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Vessel Segmentation Method of Fundus Image Based on Multi-scale Features of Fully Convolutional Neural Network

A convolutional neural network and multi-scale feature technology, applied in neural learning methods, biological neural network models, image analysis, etc., can solve the problem that neural networks cannot segment blood vessel images well, have multiple additional conditions, and require high image quality, etc. problem, to achieve the effect of avoiding the image processing process

Active Publication Date: 2021-06-18
ZHEJIANG UNIV OF TECH
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AI Technical Summary

Problems solved by technology

Unsupervised segmentation methods do not require prior label information, but have high requirements for image quality, usually require more additional conditions, and the segmentation effect is slightly worse
The supervised method is mainly based on the extracted feature classifier to achieve the purpose of identifying blood vessels and background. The neural network model needs to extract image features layer by layer, and it is easy to lose a lot of useful information, resulting in the neural network not being able to segment blood vessel images well.

Method used

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  • Vessel Segmentation Method of Fundus Image Based on Multi-scale Features of Fully Convolutional Neural Network
  • Vessel Segmentation Method of Fundus Image Based on Multi-scale Features of Fully Convolutional Neural Network

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Embodiment Construction

[0014] The present invention will be further described below in combination with schematic diagrams.

[0015] refer to figure 1 and figure 2 , a blood vessel segmentation method for fundus images based on multi-scale features of fully convolutional neural networks, including the following steps:

[0016] 1) Image preprocessing

[0017] The quality of the image directly affects the accuracy of the effect. The purpose of image preprocessing is mainly to eliminate irrelevant information in the image, simplify the data to the greatest extent, and overcome image interference. First, assign different weights to the R, G, and B channel values ​​of each color retinal image according to the formula Gray=R*0.299+G*0.587+B*0.114, and convert the image into a single-channel grayscale image. Normalization is then performed to improve the contrast and clarity of blood vessels in the picture. Finally, Gamma correction is performed to enhance the contrast of the image. After preprocessi...

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Abstract

A blood vessel segmentation method for fundus images based on multi-scale features of fully convolutional neural networks, comprising the following steps: 1) Preprocessing the retinal images of the fundus; 2) Segmenting the preprocessed images into image blocks for data expansion; 3) Construct a convolutional neural network model, and use the expanded data for network training; 4) Test the trained model to obtain segmentation results. In the present invention, by connecting one encoding and two different decoding structures, and adopting multiple skip connections, it can overcome the shortcomings of the small number of blood vessel image data sets and the low segmentation accuracy caused by low image quality, and more fully integrate images of different depths. Features, and effectively alleviate the gradient disappearance problem caused by the increase of network depth, compared with traditional segmentation methods, it has higher accuracy and higher robustness.

Description

technical field [0001] The invention relates to the fields of medical image processing and computer vision, in particular to a method for segmenting blood vessels in fundus images based on convolutional neural networks. Background technique [0002] The fundus retinal microvascular network is the same as the face, fingerprints, palm prints and other human characteristics, and also has individual uniqueness. The distribution, direction, thickness, curvature and other characteristics of the retinal blood vessels are different for each person, so the fundus information can be used for biometric identification. Furthermore, of all the deeper microvascular circulatory networks in the human body, the only one that can be directly visualized noninvasively is that of the retinal microvasculature. Normally, the vascular network remains unchanged for a long time, but cardiovascular and cerebrovascular diseases such as diabetes and hypertension can lead to changes in the structure and ...

Claims

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Application Information

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Patent Type & Authority Patents(China)
IPC IPC(8): G06T7/11G06T7/00G06N3/04G06N3/08
CPCG06T7/10G06T7/0012G06N3/08G06T2207/30041G06T2207/30101G06N3/045
Inventor 刘义鹏芮雪蒋莉王海霞陈朋梁荣华
Owner ZHEJIANG UNIV OF TECH
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