026] Pulsati...

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PUM

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Abstract

The invention discloses application of pulsatilla saponin B4 in preparing a medicine for treating/preventing influenza virus-induced viral pneumonia of mammals including human beings. The pulsatilla saponin B4 has a protection function on FM1 induced viral pneumonia, and the protection mechanism may be related to reduction of expression of inflammatory factors and inhibiting expression of proteinsTLR4, MD2 and MyD88.

Description

technical field [0001] The invention relates to the technical field of medicine. More specifically, the present invention relates to the use of Pulsatilla saponin B4 in the preparation of drugs for the treatment / prevention of viral pneumonia. Background technique [0002] Influenza A (H1N1) first broke out in Mexico in April 2009, and then spread globally. China classifies Influenza A virus H1N1 as a Class B infectious disease and adopts preventive and control measures for Class A infectious diseases. Influenza viruses are highly variable and contagious, and immunocompromised people are vulnerable. When the influenza virus proliferates in the lung bronchial epithelial cells and lung tissue, it can cause severe pathological tissue damage, such as pulmonary edema, inflammatory exudation, congestion, etc., leading to bronchitis and interstitial pneumonia. Severe infection, Respiratory failure, multiple organ dysfunction, etc., even lead to death, seriously affecting the qual...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K31/704A61P11/00A61P31/16
CPCA61K31/704A61P11/00A61P31/16
Inventor 杨世林
Owner 广西馨海药业科技有限公司
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