The application discloses a kind of nnUNet zebra fish
juvenile whole brain vascular
system segmentation methods based on autonomous
data set training, it is related to high-resolution
imaging technology,
image processing and medical
image segmentation field, the method makes full use of zebra fish live transparency and fluorescent
label advantage, obtains high-resolution whole brain three-dimensional vascular image data, and constructs high-quality segmentation
truth value database by semi-
automatic segmentation and artificial correction, training is carried out using nnU-Net
deep learning model, realize the three-dimensional
automatic segmentation of zebra fish brain vascular
system signal.The application method significantly improves the degree of
automation and precision of
image segmentation, effectively solves the problems of low efficiency, high artificial dependence and poor
repeatability of traditional brain
vascular segmentation.The method is suitable for large-scale high-
throughput data processing, can provide efficient, standardized
image processing scheme for zebra fish brain vascular development mechanism and brain
vascular disease model research, and has wide application prospect.